Downregulation of protein phosphatase 2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis.
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Protein phosphatase 2A dysfunction in Alzheimer's diseaseTherapeutic benefits of a component of coffee in a rat model of Alzheimer's disease.Phosphoprotein phosphatase 2A: a novel druggable target for Alzheimer's diseaseNeuroprotective and anti-inflammatory properties of a coffee component in the MPTP model of Parkinson's diseaseProtein phosphatases and Alzheimer's diseaseThe biogenesis of active protein phosphatase 2A holoenzymes: a tightly regulated process creating phosphatase specificityCircumventing embryonic lethality with Lcmt1 deficiency: generation of hypomorphic Lcmt1 mice with reduced protein phosphatase 2A methyltransferase expression and defects in insulin signalingThe structural basis for tight control of PP2A methylation and function by LCMT-1.Silencing PP2A inhibitor by lenti-shRNA interference ameliorates neuropathologies and memory deficits in tg2576 mice.Genetic variation in the tau protein phosphatase-2A pathway is not associated with Alzheimer's disease risk.Role of protein phosphatases and mitochondria in the neuroprotective effects of estrogens.Cytoplasmic SET induces tau hyperphosphorylation through a decrease of methylated phosphatase 2A.Interaction between salt-inducible kinase 2 and protein phosphatase 2A regulates the activity of calcium/calmodulin-dependent protein kinase I and protein phosphatase methylesterase-1.Altered protein phosphatase 2A methylation and Tau phosphorylation in the young and aged brain of methylenetetrahydrofolate reductase (MTHFR) deficient mice.Epigenomics of Alzheimer's disease.Ferulic acid attenuates the injury-induced decrease of protein phosphatase 2A subunit B in ischemic brain injuryPhenylarsine oxide binding reveals redox-active and potential regulatory vicinal thiols on the catalytic subunit of protein phosphatase 2A.Up-regulation of inhibitors of protein phosphatase-2A in Alzheimer's disease.Tau is hyperphosphorylated at multiple sites in mouse brain in vivo after streptozotocin-induced insulin deficiencyThe protein phosphatase PP2A/Bα binds to the microtubule-associated proteins Tau and MAP2 at a motif also recognized by the kinase Fyn: implications for tauopathies.Curcumin treatment recovery the decrease of protein phosphatase 2A subunit B induced by focal cerebral ischemia in Sprague-Dawley ratsAcute administration of L-DOPA induces changes in methylation metabolites, reduced protein phosphatase 2A methylation, and hyperphosphorylation of Tau protein in mouse brain.Bridging the gap between protein carboxyl methylation and phospholipid methylation to understand glucose-stimulated insulin secretion from the pancreatic beta cell.Connecting cell-cycle activation to neurodegeneration in Drosophila.PP2A methylation controls sensitivity and resistance to β-amyloid-induced cognitive and electrophysiological impairments.GBA deficiency promotes SNCA/α-synuclein accumulation through autophagic inhibition by inactivated PPP2A.Protein phosphatase 2A contributes to the cardiac dysfunction induced by endotoxemia.Leucine carboxyl methyltransferase 1 (LCMT1)-dependent methylation regulates the association of protein phosphatase 2A and Tau protein with plasma membrane microdomains in neuroblastoma cellsPhysiological regulation of tau phosphorylation during hibernationEnhanced phosphatase activity attenuates α-synucleinopathy in a mouse modelPhosphorylated PP2A (tyrosine 307) is associated with Alzheimer neurofibrillary pathologyDysregulation of protein phosphatase 2A in parkinson disease and dementia with lewy bodies.Roles of phosphotase 2A in nociceptive signal processing.Tau as a therapeutic target for Alzheimer's diseaseMolecular and cellular mechanism of okadaic acid (OKA)-induced neurotoxicity: a novel tool for Alzheimer's disease therapeutic application.Effect of Pin1 or microtubule binding on dephosphorylation of FTDP-17 mutant TauGSK-3β is Dephosphorylated by PP2A in a Leu309 Methylation-Independent Manner.Polymeric alkylpyridinium salts permit intracellular delivery of human Tau in rat hippocampal neurons: requirement of Tau phosphorylation for functional deficits.Cytoskeleton as a Target of Quinolinic Acid Neurotoxicity: Insight from Animal Models.Regulation of protein phosphatase 2A methylation by LCMT1 and PME-1 plays a critical role in differentiation of neuroblastoma cells
P2860
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P2860
Downregulation of protein phosphatase 2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Downregulation of protein phos ...... lzheimer disease pathogenesis.
@en
Downregulation of protein phos ...... lzheimer disease pathogenesis.
@nl
type
label
Downregulation of protein phos ...... lzheimer disease pathogenesis.
@en
Downregulation of protein phos ...... lzheimer disease pathogenesis.
@nl
prefLabel
Downregulation of protein phos ...... lzheimer disease pathogenesis.
@en
Downregulation of protein phos ...... lzheimer disease pathogenesis.
@nl
P2093
P2860
P356
P1476
Downregulation of protein phos ...... Alzheimer disease pathogenesis
@en
P2093
Ampa Luangpirom
Christa Hladik
Estelle Sontag
Ingrid Mudrak
Lisa Montgomery
P2860
P304
P356
10.1093/JNEN/63.10.1080
P577
2004-10-01T00:00:00Z