Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2

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Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2

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im Oktober 2018 veröffentlichter wissenschaftlicher Artikel

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scientific article published on 01 October 2018

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wetenschappelijk artikel

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наукова стаття, опублікована в жовтні 2018

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Ciprofloxacin impairs mitochon ...... inhibition of Topoisomerase 2

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Ciprofloxacin impairs mitochon ...... inhibition of Topoisomerase 2

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Ciprofloxacin impairs mitochon ...... inhibition of Topoisomerase 2

@en

Ciprofloxacin impairs mitochon ...... inhibition of Topoisomerase 2

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Ciprofloxacin impairs mitochon ...... inhibition of Topoisomerase 2

@en

Ciprofloxacin impairs mitochon ...... inhibition of Topoisomerase 2

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P1476

Ciprofloxacin impairs mitochon ...... inhibition of Topoisomerase 2

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Anu Hangas

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Koit Aasumets

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Mika Paloheinä

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Nina J Kekäläinen

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Steffi Goffart

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P2860

The mitochondrial transcription and packaging factor Tfam imposes a U-turn on mitochondrial DNA

Twinkle mutations associated with autosomal dominant progressive external ophthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling

Dual localization of human DNA topoisomerase IIIalpha to mitochondria and nucleus

Targeted disruption of the mouse topoisomerase I gene by camptothecin selection

Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice

Effects of conditional depletion of topoisomerase II on cell cycle progression in mammalian cells.

Damage to mitochondria of cultured human skin fibroblasts photosensitized by fluoroquinolones.

The RepE initiator is a double-stranded and single-stranded DNA-binding protein that forms an atypical open complex at the onset of replication of plasmid pAMbeta 1 from Gram-positive bacteria.

Supercoiling, knotting and replication fork reversal in partially replicated plasmids.

Pharmacokinetic profiles of high-dose intravenous ciprofloxacin in severe sepsis. The Baragwanath Ciprofloxacin Study Group.

P304

9625-9636

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scholarly article

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10.1093/NAR/GKY793

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English

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P478

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Joachim M Gerhold

Jaakko Pohjoismäki

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2018-10-01T00:00:00Z

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P698

30169847

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P921

mitochondrial DNA

mitochondrion

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6182158

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