Observation of Clinically Relevant Drug Interaction in Chimeric Mice with Humanized Livers: The Case of Valproic Acid and Carbapenem Antibiotics.

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Observation of Clinically Relevant Drug Interaction in Chimeric Mice with Humanized Livers: The Case of Valproic Acid and Carbapenem Antibiotics.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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name

Observation of Clinically Rele ...... id and Carbapenem Antibiotics.

@en

Observation of Clinically Rele ...... id and Carbapenem Antibiotics.

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type

Item

label

Observation of Clinically Rele ...... id and Carbapenem Antibiotics.

@en

Observation of Clinically Rele ...... id and Carbapenem Antibiotics.

@nl

prefLabel

Observation of Clinically Rele ...... id and Carbapenem Antibiotics.

@en

Observation of Clinically Rele ...... id and Carbapenem Antibiotics.

@nl

P1476

Observation of Clinically Rele ...... id and Carbapenem Antibiotics.

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P2093

Daisuke Nakai

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Eiko Suzuki

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Hiroshi Kuga

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Kan Chiba

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Kumiko Koyama

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Ryoya Goda

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P2860

New horizons for studying human hepatotropic infections

Using chimeric mice with humanized livers to predict human drug metabolism and a drug-drug interaction.

Assessment of chimeric mice with humanized livers in new drug development: generation of pharmacokinetics, metabolism and toxicity data for selecting the final candidate compound.

In vivo drug interactions of the teratogen thalidomide with midazolam: heterotropic cooperativity of human cytochrome P450 in humanized TK-NOG mice.

The nucleotide sequence of human acylamino acid-releasing enzyme.

Catabolism of intracellular N-terminal acetylated proteins: involvement of acylpeptide hydrolase and acylase.

In vivo modeling of human liver for pharmacological study using humanized mouse.

Novel pre-clinical methodologies for pharmacokinetic drug-drug interaction studies: spotlight on "humanized" animal models.

A comparison between genetically humanized and chimeric liver humanized mouse models for studies in drug metabolism and toxicity.

Clinical pharmacokinetics of valproic acid.

P2888

s13318-017-0413-2

P304

965-972

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P31

scholarly article

P356

10.1007/S13318-017-0413-2

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P433

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P478

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P577

2017-12-01T00:00:00Z

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P698

28447323

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P921

carbapenem antibiotic