Crystal structure of the high-affinity Na+,K+-ATPase-ouabain complex with Mg2+ bound in the cation binding site
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Simulation of alcohol action upon a detailed Purkinje neuron model and a simpler surrogate model that runs >400 times fasterSpecialized Functional Diversity and Interactions of the Na,K-ATPaseInsights into the Pathology of the α3 Na(+)/K(+)-ATPase Ion Pump in Neurological Disorders; Lessons from Animal ModelsThe physiological and clinical importance of sodium potassium ATPase in cardiovascular diseasesRegulation of renal function and structure by the signaling Na/K-ATPaseStructure of the Na,K-ATPase regulatory protein FXYD2b in micelles: Implications for membrane–water interfacial argininesCrystal structure of Na+, K(+)-ATPase in the Na(+)-bound stateCardiac glycoside activities link Na(+)/K(+) ATPase ion-transport to breast cancer cell migration via correlative SARInfluence of Sugar Amine Regiochemistry on Digitoxigenin Neoglycoside Anticancer Activity21-Benzylidene digoxin: a proapoptotic cardenolide of cancer cells that up-regulates Na,K-ATPase and epithelial tight junctionsNovel stereoselective bufadienolides reveal new insights into the requirements for Na(+), K(+)-ATPase inhibition by cardiotonic steroidsCell signaling associated with Na(+)/K(+)-ATPase: activation of phosphatidylinositide 3-kinase IA/Akt by ouabain is independent of Src.Systematic comparison of molecular conformations of H+,K+-ATPase reveals an important contribution of the A-M2 linker for the luminal gating.Structure and mechanism of Zn2+-transporting P-type ATPases.Spherical Oligo-Silicic Acid SOSA Disclosed as Possible Endogenous Digitalis-Like Factor.Structures and characterization of digoxin- and bufalin-bound Na+,K+-ATPase compared with the ouabain-bound complexA structural rearrangement of the Na+/K+-ATPase traps ouabain within the external ion permeation pathway.Thermal proteome profiling monitors ligand interactions with cellular membrane proteins.Mechanism of potassium ion uptake by the Na(+)/K(+)-ATPase.Proteasome Inhibition Contributed to the Cytotoxicity of Arenobufagin after Its Binding with Na, K-ATPase in Human Cervical Carcinoma HeLa Cells.Transcriptional regulators of Na,K-ATPase subunits.Digoxin derivatives with selectivity for the α2β3 isoform of Na,K-ATPase potently reduce intraocular pressure.A quantitative shRNA screen identifies ATP1A1 as a gene that regulates cytotoxicity by aurilide B.Tuning of the Na,K-ATPase by the beta subunit.The selectivity of the Na(+)/K(+)-pump is controlled by binding site protonation and self-correcting occlusion.Convallatoxin-Induced Reduction of Methionine Import Effectively Inhibits Human Cytomegalovirus Infection and Replication.Membrane Lipid Microenvironment Modulates Thermodynamic Properties of the Na+-K+-ATPase in Branchial and Intestinal Epithelia in Euryhaline Fish In vivo.Cholesterol as a co-solvent and a ligand for membrane proteins.Targeting Na⁺/K⁺ -translocating adenosine triphosphatase in cancer treatment.Conserved molecular mechanisms underlying the effects of small molecule xenobiotic chemotherapeutics on cells.Basal Glutathionylation of Na,K-ATPase α-Subunit Depends on Redox Status of Cells during the Enzyme BiosynthesisComputer modelling reveals new conformers of the ATP binding loop of Na+/K+-ATPase involved in the transphosphorylation process of the sodium pump.Structures, chemotaxonomic significance, cytotoxic and Na(+),K(+)-ATPase inhibitory activities of new cardenolides from Asclepias curassavica.Cytotoxic effects of the cardenolide convallatoxin and its Na,K-ATPase regulation.Metal-Catalyzed Asymmetric Michael Addition in Natural Product Synthesis.Na⁺i,K⁺i-Dependent and -Independent Signaling Triggered by Cardiotonic Steroids: Facts and Artifacts.Protein Interaction and Na/K-ATPase-Mediated Signal Transduction.Inversions and adaptation to the plant toxin ouabain shape DNA sequence variation within and between chromosomal inversions of Drosophila subobscura.Inhibition of Non Canonical HIV-1 Tat Secretion Through the Cellular Na+,K+-ATPase Blocks HIV-1 Infection.Binding of ouabain and marinobufagenin leads to different structural changes in Na,K-ATPase and depends on the enzyme conformation.
P2860
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P2860
Crystal structure of the high-affinity Na+,K+-ATPase-ouabain complex with Mg2+ bound in the cation binding site
description
2013 nî lūn-bûn
@nan
2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Crystal structure of the high- ...... und in the cation binding site
@ast
Crystal structure of the high- ...... und in the cation binding site
@en
Crystal structure of the high- ...... und in the cation binding site
@nl
type
label
Crystal structure of the high- ...... und in the cation binding site
@ast
Crystal structure of the high- ...... und in the cation binding site
@en
Crystal structure of the high- ...... und in the cation binding site
@nl
prefLabel
Crystal structure of the high- ...... und in the cation binding site
@ast
Crystal structure of the high- ...... und in the cation binding site
@en
Crystal structure of the high- ...... und in the cation binding site
@nl
P2860
P50
P3181
P356
P1476
Crystal structure of the high- ...... und in the cation binding site
@en
P2093
Mette Laursen
P2860
P304
10958-10963
P3181
P356
10.1073/PNAS.1222308110
P407
P577
2013-06-17T00:00:00Z