about
Computational Prediction of RNA-Binding Proteins and Binding SitesCyclometalated Iridium(III) Complexes as AIE Phosphorescent Probes for Real-Time Monitoring of Mitophagy in Living Cells.Non-ATP-Mimetic Organometallic Protein Kinase InhibitorIdentification of an in vivo orally active dual-binding protein-protein interaction inhibitor targeting TNFα through combined in silico/in vitro/in vivo screeningCheminformatics-aided discovery of small-molecule Protein-Protein Interaction (PPI) dual inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL).Cytotoxicity of Pyrazine-Based Cyclometalated (C^Npz^C)Au(III) Carbene Complexes: Impact of the Nature of the Ancillary Ligand on the Biological Properties.Metal complexes as potential modulators of inflammatory and autoimmune responses.Cytotoxic effects of the compound cis-tetraammine(oxalato)ruthenium(III) dithionate on K-562 human chronic myelogenous leukemia cells.Cyclometalated Iridium(III) Complexes as Two-Photon Phosphorescent Probes for Specific Mitochondrial Dynamics Tracking in Living Cells.SerpentinaDB: a database of plant-derived molecules of Rauvolfia serpentina.Inhibition of the p53/hDM2 protein-protein interaction by cyclometallated iridium(III) compounds.Identification of an iridium(III) complex with anti-bacterial and anti-cancer activity.Ruthenium(II) Complexes with 2-Phenylimidazo[4,5-f][1,10]phenanthroline Derivatives that Strongly Combat Cisplatin-Resistant Tumor CellsEster-Modified Cyclometalated Iridium(III) Complexes as Mitochondria-Targeting Anticancer Agents.Organoiridium complexes: anticancer agents and catalystsTargeting unimolecular G-quadruplex nucleic acids: a new paradigm for the drug discovery?Growth rate analysis and efficient experimental design for tumor xenograft studies.Rhodium complexes as therapeutic agents.Fullerenes and their derivatives as inhibitors of tumor necrosis factor-α with highly promoted affinities.A metal-based tumour necrosis factor-alpha converting enzyme inhibitor.Dinuclear [{(p-cym)RuCl}2(μ-phpy)](PF6)2 and heterodinuclear [(ppy)2Ir(μ-phpy)Ru(p-cym)Cl](PF6)2 complexes: synthesis, structure and anticancer activity.Aqueous chemistry and antiproliferative activity of a pyrone-based phosphoramidate Ru(arene) anticancer agent.2'-Epi-uscharin from the latex of Calotropis gigantea with HIF-1 inhibitory activity.Cyclometalated iridium(III)-β-carboline complexes as potent autophagy-inducing agents.An iridium(iii)-based irreversible protein-protein interaction inhibitor of BRD4 as a potent anticancer agent.Furanodiene Induces Extrinsic and Intrinsic Apoptosis in Doxorubicin-Resistant MCF-7 Breast Cancer Cells via NF-κB-Independent Mechanism.Iridium(III) Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II.Mixed-ligand iridium(iii) complexes as photodynamic anticancer agents.Valproic Acid-Functionalized Cyclometalated Iridium(III) Complexes as Mitochondria-Targeting Anticancer Agents.Enantiopure Cycloiridiated Complexes Bearing a Pentahelicenic N-Heterocyclic Carbene and Displaying Long-Lived Circularly Polarized Phosphorescence.Rational design of NIR-emitting iridium(iii) complexes for multimodal phosphorescence imaging of mitochondria under two-photon excitation.Suzuki Cross-Coupling for Post-Complexation Derivatization of Non-Racemic Bis-Cyclometalated Iridium(III) Complexes.Gold-Catalyzed Cycloisomerization and Diels-Alder Reaction of 1,4,9-Dienyne Esters to 3 a,6-Methanoisoindole Esters with Pro-Inflammatory Cytokine Antagonist Activity.Synthesis, characterization, in silico ADMET prediction, and protein binding analysis of a novel zinc(II) Schiff-base complex: Application of multi-spectroscopic and computational techniques.Coumarin-appended phosphorescent cyclometalated iridium(iii) complexes as mitochondria-targeted theranostic anticancer agents.Cyclometallated iridium complexes inducing paraptotic cell death like natural products: synthesis, structure and mechanistic aspects.Metal complexes as "protein surface mimetics".DNA Interaction, Photocleavage and Topoisomerase I Inhibition by Ru(II) Complex with a New Ligand Possessing Phenazine Unit.Labile ruthenium(ii) complexes with extended phenyl-substituted terpyridyl ligands: synthesis, aquation and anticancer evaluation.Design, Synthesis, and Evaluation of Dihydrobenzo[cd]indole-6-sulfonamide as TNF-α Inhibitors.
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh-hant
name
A metal-based inhibitor of tumor necrosis factor-α.
@en
A metal-based inhibitor of tumor necrosis factor-α.
@nl
type
label
A metal-based inhibitor of tumor necrosis factor-α.
@en
A metal-based inhibitor of tumor necrosis factor-α.
@nl
prefLabel
A metal-based inhibitor of tumor necrosis factor-α.
@en
A metal-based inhibitor of tumor necrosis factor-α.
@nl
P2093
P2860
P50
P356
P1476
A metal-based inhibitor of tumor necrosis factor-α.
@en
P2093
Chun-Yuen Wong
Daniel Shiu-Hin Chan
Hai-Jing Zhong
Ruben Abagyan
Zhen Cheng
P2860
P304
P356
10.1002/ANIE.201202937
P407
P577
2012-07-13T00:00:00Z