Fibroblast Growth Factor Receptors 1 and 2 Interact Differently with Heparin/Heparan Sulfate
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Heparan sulfate and heparin interactions with proteinsN-glycosylation of fibroblast growth factor receptor 1 regulates ligand and heparan sulfate co-receptor bindingFibroblast growth factors as tissue repair and regeneration therapeutics.Molecular mechanisms of fibroblast growth factor signaling in physiology and pathologyPanels of chemically-modified heparin polysaccharides and natural heparan sulfate saccharides both exhibit differences in binding to Slit and Robo, as well as variation between protein binding and cellular activityFibroblast growth factor 2 induced proliferation in osteoblasts and bone marrow stromal cells: a whole cell modelCompositional analysis of heparin/heparan sulfate interacting with fibroblast growth factor.fibroblast growth factor receptor complexesIncorporation of Sulfated Hyaluronic Acid Macromers into Degradable Hydrogel Scaffolds for Sustained Molecule Delivery.Spatio-temporally precise activation of engineered receptor tyrosine kinases by light.Structural specificity of heparin binding in the fibroblast growth factor family of proteins.Epithelial mesenchymal interactions, the ECM and limb development.Mannose phosphate isomerase regulates fibroblast growth factor receptor family signaling and glioma radiosensitivity.Heparan Sulfate Domains Required for Fibroblast Growth Factor 1 and 2 Signaling through Fibroblast Growth Factor Receptor 1c.Spatial and temporal expression of heparan sulfate in mouse development regulates FGF and FGF receptor assemblyMultivalent proteoglycan modulation of FGF mitogenic responses in perivascular cells.Fibroblast growth factors, old kids on the new block.Protein-induced supramolecular disassembly of amphiphilic polypeptide nanoassemblies.Differential sulfation remodelling of heparan sulfate by extracellular 6-O-sulfatases regulates fibroblast growth factor-induced boundary formation by glial cells: implications for glial cell transplantation.Heparan sulfotransferases Hs6st1 and Hs2st keep Erk in check for mouse corpus callosum development.Fibroblast growth factor-based signaling through synthetic heparan sulfate blocks copolymers studied using high cell density three-dimensional cell printingBiology of FGFRL1, the fifth fibroblast growth factor receptor.Mucopolysaccharidosis type I: current knowledge on its pathophysiological mechanisms.Heparan sulfate-related oligosaccharides in ternary complex formation with fibroblast growth factors 1 and 2 and their receptors.Cooperative dimerization of fibroblast growth factor 1 (FGF1) upon a single heparin saccharide may drive the formation of 2:2:1 FGF1.FGFR2c.heparin ternary complexes.Heparin/Heparan sulfate proteoglycans glycomic interactome in angiogenesis: biological implications and therapeutical use.Heparin modulates the mitogenic activity of fibroblast growth factor by inducing dimerization of its receptor. a 3D view by using NMR.Interactions of multiple heparin binding growth factors with neuropilin-1 and potentiation of the activity of fibroblast growth factor-2.Structural determinants of heparan sulphate modulation of GDNF signalling.Sulfated derivatives of Escherichia coli K5 polysaccharides as modulators of fibroblast growth factor signaling.The involvement of heparan sulfate (HS) in FGF1/HS/FGFR1 signaling complex.Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's beta-secretase.Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development.Control of fibroblast growth factor (FGF) 7- and FGF1-induced mitogenesis and downstream signaling by distinct heparin octasaccharide motifs.Multimers of the fibroblast growth factor (FGF)-FGF receptor-saccharide complex are formed on long oligomers of heparin.Intracellular trafficking in neurones and glia of fibroblast growth factor-2, fibroblast growth factor receptor 1 and heparan sulphate proteoglycans in the injured adult rat cerebral cortex.Analysis of the fibroblast growth factor receptor (FGFR) signalling network with heparin as coreceptor: evidence for the expansion of the core FGFR signalling network.
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P2860
Fibroblast Growth Factor Receptors 1 and 2 Interact Differently with Heparin/Heparan Sulfate
description
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
im Mai 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published in Journal of Biological Chemistry
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в травні 2002
@uk
name
Fibroblast Growth Factor Recep ...... y with Heparin/Heparan Sulfate
@en
Fibroblast Growth Factor Recep ...... y with Heparin/Heparan Sulfate
@nl
type
label
Fibroblast Growth Factor Recep ...... y with Heparin/Heparan Sulfate
@en
Fibroblast Growth Factor Recep ...... y with Heparin/Heparan Sulfate
@nl
prefLabel
Fibroblast Growth Factor Recep ...... y with Heparin/Heparan Sulfate
@en
Fibroblast Growth Factor Recep ...... y with Heparin/Heparan Sulfate
@nl
P2860
P356
P1476
Fibroblast growth factor recep ...... of a ternary signaling complex
@en
P2093
Andrew K Powell
Jeremy E Turnbull
P2860
P304
28554-28563
P356
10.1074/JBC.M111754200
P407
P577
2002-05-28T00:00:00Z