Prion-like propagation of protein aggregation and related therapeutic strategies. - Test2 - elhamkhani - TriplyDB

Prion-like propagation of protein aggregation and related therapeutic strategies.

Prion-like propagation of protein aggregation and related therapeutic strategies.

http://www.wikidata.org/entity/Q36983208

about

Network dysfunction in Alzheimer's disease: refining the disconnection hypothesis Ectosomes: a new mechanism for non-exosomal secretion of tau protein.Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite-like aggregates.Chronic exposure to cerebrospinal fluid of multiple system atrophy in neuroblastoma and glioblastoma cells induces cytotoxicity via ER stress and autophagy activation Human prion protein-induced autophagy flux governs neuron cell damage in primary neuron cells.Sensitive Detection of Proteopathic Seeding Activity with FRET Flow Cytometry Propagation of tau pathology in Alzheimer's disease: identification of novel therapeutic targets.The aggregation of mutant p53 produces prion-like properties in cancer.Invited review: Animal models of tauopathies and their implications for research/translation into the clinic.Key Points Concerning Amyloid Infectivity and Prion-Like Neuronal Invasion Potential Pathways of Abnormal Tau and α-Synuclein Dissemination in Sporadic Alzheimer's and Parkinson's Diseases.The olfactory bulb as the entry site for prion-like propagation in neurodegenerative diseases.Tau seeding activity begins in the transentorhinal/entorhinal regions and anticipates phospho-tau pathology in Alzheimer's disease and PART.

P2860

Q26995432-AEB18C42-84AA-4BFC-81AD-D0D0053A0230 Q35196319-70A938C4-EFBA-43AC-A399-9F5D66EB4D8C Q35215169-02A42CB7-C033-4AF5-9470-8CF9590547DC Q35955278-FAB53144-4A8E-471D-BE1E-A323774817FB Q35996444-89F18CC7-6B78-49DD-903D-2289A00881A8 Q36408405-683292FC-340D-44DA-9BA8-DA218267A000 Q38154973-F201A5E8-07C1-4B72-9802-652CC87E4949 Q38186535-E0094592-D402-4329-861C-129A855C92DD Q38271896-56579EC4-636B-4FD7-B84E-86044C4EE41F Q38826332-37E3FC4E-A26E-4F22-9921-200DB29A4989 Q38942540-9B36F0DB-B206-49E8-9AFA-2A9AD3A58110 Q39052041-F8B9A38F-3206-4711-A4E7-DEE87D32F487 Q55405326-7B0FB0B4-8727-4EAC-8A00-15C457397011

P2860

Prion-like propagation of protein aggregation and related therapeutic strategies.

http://www.wikidata.org/entity/Q36983208

description

2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

Prion-like propagation of protein aggregation and related therapeutic strategies.

@en

type

label

Prion-like propagation of protein aggregation and related therapeutic strategies.

@en

prefLabel

Prion-like propagation of protein aggregation and related therapeutic strategies.

@en

P1433

Q36983208-6610C264-CD01-4B94-A678-5AF4652AED53

P1476

Q36983208-ADB9FF70-4957-46BF-B265-EB4BC2615CC3

P2093

Q36983208-3251318F-62C2-443F-ACAB-FE4D3F3AD010

Q36983208-ED912B83-7D29-4DDA-9EBD-A3C1232B8615

P2860

Q36983208-01697D75-E930-4749-8443-F7171F0E4E43

Q36983208-02F283F1-453B-4576-A5C3-3B9C36559040

Q36983208-03541849-8EFA-4D04-8734-1D6646713C68

Q36983208-03E918BA-A847-4AD5-89DC-EE6D15829438

Q36983208-0705431B-8F9D-42BA-A86D-5EC56F3B5B2F

Q36983208-088DDBD8-5446-47FA-A148-F9204F9D48BA

Q36983208-08E278E1-7994-40B2-89A6-BE6509274E3D

Q36983208-09BBC73B-6E61-487A-990F-94BA21FD3599

Q36983208-09CDC94D-0882-45CF-BE15-9352C36F088E

Q36983208-0B589119-3A8B-45FA-95E3-33369A421D41

P2888

Q36983208-A7124A53-B57B-47CE-92D1-CE16FF7D0E87

P304

Q36983208-898CA158-2146-4092-98AE-953BACD5E18F

P31

Q36983208-B5FDC770-E476-4899-B687-4E5675F5844B

P356

Q36983208-5FD30F7F-54BA-4FF2-AF91-F7B3E898EAE9

P433

Q36983208-57518E49-2F2D-4CE7-AFD2-D9D236210ABE

P478

Q36983208-32013D82-51D0-42FB-A262-C763558B0B14

P577

Q36983208-C072FA67-A8A4-46B0-B8E4-DEAEEF300770

P5875

Q36983208-10D717E6-26C1-434D-AA56-F510E6CDB04B

P698

Q36983208-79706FB8-A740-401F-B8A5-3A13D8986756

P921

Q36983208-86E93B8D-4818-48FE-BC64-05A7AF255BEC

P932

Q36983208-F45BD562-49E6-4230-9931-001F75A0BD90

P356

S13311-013-0196-3

P1433

Neurotherapeutics

P1476

Prion-like propagation of protein aggregation and related therapeutic strategies.

@en

P2093

Marc I Diamond

http://www.w3.org/2001/XMLSchema#string

Sarah K Kaufman

http://www.w3.org/2001/XMLSchema#string

P2860

Superoxide dismutase 1 and tgSOD1 mouse spinal cord seed fibrils, suggesting a propagative cell death mechanism in amyotrophic lateral sclerosis

Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells

Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture

A seeding reaction recapitulates intracellular formation of Sarkosyl-insoluble transactivation response element (TAR) DNA-binding protein-43 inclusions

α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells.

P2888

s13311-013-0196-3

P304

371-382

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1007/S13311-013-0196-3

http://www.w3.org/2001/XMLSchema#string

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

10

http://www.w3.org/2001/XMLSchema#string

P577

2013-07-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

242017219

http://www.w3.org/2001/XMLSchema#string

P698

23801258

http://www.w3.org/2001/XMLSchema#string

P921

Prion protein family

P932

3701767

http://www.w3.org/2001/XMLSchema#string