Research in motion: the enigma of Parkinson's disease pathology spread.
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Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in miceThe synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementiaTransfer of host-derived α synuclein to grafted dopaminergic neurons in ratα-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells.A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced deathTransmission and spreading of tauopathy in transgenic mouse brainInclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synucleinThe Dual Function of Reactive Oxygen/Nitrogen Species in Bioenergetics and Cell Death: The Role of ATP SynthaseThe role of macropinocytosis in the propagation of protein aggregation associated with neurodegenerative diseasesAdult neural stem cells: an endogenous tool to repair brain injury?Multiple system atrophy: a clinical and neuropathological perspectiveFeatures of alpha-synuclein that could explain the progression and irreversibility of Parkinson's diseaseInflammation and α-synuclein's prion-like behavior in Parkinson's disease--is there a link?Propagation of alpha-synuclein pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies.Alpha-synuclein spreading in Parkinson's diseaseNicotinamide, NAD(P)(H), and Methyl-Group Homeostasis Evolved and Became a Determinant of Ageing Diseases: Hypotheses and Lessons from PellagraIdentification of Neurexophilin 3 as a Novel Supportive Factor for Survival of Induced Pluripotent Stem Cell-Derived Dopaminergic ProgenitorsEnvironmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in miceLysosomal-associated protein multispanning transmembrane 5 gene (LAPTM5) is associated with spontaneous regression of neuroblastomasPrion-like transmission of protein aggregates in neurodegenerative diseasesConsiderations on the role of environmental toxins in idiopathic Parkinson's disease pathophysiologyTowards translational therapies for multiple system atrophyCell-based therapies for Parkinson's disease: past, present, and futureUbiquitin/proteasome pathway impairment in neurodegeneration: therapeutic implicationsAstrocytes and therapeutics for Parkinson's disease.Disentangling the relationship between lewy bodies and nigral neuronal loss in Parkinson's disease.Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity.Anterograde degeneration along the visual pathway after optic nerve injuryPathogenesis of Parkinson disease--the gut-brain axis and environmental factors.Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice.Progressive aggregation of alpha-synuclein and selective degeneration of lewy inclusion-bearing neurons in a mouse model of parkinsonism.E46K human alpha-synuclein transgenic mice develop Lewy-like and tau pathology associated with age-dependent, detrimental motor impairmentNeural stem cells: historical perspective and future prospects.Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus.The Interplay between Alpha-Synuclein Clearance and SpreadingFrontal cortex neuropathology in dementia pugilistica.Studies of lipopolysaccharide effects on the induction of α-synuclein pathology by exogenous fibrils in transgenic mice.Distinct clinical and neuropathological features of G51D SNCA mutation cases compared with SNCA duplication and H50Q mutationDistribution of α-synuclein in the spinal cord and dorsal root ganglia in an autopsy cohort of elderly persons.Tianma modulates blood vessel tonicity
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Research in motion: the enigma of Parkinson's disease pathology spread.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 04 September 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Research in motion: the enigma of Parkinson's disease pathology spread.
@en
Research in motion: the enigma of Parkinson's disease pathology spread.
@nl
type
label
Research in motion: the enigma of Parkinson's disease pathology spread.
@en
Research in motion: the enigma of Parkinson's disease pathology spread.
@nl
prefLabel
Research in motion: the enigma of Parkinson's disease pathology spread.
@en
Research in motion: the enigma of Parkinson's disease pathology spread.
@nl
P2093
P921
P356
P1476
Research in motion: the enigma of Parkinson's disease pathology spread.
@en
P2093
Janice L Holton
Olle Lindvall
Tamas Revesz
P2888
P304
P356
10.1038/NRN2477
P407
P577
2008-09-04T00:00:00Z