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Guidelines for the use and interpretation of assays for monitoring autophagyGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Ubiquitin is phosphorylated by PINK1 to activate parkinShort mitochondrial ARF triggers Parkin/PINK1-dependent mitophagyUSP9x-mediated deubiquitination of EFA6 regulates de novo tight junction assembly.BAG5 inhibits parkin and enhances dopaminergic neuron degenerationUbiquilin recruits Eps15 into ubiquitin-rich cytoplasmic aggregates via a UIM-UBL interactionStructure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of NeuroprotectionParkin-mediated monoubiquitination of the PDZ protein PICK1 regulates the activity of acid-sensing ion channelsThe three 'P's of mitophagy: PARKIN, PINK1, and post-translational modificationsSH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitinationStructure of parkin reveals mechanisms for ubiquitin ligase activationParkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality controlCyberinfrastructure for Open Science at the Montreal Neurological InstituteParkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brainStructure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation.Long-term potentiation in isolated dendritic spines.Methamphetamine-induced degeneration of dopaminergic neurons involves autophagy and upregulation of dopamine synthesis.USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkinLRRK2 localizes to endosomes and interacts with clathrin-light chains to limit Rac1 activation.The E3 ubiquitin ligase parkin is recruited to the 26 S proteasome via the proteasomal ubiquitin receptor Rpn13Ataxin-3 deubiquitination is coupled to Parkin ubiquitination via E2 ubiquitin-conjugating enzyme.Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitmentWengen, the sole tumour necrosis factor receptor in Drosophila, collaborates with moesin to control photoreceptor axon targeting during development.Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system.Ataxin-3 and its e3 partners: implications for machado-joseph disease.Parkin- and PINK1-Dependent Mitophagy in Neurons: Will the Real Pathway Please Stand Up?A new pathway for mitochondrial quality control: mitochondrial-derived vesicles.Endocytic membrane trafficking and neurodegenerative disease.Defending the mitochondria: The pathways of mitophagy and mitochondrial-derived vesicles.Pre-synaptic and post-synaptic localization of EphA4 and EphB2 in adult mouse forebrain.Isolation of human proteasomes and putative proteasome-interacting proteins using a novel affinity chromatography method.A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling.Normal biogenesis and cycling of empty synaptic vesicles in dopamine neurons of vesicular monoamine transporter 2 knockout mice.The Machado-Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability.USP8 and PARK2/parkin-mediated mitophagy.The Neuroprotective Role of Protein Quality Control in Halting the Development of Alpha-Synuclein Pathology.Expanding horizons at Big Sky. Symposium on ubiquitin and signaling.Presenting mitochondrial antigens: PINK1, Parkin and MDVs steal the show.EphA4 is localized in clathrin-coated and synaptic vesicles in adult mouse brain.
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description
researcher
@en
name
Edward A. Fon
@en
Edward A. Fon
@nl
type
label
Edward A. Fon
@en
Edward A. Fon
@nl
altLabel
E A Fon
@en
E Fon
@en
E. A. Fon
@en
E. Fon
@en
Edward A Fon
@en
Edward Fon
@en
Fon E
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Fon E. A.
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Fon E.
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Fon EA
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prefLabel
Edward A. Fon
@en
Edward A. Fon
@nl
P106
P21
P31
P496
0000-0002-5520-6239