Involvement of Reactive Metabolites of Diclofenac in Cytotoxicity in Sandwich-Cultured Rat Hepatocytes.

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Abundance of Cytochromes in Hepatic Extracellular Vesicles Is Altered by Drugs Related With Drug-Induced Liver Injury

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Involvement of Reactive Metabolites of Diclofenac in Cytotoxicity in Sandwich-Cultured Rat Hepatocytes.

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2017 nî lūn-bûn

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2017年学术文章

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Involvement of Reactive Metabo ...... wich-Cultured Rat Hepatocytes.

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Involvement of Reactive Metabo ...... wich-Cultured Rat Hepatocytes.

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Involvement of Reactive Metabo ...... wich-Cultured Rat Hepatocytes.

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Involvement of Reactive Metabo ...... wich-Cultured Rat Hepatocytes.

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Involvement of Reactive Metabo ...... wich-Cultured Rat Hepatocytes.

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Involvement of Reactive Metabo ...... wich-Cultured Rat Hepatocytes.

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Involvement of Reactive Metabo ...... wich-Cultured Rat Hepatocytes.

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Atsushi Kawase

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Hiroaki Shimada

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Mai Shibata

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Masahiro Iwaki

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Ryota Hashimoto

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P2860

Human α/β hydrolase domain containing 10 (ABHD10) is responsible enzyme for deglucuronidation of mycophenolic acid acyl-glucuronide in liver

Diclofenac hepatitis

Preparation of isolated rat liver cells

Extrapolation of diclofenac clearance from in vitro microsomal metabolism data: role of acyl glucuronidation and sequential oxidative metabolism of the acyl glucuronide.

Dipeptidyl peptidase IV is a target for covalent adduct formation with the acyl glucuronide metabolite of the anti-inflammatory drug zomepirac.

The natural history of histologically proved drug induced liver disease.

The safety of newly approved medicines: do recent market removals mean there is a problem?

New concepts in immunology relevant to idiosyncratic drug reactions: the "danger hypothesis" and innate immune system.

Drug-induced hepatotoxicity.

Drug-induced liver disorders: implications for drug development and regulation.

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260-267

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scholarly article

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10.1177/1091581817700584

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2017-03-24T00:00:00Z

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28553770

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diclofenac

Involvement of Reactive Metabolites of Diclofenac in Cytotoxicity in Sandwich-Cultured Rat Hepatocytes.

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P2860

P2860

Involvement of Reactive Metabolites of Diclofenac in Cytotoxicity in Sandwich-Cultured Rat Hepatocytes.

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