about
Lipopolysaccharide and tumor necrosis factor regulate Parkin expression via nuclear factor-kappa B.Age-related changes in regulator of G-protein signaling (RGS)-10 expression in peripheral and central immune cells may influence the risk for age-related degeneration.Quantitative analysis of the detergent-insoluble brain proteome in frontotemporal lobar degeneration using SILAC internal standardsProgranulin does not bind tumor necrosis factor (TNF) receptors and is not a direct regulator of TNF-dependent signaling or bioactivity in immune or neuronal cells.Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson's disease.Regulation of microglia effector functions by tumor necrosis factor signaling.Peripheral administration of the selective inhibitor of soluble tumor necrosis factor (TNF) XPro®1595 attenuates nigral cell loss and glial activation in 6-OHDA hemiparkinsonian rats.Chronic psychological stress and high-fat high-fructose diet disrupt metabolic and inflammatory gene networks in the brain, liver, and gut and promote behavioral deficits in mice.Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice.Stool immune profiles evince gastrointestinal inflammation in Parkinson's disease.
P50
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P50
name
Jianjun Chang
@ast
Jianjun Chang
@en
Jianjun Chang
@nl
type
label
Jianjun Chang
@ast
Jianjun Chang
@en
Jianjun Chang
@nl
prefLabel
Jianjun Chang
@ast
Jianjun Chang
@en
Jianjun Chang
@nl