Transgenic mice with a diverse human T cell antigen receptor repertoire.
about
TCR-Engineered T Cells Meet New Challenges to Treat Solid Tumors: Choice of Antigen, T Cell Fitness, and Sensitization of Tumor MilieuMelanoma: From Incurable Beast to a Curable Bet. The Success of ImmunotherapyGenetically modified T cells for the treatment of malignant diseaseT-cell receptor gene therapy--ready to go viral?How (specific) would like your T-cells today? Generating T-cell therapeutic function through TCR-gene transferEngineered T cells for cancer treatmentOncogene-targeting T cells reject large tumors while oncogene inactivation selects escape variants in mouse models of cancer.Relationship between Poor Immunogenicity of HLA-A2-Restricted Peptide Epitopes and Paucity of Naïve CD8(+) T-Cell Precursors in HLA-A2-Transgenic Mice.Design of T-cell receptor libraries with diverse binding properties to examine adoptive T-cell responses.Genetically engineered T cells for the treatment of cancer.A novel T cell receptor single-chain signaling complex mediates antigen-specific T cell activity and tumor controlGeneration of transgenic mice with megabase-sized human yeast artificial chromosomes by yeast spheroplast-embryonic stem cell fusion.High-throughput identification of antigen-specific TCRs by TCR gene capture.Targeting c-MYC with T-cellsProperties of MHC class I presented peptides that enhance immunogenicitySpecific roles of each TCR hemichain in generating functional chain-centric TCR.Trial Watch: Adoptive cell transfer immunotherapy.The determinants of tumour immunogenicity.Genomically humanized mice: technologies and promises.CD4(+) and CD8(+) TCRβ repertoires possess different potentials to generate extraordinarily high-avidity T cells.Engineered T cells for anti-cancer therapy.Enhancing adoptive T cell immunotherapy with microRNA therapeutics.Is cancer gene therapy an empty suit?Peptidomimetics: modifying peptides in the pursuit of better vaccines.Challenges in T cell receptor gene therapy.Adoptive immunotherapy for cancer.Adoptive cellular therapy: a race to the finish line.Human TCR-MHC coevolution after divergence from mice includes increased nontemplate-encoded CDR3 diversity.Immunotherapy for advanced melanoma: future directions.Adoptive Cellular Therapy (ACT) for Cancer Treatment.Altered peptide ligands revisited: vaccine design through chemically modified HLA-A2-restricted T cell epitopesA coreceptor-independent transgenic human TCR mediates anti-tumor and anti-self immunity in mice.Nonsegmental vitiligo and autoimmune mechanism.T-helper cell receptors from long-term survivors after telomerase cancer vaccination for use in adoptive cell therapy.T Cell Receptor Profiling in Type 1 Diabetes.Unbiased Identification of T-Cell Receptors Targeting Immunodominant Peptide-MHC Complexes for T-Cell Receptor Immunotherapy.HLA-B*39:06 Efficiently Mediates Type 1 Diabetes in a Mouse Model Incorporating Reduced Thymic Insulin Expression.Targeting Merkel cell carcinoma by engineered T cells specific to T-antigens of Merkel cell polyomavirus.
P2860
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P2860
Transgenic mice with a diverse human T cell antigen receptor repertoire.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
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2010年學術文章
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name
Transgenic mice with a diverse human T cell antigen receptor repertoire.
@en
Transgenic mice with a diverse human T cell antigen receptor repertoire.
@nl
type
label
Transgenic mice with a diverse human T cell antigen receptor repertoire.
@en
Transgenic mice with a diverse human T cell antigen receptor repertoire.
@nl
prefLabel
Transgenic mice with a diverse human T cell antigen receptor repertoire.
@en
Transgenic mice with a diverse human T cell antigen receptor repertoire.
@nl
P2093
P2860
P356
P1433
P1476
Transgenic mice with a diverse human T cell antigen receptor repertoire
@en
P2093
J Christoph Lampert
Jelena Popović
Liang-Ping Li
Thomas Blankenstein
Xiaojing Chen
P2860
P2888
P304
P356
10.1038/NM.2197
P407
P577
2010-08-08T00:00:00Z