Abnormal myotonic dystrophy protein kinase levels produce only mild myopathy in mice. - Wikidata - awgldk - TriplyDB

Abnormal myotonic dystrophy protein kinase levels produce only mild myopathy in mice.

Abnormal myotonic dystrophy protein kinase levels produce only mild myopathy in mice.

http://www.wikidata.org/entity/Q52200997

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Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy Myotonic dystrophy protein kinase phosphorylates the myosin phosphatase targeting subunit and inhibits myosin phosphatase activity Divergent mitochondrial and endoplasmic reticulum association of DMPK splice isoforms depends on unique sequence arrangements in tail anchors.MKBP, a novel member of the small heat shock protein family, binds and activates the myotonic dystrophy protein kinase Identification of a (CUG)n triplet repeat RNA-binding protein and its expression in myotonic dystrophy Myotonic dystrophy protein kinase is critical for nuclear envelope integrity Molecular basis for impaired muscle differentiation in myotonic dystrophy In vivo co-localisation of MBNL protein with DMPK expanded-repeat transcripts Altered phosphorylation and intracellular distribution of a (CUG)n triplet repeat RNA-binding protein in patients with myotonic dystrophy and in myotonin protein kinase knockout mice Incredible RNA: Dual Functions of Coding and Noncoding Muscle wasting in myotonic dystrophies: a model of premature aging Structure of dystrophia myotonica protein kinase RNA CUG repeats sequester CUGBP1 and alter protein levels and activity of CUGBP1 HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 ((3D)HSP27)Mice deficient in Six5 develop cataracts: implications for myotonic dystrophy Myofibrillar myopathy caused by a mutation in the motor domain of mouse MyHC IIb Heterozygous loss of Six5 in mice is sufficient to cause ocular cataracts Myotonic dystrophy protein kinase is involved in the modulation of the Ca2+ homeostasis in skeletal muscle cells Homodimerization through coiled-coil regions enhances activity of the myotonic dystrophy protein kinase Age of onset of RNA toxicity influences phenotypic severity: evidence from an inducible mouse model of myotonic dystrophy (DM1).Reversible model of RNA toxicity and cardiac conduction defects in myotonic dystrophy.Myotonic dystrophy protein kinase expressed in rat cardiac muscle is associated with sarcoplasmic reticulum and gap junctions.Role of myotonic dystrophy protein kinase (DMPK) in glucose homeostasis and muscle insulin action.Long tract of untranslated CAG repeats is deleterious in transgenic mice DMPK dosage alterations result in atrioventricular conduction abnormalities in a mouse myotonic dystrophy model.Rac-1 and Raf-1 kinases, components of distinct signaling pathways, activate myotonic dystrophy protein kinase.Triplet repeat expansion in neuromuscular disease.Myotonic dystrophy: the role of RNA CUG triplet repeats.Alternative splicing controls myotonic dystrophy protein kinase structure, enzymatic activity, and subcellular localization.RNA-protein interactions in unstable microsatellite diseases.Does (CUG)n repeat in DMPK mRNA 'paint' chromosome 19 to suppress distant genes to create the diverse phenotype of myotonic dystrophy?: A new hypothesis of long-range cis autosomal inactivation.RNase H-mediated degradation of toxic RNA in myotonic dystrophy type 1 Expanded CUG repeat RNAs form hairpins that activate the double-stranded RNA-dependent protein kinase PKR Localization of myotonic dystrophy protein kinase in human and rabbit tissues using a new panel of monoclonal antibodies.Myotonic dystrophy: molecular windows on a complex etiology.Long CTG tracts from the myotonic dystrophy gene induce deletions and rearrangements during recombination at the APRT locus in CHO cells.Hypothesis: neoplasms in myotonic dystrophy.Genome wide identification of aberrant alternative splicing events in myotonic dystrophy type 2.Lens epithelial changes and mutated gene expression in patients with myotonic dystrophy.Myotonic dystrophy: RNA pathogenesis comes into focus.

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P2860

Abnormal myotonic dystrophy protein kinase levels produce only mild myopathy in mice.

http://www.wikidata.org/entity/Q52200997

description

1996 nî lūn-bûn

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1996年の論文

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1996年学术文章

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1996年学术文章

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1996年学术文章

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1996年学术文章

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1996年学术文章

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1996年学术文章

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1996年學術文章

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1996年學術文章

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name

Abnormal myotonic dystrophy protein kinase levels produce only mild myopathy in mice.

@en

Abnormal myotonic dystrophy protein kinase levels produce only mild myopathy in mice.

@nl

type

label

Abnormal myotonic dystrophy protein kinase levels produce only mild myopathy in mice.

@en

Abnormal myotonic dystrophy protein kinase levels produce only mild myopathy in mice.

@nl

prefLabel

Abnormal myotonic dystrophy protein kinase levels produce only mild myopathy in mice.

@en

Abnormal myotonic dystrophy protein kinase levels produce only mild myopathy in mice.

@nl

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Nature Genetics

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Abnormal myotonic dystrophy protein kinase levels produce only mild myopathy in mice.

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P2093

Berns A

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Bächner D

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Coerwinkel M

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Dekker M

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Gohlsch B

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Groenen PJ

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Hameister H

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Jap PH

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Molenaar PC

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Nederhoff MG

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P2860

Cloning of the essential myotonic dystrophy region and mapping of the putative defect.

Molecular basis of myotonic dystrophy: expansion of a trinucleotide (CTG) repeat at the 3' end of a transcript encoding a protein kinase family member.

Characterization of the myotonic dystrophy region predicts multiple protein isoform-encoding mRNAs.

Foci of trinucleotide repeat transcripts in nuclei of myotonic dystrophy cells and tissues.

Neuroglycan C, a novel membrane-spanning chondroitin sulfate proteoglycan that is restricted to the brain.

Whole-mount in situ hybridization in the mouse embryo: gene expression in three dimensions.

Decreased myotonin-protein kinase in the skeletal and cardiac muscles in myotonic dystrophy.

Identification of a protein product of the myotonic dystrophy gene using peptide specific antibodies.

Somatic mosaicism, germline expansions, germline reversions and intergenerational reductions in myotonic dystrophy males: small pool PCR analyses

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316-324

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10.1038/NG0796-316

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