about
Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects14-3-3 Proteins regulate exonuclease 1-dependent processing of stalled replication forksVisualization of recombination-mediated damage bypass by template switching.Error-free DNA damage tolerance and sister chromatid proximity during DNA replication rely on the Polα/Primase/Ctf4 ComplexNew histone supply regulates replication fork speed and PCNA unloading.Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition.Topoisomerase I poisoning results in PARP-mediated replication fork reversal.A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development.Pathogen-Induced TLR4-TRIF Innate Immune Signaling in Hematopoietic Stem Cells Promotes Proliferation but Reduces Competitive Fitness.Rad51-dependent DNA structures accumulate at damaged replication forks in sgs1 mutants defective in the yeast ortholog of BLM RecQ helicase.Exo1 processes stalled replication forks and counteracts fork reversal in checkpoint-defective cells.Noncanonical Mismatch Repair as a Source of Genomic Instability in Human Cells.Exo1 competes with repair synthesis, converts NER intermediates to long ssDNA gaps, and promotes checkpoint activation.CDC7 kinase promotes MRE11 fork processing, modulating fork speed and chromosomal breakage
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description
researcher
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wetenschapper
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հետազոտող
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name
Massimo Lopes
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Massimo Lopes
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Massimo Lopes
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Massimo Lopes
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type
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Massimo Lopes
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Massimo Lopes
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Massimo Lopes
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Massimo Lopes
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prefLabel
Massimo Lopes
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Massimo Lopes
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Massimo Lopes
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Massimo Lopes
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P106
P1153
7202369169
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P31
P496
0000-0003-3847-8133