Plasmodium falciparum var genes are regulated by two regions with separate promoters, one upstream of the coding region and a second within the intron.
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Antigenic variation in Plasmodium falciparum is associated with movement of var loci between subnuclear locationsSub-grouping of Plasmodium falciparum 3D7 var genes based on sequence analysis of coding and non-coding regionsTranscriptome analysis of antigenic variation in Plasmodium falciparum--var silencing is not dependent on antisense RNAMutually exclusive expression of virulence genes by malaria parasites is regulated independently of antigen production.Expression of P. falciparum var genes involves exchange of the histone variant H2A.Z at the promoterSurface co-expression of two different PfEMP1 antigens on single plasmodium falciparum-infected erythrocytes facilitates binding to ICAM1 and PECAM1Plasmodium falciparum heterochromatin protein 1 marks genomic loci linked to phenotypic variation of exported virulence factorsRecruitment of PfSET2 by RNA polymerase II to variant antigen encoding loci contributes to antigenic variation in P. falciparumEnlightening the malaria parasite life cycle: bioluminescent Plasmodium in fundamental and applied researchUse of peptide nucleic acids to manipulate gene expression in the malaria parasite Plasmodium falciparumA transcriptional switch underlies commitment to sexual development in malaria parasitesH3.3 demarcates GC-rich coding and subtelomeric regions and serves as potential memory mark for virulence gene expression in Plasmodium falciparumA novel Plasmodium falciparum SR protein is an alternative splicing factor required for the parasites' proliferation in human erythrocytesDefault Pathway of var2csa switching and translational repression in Plasmodium falciparumDifferential, positional-dependent transcriptional response of antigenic variation (var) genes to biological stress in Plasmodium falciparum.Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assayNucleosome landscape and control of transcription in the human malaria parasiteA var gene upstream element controls protein synthesis at the level of translation initiation in Plasmodium falciparumAntigenic variation in Plasmodium falciparum malaria involves a highly structured switching patternA silenced Plasmodium falciparum var promoter can be activated in vivo through spontaneous deletion of a silencing element in the intron.CRISPR/Cas9 Genome Editing Reveals That the Intron Is Not Essential for var2csa Gene Activation or Silencing in Plasmodium falciparumFrom in vivo to in vitro: dynamic analysis of Plasmodium falciparum var gene expression patterns of patient isolates during adaptation to culture.Profile of Thomas E. WellemsDirectional gene expression and antisense transcripts in sexual and asexual stages of Plasmodium falciparum.Noncoding RNAs as emerging regulators of Plasmodium falciparum virulence gene expression.In Silico Prediction of Evolutionarily Conserved GC-Rich Elements Associated with Antigenic Proteins of Plasmodium falciparum.Erasing the epigenetic memory and beginning to switch--the onset of antigenic switching of var genes in Plasmodium falciparumCloning and molecular analysis of the aspartic protease Sc-ASP110 gene transcript in Steinernema carpocapsae.Spleen-dependent regulation of antigenic variation in malaria parasites: Plasmodium knowlesi SICAvar expression profiles in splenic and asplenic hosts.Plasmodium falciparum var gene silencing is determined by cis DNA elements that form stable and heritable interactions.Antisense long noncoding RNAs regulate var gene activation in the malaria parasite Plasmodium falciparum.Epigenetic memory at malaria virulence genes.Overcoming antigenic diversity and improving vaccines using DNA shuffling and screening technologies.A novel downstream regulatory element cooperates with the silencing machinery to repress EPA1 expression in Candida glabrata.Molecular aspects of Plasmodium falciparum Infection during pregnancy.PfGCN5-mediated histone H3 acetylation plays a key role in gene expression in Plasmodium falciparum.Mechanisms underlying mutually exclusive expression of virulence genes by malaria parasites.Punctuated chromatin states regulate Plasmodium falciparum antigenic variation at the intron and 2 kb upstream regionsIn Vitro Variant Surface Antigen Expression in Plasmodium falciparum Parasites from a Semi-Immune Individual Is Not Correlated with Var Gene Transcription.Alterations in local chromatin environment are involved in silencing and activation of subtelomeric var genes in Plasmodium falciparum.
P2860
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P2860
Plasmodium falciparum var genes are regulated by two regions with separate promoters, one upstream of the coding region and a second within the intron.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
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name
Plasmodium falciparum var gene ...... nd a second within the intron.
@en
Plasmodium falciparum var gene ...... nd a second within the intron.
@nl
type
label
Plasmodium falciparum var gene ...... nd a second within the intron.
@en
Plasmodium falciparum var gene ...... nd a second within the intron.
@nl
prefLabel
Plasmodium falciparum var gene ...... nd a second within the intron.
@en
Plasmodium falciparum var gene ...... nd a second within the intron.
@nl
P2093
P2860
P356
P1476
Plasmodium falciparum var gene ...... nd a second within the intron.
@en
P2093
Kirk W Deitsch
Laila Gannoun-Zaki
Michael S Calderwood
Thomas E Wellems
P2860
P304
34125-34132
P356
10.1074/JBC.M213065200
P407
P577
2003-06-27T00:00:00Z