TLS, EWS and TAF15: a model for transcriptional integration of gene expression
about
Alternative 3'-end processing of long noncoding RNA initiates construction of nuclear paraspecklesFUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitmentFUS/TLS is a co-activator of androgen receptor in prostate cancer cellsAbundant FUS-immunoreactive pathology in neuronal intermediate filament inclusion diseaseALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear importA new subtype of frontotemporal lobar degeneration with FUS pathologyImmunoprecipitation and mass spectrometry defines an extensive RBM45 protein-protein interaction networkRoles of RNA-Binding Proteins in DNA Damage ResponseMutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosisMutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response.Ewing Sarcoma, an enigmatic malignancy of likely progenitor cell origin, driven by transcription factor oncogenic fusions.De novo truncating FUS gene mutation as a cause of sporadic amyotrophic lateral sclerosis.Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma.FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations.Proteomic analysis of mitotic RNA polymerase II reveals novel interactors and association with proteins dysfunctional in disease.Myxoid liposarcoma-associated EWSR1-DDIT3 selectively represses osteoblastic and chondrocytic transcription in multipotent mesenchymal cells.Fus gene mutations in familial and sporadic amyotrophic lateral sclerosis.Functions of FUS/TLS from DNA repair to stress response: implications for ALS.Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granulesSubnuclear compartmentalization of transiently expressed polyadenylated pri-microRNAs: processing at transcription sites or accumulation in SC35 foci.A cell-based method for screening RNA-protein interactions: identification of constitutive transport element-interacting proteins.Quantitative profiling of in vivo-assembled RNA-protein complexes using a novel integrated proteomic approachThe RNA-binding protein fused in sarcoma (FUS) functions downstream of poly(ADP-ribose) polymerase (PARP) in response to DNA damageYeast one-hybrid screen of a thymus epithelial library identifies ZBTB7A as a regulator of thymic insulin expressionALS-associated FUS mutations result in compromised FUS alternative splicing and autoregulation.A network of RNA and protein interactions in Fronto Temporal Dementia.A fruitful endeavor: modeling ALS in the fruit flyNormal and functional TP53 in genetically stable myxoid/round cell liposarcoma.Altered RNA metabolism and amyotrophic lateral sclerosisALS mutations in TLS/FUS disrupt target gene expression.fus/TLS orchestrates splicing of developmental regulators during gastrulation.A large-scale functional screen identifies Nova1 and Ncoa3 as regulators of neuronal miRNA functionSimiRa: A tool to identify coregulation between microRNAs and RNA-binding proteins.Structural delineation of stem-loop RNA binding by human TAF15 protein.Nuclear carrier and RNA-binding proteins in frontotemporal lobar degeneration associated with fused in sarcoma (FUS) pathological changes.Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis.The RRM domain of human fused in sarcoma protein reveals a non-canonical nucleic acid binding site.Y-box binding protein-1 regulates cell proliferation and is associated with clinical outcomes of osteosarcomaALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules
P2860
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P2860
TLS, EWS and TAF15: a model for transcriptional integration of gene expression
description
2006 nî lūn-bûn
@nan
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
TLS, EWS and TAF15: a model for transcriptional integration of gene expression
@ast
TLS, EWS and TAF15: a model for transcriptional integration of gene expression
@en
TLS, EWS and TAF15: a model for transcriptional integration of gene expression
@nl
type
label
TLS, EWS and TAF15: a model for transcriptional integration of gene expression
@ast
TLS, EWS and TAF15: a model for transcriptional integration of gene expression
@en
TLS, EWS and TAF15: a model for transcriptional integration of gene expression
@nl
prefLabel
TLS, EWS and TAF15: a model for transcriptional integration of gene expression
@ast
TLS, EWS and TAF15: a model for transcriptional integration of gene expression
@en
TLS, EWS and TAF15: a model for transcriptional integration of gene expression
@nl
P2093
P356
P1476
TLS, EWS and TAF15: a model for transcriptional integration of gene expression
@en
P2093
Geoffrey G Hicks
Kendra L Cann
Warren J Law
P356
10.1093/BFGP/ELL015
P407
P577
2006-03-01T00:00:00Z