Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus
about
Recognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccinationMolecular mechanisms of autoimmunity triggered by microbial infection.Toll-like receptors in systemic lupus erythematosus: potential targets for therapeutic interventionB cells take the front seat: dysregulated B cell signals orchestrate loss of tolerance and autoantibody productionIntracellular nucleic acid sensors and autoimmunityRNA mediated Toll-like receptor stimulation in health and diseaseTLRs and interferons: a central paradigm in autoimmunityMultiple Roles for B-Lymphocytes in Sjogren's SyndromeSexual dimorphism in autoimmunityContribution of dendritic cells to the autoimmune pathology of systemic lupus erythematosusInterferons and viruses: an evolutionary arms race of molecular interactionsThe receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunityApoptotic cell responses in the splenic marginal zone: a paradigm for immunologic reactions to apoptotic antigens with implications for autoimmunityBANK1 controls CpG-induced IL-6 secretion via a p38 and MNK1/2/eIF4E translation initiation pathwayNucleic acid scavenging polymers inhibit extracellular DNA-mediated innate immune activation without inhibiting anti-viral responsesEstrogen receptor alpha modulates Toll-like receptor signaling in murine lupusSpontaneous autoimmunity in mice that carry an IghV partial transgene: a required arginine in VHCDR3.Glomerular autoimmune multicomponents of human lupus nephritis in vivo: α-enolase and annexin AI.In Vivo Chronic Stimulation Unveils Autoreactive Potential of Wiskott-Aldrich Syndrome Protein-Deficient B Cells.Impaired autoimmune T helper 17 cell responses following DNA vaccination against rat experimental autoimmune encephalomyelitis.Host-pathogen interactions: a biological rendez-vous of the infectious nonself and danger models?Antiviral defense: interferons and beyondInduction of IgG3 to LPS via Toll-like receptor 4 co-stimulation.Bacterial amyloid curli acts as a carrier for DNA to elicit an autoimmune response via TLR2 and TLR9Dosage of X-linked Toll-like receptor 8 determines gender differences in the development of systemic lupus erythematosus.Lupus and proliferative nephritis are PAD4 independent in murine models.The adaptor molecule MyD88 activates PI-3 kinase signaling in CD4+ T cells and enables CpG oligodeoxynucleotide-mediated costimulation.IFN regulatory factor 5 is required for disease development in the FcgammaRIIB-/-Yaa and FcgammaRIIB-/- mouse models of systemic lupus erythematosusTLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupusAltered B cell signalling in autoimmunity.Contribution of IRF5 in B cells to the development of murine SLE-like disease through its transcriptional control of the IgG2a locus.Dendritic cells in systemic lupus erythematosusToll-like receptor signaling: a potential link among rheumatoid arthritis, systemic lupus, and atherosclerosis.Nucleic acid sensing receptors in systemic lupus erythematosus: development of novel DNA- and/or RNA-like analogues for treating lupus.Treatment with a toll-like receptor inhibitory GpG oligonucleotide delays and attenuates lupus nephritis in NZB/W mice.Toll-like receptor 7 (TLR7) modulates anti-nucleosomal autoantibody isotype and renal complement deposition in mice exposed to syngeneic late apoptotic cells.Silencing of renal DNaseI in murine lupus nephritis imposes exposure of large chromatin fragments and activation of Toll like receptors and the Clec4e.Toll-like receptor 9 enhances nephritogenic immunity and glomerular leukocyte recruitment, exacerbating experimental crescentic glomerulonephritis.Pathogenic and Epiphenomenal Anti-DNA Antibodies in SLE.B cell-intrinsic TLR7 signaling is essential for the development of spontaneous germinal centers.
P2860
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P2860
Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus
@ast
Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus
@en
type
label
Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus
@ast
Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus
@en
prefLabel
Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus
@ast
Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus
@en
P2093
P2860
P356
P1476
Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus
@en
P2093
Mark J Shlomchik
Michael Kashgarian
Richard A Flavell
Sean R Christensen
Shizuo Akira
P2860
P304
P356
10.1084/JEM.20050338
P407
P577
2005-07-01T00:00:00Z