Structural basis for the activation of PPARgamma by oxidized fatty acids - Wikidata - thesis-toulmin - TriplyDB

Structural basis for the activation of PPARgamma by oxidized fatty acids

Structural basis for the activation of PPARgamma by oxidized fatty acids

http://www.wikidata.org/entity/Q27653525

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Docosahexaenoic acid-derived neuroprotectin D1 induces neuronal survival via secretase- and PPARγ-mediated mechanisms in Alzheimer's disease models Selected Extracts of Chinese Herbal Medicines: Their Effect on NF-κB, PPARα and PPARγ and the Respective Bioactive Compounds Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review Computer-aided discovery, validation, and mechanistic characterization of novel neolignan activators of peroxisome proliferator-activated receptor gamma Honokiol: a non-adipogenic PPARγ agonist from nature Abscisic acid regulates inflammation via ligand-binding domain-independent activation of peroxisome proliferator-activated receptor gamma Endogenous Generation and Signaling Actions of Omega-3 Fatty Acid Electrophilic Derivatives Mechanisms of gene regulation by fatty acids Collagen Induced Arthritis in DBA/1J Mice Associates with Oxylipin Changes in Plasma 15-Lipoxygenase metabolites of α-linolenic acid, [13-(S)-HPOTrE and 13-(S)-HOTrE], mediate anti-inflammatory effects by inactivating NLRP3 inflammasome.Megalin/LRP2 expression is induced by peroxisome proliferator-activated receptor -alpha and -gamma: implications for PPARs' roles in renal function Atomic structure of mutant PPARgamma LBD complexed with 15d-PGJ2: novel modulation mechanism of PPARgamma/RXRalpha function by covalently bound ligands Activation of RXR–PPAR heterodimers by organotin environmental endocrine disruptors Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures The nuclear receptor PPARγ individually responds to serotonin- and fatty acid-metabolites Revealing a steroid receptor ligand as a unique PPARγ agonist Identification and Mechanism of 10-Carbon Fatty Acid as Modulating Ligand of Peroxisome Proliferator-activated Receptors Medium Chain Fatty Acids Are Selective Peroxisome Proliferator Activated Receptor (PPAR) γ Activators and Pan-PPAR Partial Agonists Identification of the antibiotic ionomycin as an unexpected peroxisome proliferator-activated receptor γ (PPARγ) ligand with a unique binding mode and effective glucose-lowering activity in a mouse model of diabetes Identification of a new hormone-binding site on the surface of thyroid hormone receptor Resolvin D1 binds human phagocytes with evidence for proresolving receptors Redox-dependent anti-inflammatory signaling actions of unsaturated fatty acids Redox signaling in inflammation: interactions of endogenous electrophiles and mitochondria in cardiovascular disease Aberrant soluble epoxide hydrolase and oxylipin levels in a porcine arteriovenous graft stenosis model Dietary α-eleostearic acid ameliorates experimental inflammatory bowel disease in mice by activating peroxisome proliferator-activated receptor-γ Epidermis-type lipoxygenase 3 regulates adipocyte differentiation and peroxisome proliferator-activated receptor gamma activity Modulation of membrane lipid composition and homeostasis in salmon hepatocytes exposed to hypoxia and perfluorooctane sulfonamide, given singly or in combination Oxidative Stress and Metabolic Perturbations in Wooden Breast Disorder in Chickens ω-6 lipids regulate PPAR turnover via reciprocal switch between PGC-1 alpha and ubiquitination CHARMM Force Field Parameterization of Peroxisome Proliferator-Activated Receptor γ Ligands Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics.Virtual Screening as a Technique for PPAR Modulator Discovery.Novel lipid mediators and resolution mechanisms in acute inflammation: to resolve or not?Electrophilic nitro-fatty acids: anti-inflammatory mediators in the vascular compartment.Inhibitor SBFI26 suppresses the malignant progression of castration-resistant PC3-M cells by competitively binding to oncogenic FABP5 Covalent peroxisome proliferator-activated receptor gamma adduction by nitro-fatty acids: selective ligand activity and anti-diabetic signaling actions.Targeting Peroxisome Proliferator-Activated Receptors Using Thiazolidinediones: Strategy for Design of Novel Antidiabetic Drugs Diosgenin relieves goiter via the inhibition of thyrocyte proliferation in a mouse model of Graves' disease.Betulinic acid is a PPARγ antagonist that improves glucose uptake, promotes osteogenesis and inhibits adipogenesis.

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Structural basis for the activation of PPARgamma by oxidized fatty acids

http://www.wikidata.org/entity/Q27653525

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2008 nî lūn-bûn

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2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Structural basis for the activation of PPARgamma by oxidized fatty acids

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Structural basis for the activation of PPARgamma by oxidized fatty acids

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Structural basis for the activation of PPARgamma by oxidized fatty acids

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type

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Structural basis for the activation of PPARgamma by oxidized fatty acids

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Structural basis for the activation of PPARgamma by oxidized fatty acids

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Structural basis for the activation of PPARgamma by oxidized fatty acids

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Structural basis for the activation of PPARgamma by oxidized fatty acids

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Structural basis for the activation of PPARgamma by oxidized fatty acids

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Structural basis for the activation of PPARgamma by oxidized fatty acids

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Nature Structural & Molecular Biology

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Structural basis for the activation of PPARgamma by oxidized fatty acids

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Attila Szanto

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Kush Amin

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Toshimasa Itoh

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Yuka Inaba

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P2860

Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma

Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors

Structure of the PPARalpha and -gamma ligand binding domain in complex with AZ 242; ligand selectivity and agonist activation in the PPAR family

Insights into the mechanism of partial agonism: crystal structures of the peroxisome proliferator-activated receptor gamma ligand-binding domain in the complex with two enantiomeric ligands

Partial agonists activate PPARgamma using a helix 12 independent mechanism

The three-dimensional structure of the human Pi class glutathione transferase P1-1 in complex with the inhibitor ethacrynic acid and its glutathione conjugate

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

Coot: model-building tools for molecular graphics

Version 1.2 of the Crystallography and NMR system

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924-931

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scholarly article

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884139

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10.1038/NSMB.1474

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9

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15

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Balint L. Balint

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2008-09-01T00:00:00Z

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23951872

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1022891712

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19172745

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2939985

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