Cucurbitacin E-induced disruption of the actin and vimentin cytoskeleton in prostate carcinoma cells.
about
Cucurbitacins - a promising target for cancer therapyCucurbitacin I inhibits cell motility by indirectly interfering with actin dynamicsCucurbitacins - An insight into medicinal leads from natureIn vitro and in vivo antitumor activity of a novel semisynthetic derivative of cucurbitacin BInducement of apoptosis by cucurbitacin E, a tetracyclic triterpenes, through death receptor 5 in human cervical cancer cell lines.Cucurbitacin E induces apoptosis of human prostate cancer cells via cofilin-1 and mTORC1Actin-aggregating cucurbitacins from Physocarpus capitatus.Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2-STAT3 signaling pathway.The effectiveness of cucurbitacin B in BRCA1 defective breast cancer cells.Cucurbitacin E has neuroprotective properties and autophagic modulating activities on dopaminergic neuronsCucurbitacin B induced ATM-mediated DNA damage causes G2/M cell cycle arrest in a ROS-dependent manner.VASP activation via the Gα13/RhoA/PKA pathway mediates cucurbitacin-B-induced actin aggregation and cofilin-actin rod formationTargeting karyotypic complexity and chromosomal instability of cancer cells.Growth inhibitory effect of Cucurbitacin E on breast cancer cells.Cucurbitacin E inhibits osteosarcoma cells proliferation and invasion through attenuation of PI3K/AKT/mTOR signaling.Cucurbitacin D exhibits potent anti-cancer activity in cervical cancer.STAT3 inhibitor, cucurbitacin I, is a novel therapeutic agent for osteosarcoma.Therapeutic ROS targeting of GADD45γ in the induction of G2/M arrest in primary human colorectal cancer cell lines by cucurbitacin E.The Multifaceted Roles of STAT3 Signaling in the Progression of Prostate Cancer.Formation of cofilin-actin rods following cucurbitacin-B-induced actin aggregation depends on Slingshot homolog 1-mediated cofilin hyperactivation.Cucurbitacin E exhibits anti-inflammatory effect in RAW 264.7 cells via suppression of NF-κB nuclear translocation.Cucurbitacin E inhibits breast tumor metastasis by suppressing cell migration and invasion.Anti-proliferative effect of 23,24-dihydrocucurbitacin F on human prostate cancer cells through induction of actin aggregation and cofilin-actin rod formation.Cucurbitacin IIa: a novel class of anti-cancer drug inducing non-reversible actin aggregation and inhibiting survivin independent of JAK2/STAT3 phosphorylation.Direct interaction of Cucurbitacin E isolated from Alsomitra macrocarpa to actin filament.Cucurbitacin E suppresses cytokine expression in human Jurkat T cells through down-regulating the NF-κB signaling.Cucurbitacins: elucidation of their interactions with the cytoskeleton.The natural product cucurbitacin E inhibits depolymerization of actin filamentsIn vitro and in vivo anticancer properties of cucurbitacin isolated from Cayaponia racemosa.Janus kinase 2 and signal transducer and activator of transcription 3 activation is not essential for CCL3-, CCL5- or CCL8-induced chemotaxis.Natural products: a hope for glioblastoma patients.Focus on ADF/Cofilin: Beyond Actin Cytoskeletal Regulation
P2860
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P2860
Cucurbitacin E-induced disruption of the actin and vimentin cytoskeleton in prostate carcinoma cells.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh-hant
name
Cucurbitacin E-induced disrupt ...... n in prostate carcinoma cells.
@en
Cucurbitacin E-induced disrupt ...... n in prostate carcinoma cells.
@nl
type
label
Cucurbitacin E-induced disrupt ...... n in prostate carcinoma cells.
@en
Cucurbitacin E-induced disrupt ...... n in prostate carcinoma cells.
@nl
prefLabel
Cucurbitacin E-induced disrupt ...... n in prostate carcinoma cells.
@en
Cucurbitacin E-induced disrupt ...... n in prostate carcinoma cells.
@nl
P2093
P1476
Cucurbitacin E-induced disrupt ...... n in prostate carcinoma cells.
@en
P2093
P304
P356
10.1016/S0006-2952(96)00557-6
P407
P577
1996-11-01T00:00:00Z