The Battle of San Domingo was a naval battle of the Napoleonic Wars fought on 6 February 1806 between squadrons of French and British ships of the line off the southern coast of the French-occupied Spanish colonial Captaincy General of Santo Domingo (San Domingo in contemporary British English) in the Caribbean. The French squadron, under Vice-Admiral Corentin Urbain Leissègues in the 120-gun Impérial, had sailed from Brest in December 1805, one of two squadrons intending to raid British trade routes as part of the Atlantic campaign of 1806.