The Transcriptional Activity of cAMP Response Element-binding Protein-binding Protein Is Modulated by the Latency Associated Nuclear Antigen of Kaposi's Sarcoma-associated Herpesvirus
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Protein interactions targeting the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus to cell chromosomesIdentification of a novel cellular transcriptional repressor interacting with the latent nuclear antigen of Kaposi's sarcoma-associated herpesvirusActivation of DNA Damage Response Induced by the Kaposi's Sarcoma-Associated Herpes VirusThe Modulation of Apoptotic Pathways by GammaherpesvirusesKaposi sarcoma herpes virus latency associated nuclear antigen protein release the G2/M cell cycle blocks by modulating ATM/ATR mediated checkpoint pathwayLANA binds to multiple active viral and cellular promoters and associates with the H3K4methyltransferase hSET1 complexKaposi's sarcoma-associated herpesvirus-encoded LANA can interact with the nuclear mitotic apparatus protein to regulate genome maintenance and segregation.Intrabodies targeting the Kaposi sarcoma-associated herpesvirus latency antigen inhibit viral persistence in lymphoma cells.Protein complexes associated with the Kaposi's sarcoma-associated herpesvirus-encoded LANA.Role of chromatin during herpesvirus infections.Molecular biology of KSHV in relation to AIDS-associated oncogenesis.Chromatin organization of gammaherpesvirus latent genomes.Kaposi's sarcoma-associated herpesvirus reactivation is regulated by interaction of latency-associated nuclear antigen with recombination signal sequence-binding protein Jkappa, the major downstream effector of the Notch signaling pathwayKaposi's sarcoma-associated herpesvirus-encoded LANA interacts with host KAP1 to facilitate establishment of viral latency.Kaposi sarcoma-associated herpesvirus latency-associated nuclear antigen inhibits interferon (IFN) beta expression by competing with IFN regulatory factor-3 for binding to IFNB promoterThe latency-associated nuclear antigen of rhesus monkey rhadinovirus inhibits viral replication through repression of Orf50/Rta transcriptional activation.Brd2/RING3 interacts with a chromatin-binding domain in the Kaposi's Sarcoma-associated herpesvirus latency-associated nuclear antigen 1 (LANA-1) that is required for multiple functions of LANA-1.Latency-associated nuclear antigen (LANA) cooperatively binds to two sites within the terminal repeat, and both sites contribute to the ability of LANA to suppress transcription and to facilitate DNA replication.A protein array screen for Kaposi's sarcoma-associated herpesvirus LANA interactors links LANA to TIP60, PP2A activity, and telomere shortening.Kaposi's sarcoma herpesvirus upregulates Aurora A expression to promote p53 phosphorylation and ubiquitylationRegulation and autoregulation of the promoter for the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus.Functional dissection of latency-associated nuclear antigen 1 of Kaposi's sarcoma-associated herpesvirus involved in latent DNA replication and transcription of terminal repeats of the viral genome.The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus supports latent DNA replication in dividing cells.Mitotic chromosome-binding activity of latency-associated nuclear antigen 1 is required for DNA replication from terminal repeat sequence of Kaposi's sarcoma-associated herpesvirusPhosphorylation of the chromatin binding domain of KSHV LANAKSHV LANA--the master regulator of KSHV latency.The latency-associated nuclear antigen homolog of herpesvirus saimiri inhibits lytic virus replication.Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen prolongs the life span of primary human umbilical vein endothelial cells.Molecular genetics of Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8) epidemiology and pathogenesis.Molecular biology of Kaposi's sarcoma-associated herpesvirus and related oncogenesisStructure and function of latency-associated nuclear antigen.The internal Kaposi's sarcoma-associated herpesvirus LANA regions exert a critical role on episome persistenceRibosomal protein S6 interacts with the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus.Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen reduces interleukin-8 expression in endothelial cells and impairs neutrophil chemotaxis by degrading nuclear p65.Diversity and evolution of chromatin proteins encoded by DNA viruses.ORF45-Mediated Prolonged c-Fos Accumulation Accelerates Viral Transcription during the Late Stage of Lytic Replication of Kaposi's Sarcoma-Associated Herpesvirus.Post-Translational Modifications of Kaposi's Sarcoma-Associated Herpesvirus Regulatory Proteins - SUMO and KSHVProtein arginine methyltransferase 1-directed methylation of Kaposi sarcoma-associated herpesvirus latency-associated nuclear antigen.Viral epigenetics.Activated Nrf2 Interacts with Kaposi's Sarcoma-Associated Herpesvirus Latency Protein LANA-1 and Host Protein KAP1 To Mediate Global Lytic Gene Repression.
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The Transcriptional Activity of cAMP Response Element-binding Protein-binding Protein Is Modulated by the Latency Associated Nuclear Antigen of Kaposi's Sarcoma-associated Herpesvirus
description
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
im Juni 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published in Journal of Biological Chemistry
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в червні 2001
@uk
name
The Transcriptional Activity o ...... Sarcoma-associated Herpesvirus
@en
The Transcriptional Activity o ...... Sarcoma-associated Herpesvirus
@nl
type
label
The Transcriptional Activity o ...... Sarcoma-associated Herpesvirus
@en
The Transcriptional Activity o ...... Sarcoma-associated Herpesvirus
@nl
prefLabel
The Transcriptional Activity o ...... Sarcoma-associated Herpesvirus
@en
The Transcriptional Activity o ...... Sarcoma-associated Herpesvirus
@nl
P2093
P2860
P356
P1476
The transcriptional activity o ...... sarcoma-associated herpesvirus
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P2093
P2860
P304
31016-31022
P356
10.1074/JBC.M102431200
P407
P577
2001-06-25T00:00:00Z