A nonclinical safety assessment of MnTE-2-PyP, a manganese porphyrin.

A nonclinical safety assessment of MnTE-2-PyP, a manganese porphyrin.

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http://www.wikidata.org/entity/Q48552406
SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathwaysAn educational overview of the chemistry, biochemistry and therapeutic aspects of Mn porphyrins--From superoxide dismutation to H2O2-driven pathways.Mn porphyrin in combination with ascorbate acts as a pro-oxidant and mediates caspase-independent cancer cell death.Manganoporphyrins and ascorbate enhance gemcitabine cytotoxicity in pancreatic cancer.Robust rat pulmonary radioprotection by a lipophilic Mn N-alkylpyridylporphyrin, MnTnHex-2-PyP(5+).Therapeutic potential of peroxynitrite decomposition catalysts: a patent review.Catalytic antioxidant therapy by metallodrugs: lessons from metallocorroles.MnTE-2-PyP Treatment, or NOX4 Inhibition, Protects against Radiation-Induced Damage in Mouse Primary Prostate Fibroblasts by Inhibiting the TGF-Beta 1 Signaling Pathway.Nonclinical Safety and Toxicokinetics of MnTnBuOE-2-PyP5+ (BMX-001).Treatment with a Catalytic Superoxide Dismutase (SOD) Mimetic Improves Liver Steatosis, Insulin Sensitivity, and Inflammation in Obesity-Induced Type 2 Diabetes.The SOD Mimic, MnTE-2-PyP, Protects from Chronic Fibrosis and Inflammation in Irradiated Normal Pelvic Tissues.Radiation-mediated tumor growth inhibition is significantly enhanced with redox-active compounds that cycle with ascorbate.Challenges encountered during development of Mn porphyrin-based, potent redox-active drug and superoxide dismutase mimic, MnTnBuOE-2-PyP5+, and its alkoxyalkyl analogues.
P2860

A nonclinical safety assessment of MnTE-2-PyP, a manganese porphyrin.

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http://www.wikidata.org/entity/Q48552406
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2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
A nonclinical safety assessment of MnTE-2-PyP, a manganese porphyrin.
@en
A nonclinical safety assessment of MnTE-2-PyP, a manganese porphyrin.
@nl
type
label
A nonclinical safety assessment of MnTE-2-PyP, a manganese porphyrin.
@en
A nonclinical safety assessment of MnTE-2-PyP, a manganese porphyrin.
@nl
prefLabel
A nonclinical safety assessment of MnTE-2-PyP, a manganese porphyrin.
@en
A nonclinical safety assessment of MnTE-2-PyP, a manganese porphyrin.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P356
P1433
P1476
A nonclinical safety assessment of MnTE-2-PyP, a manganese porphyrin.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698