DNA-binding transcription factor activity
Usage guidance: Most DNA-binding transcription factors do not have enzymatic activity. The presence of specific DNA-binding domains known to be present in DNA-binding transcription factors (HOX, GATA etc) should be used to help decide whether a protein is a DNA binding transcription factor or a coregulator. If a protein has an enzymatic activity (for example, ubiquitin ligase, histone acetyl transferase) and no known DNA binding domain, consider annotating to GO:0003712 transcription coregulator activity. Special care should be taken with proteins containing zinc fingers, Myb/SANT and ARID domains, since only a subset of proteins containing these domains directly and selectively bind to regulatory DNA motifs in cis-regulatory regions.
annotatedSource
DNA-binding transcription factor activity
Usage guidance: Most DNA-binding transcription factors do not have enzymatic activity. The presence of specific DNA-binding domains known to be present in DNA-binding transcription factors (HOX, GATA etc) should be used to help decide whether a protein is a DNA binding transcription factor or a coregulator. If a protein has an enzymatic activity (for example, ubiquitin ligase, histone acetyl transferase) and no known DNA binding domain, consider annotating to GO:0003712 transcription coregulator activity. Special care should be taken with proteins containing zinc fingers, Myb/SANT and ARID domains, since only a subset of proteins containing these domains directly and selectively bind to regulatory DNA motifs in cis-regulatory regions.
definition
A transcription regulator acti ...... and include bacterial operons.
term tracker item
created_by
creation_date
2010-10-21T04:37:54Z
has_alternative_id
GO:0000130
GO:0001071
GO:0001130
GO:0001131
GO:0001151
GO:0001199
GO:0001204
has_broad_synonym
nucleic acid binding transcription factor activity
transcription factor activity
has_exact_synonym
DNA binding transcription factor activity
gene-specific transcription factor activity
sequence-specific DNA binding transcription factor activity
has_narrow_synonym
bacterial-type DNA binding transcription factor activity
bacterial-type RNA polymerase ...... transcription factor activity
bacterial-type RNA polymerase ...... transcription factor activity
bacterial-type RNA polymerase ...... sequence-specific DNA binding
bacterial-type RNA polymerase ...... sequence-specific DNA binding
metal ion regulated sequence-s ...... transcription factor activity
metal ion regulated sequence-specific DNA binding transcription factor activity
sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity
transcription factor activity, ...... gion sequence-specific binding
transcription factor activity, ...... sequence-specific DNA binding
has_obo_namespace
molecular_function
id
GO:0003700
in_subset
type
comment
Usage guidance: Most DNA-bindi ...... ifs in cis-regulatory regions.
label
DNA-binding transcription factor activity