Gap junctional hemichannel-mediated ATP release and hearing controls in the inner ear
about
Mutation of the ATP-gated P2X(2) receptor leads to progressive hearing loss and increased susceptibility to noise.Identification and characterization of pannexin expression in the mammalian cochleaGap junctionsAberrant Cx26 hemichannels and keratitis-ichthyosis-deafness syndrome: insights into syndromic hearing lossCellular and Deafness Mechanisms Underlying Connexin Mutation-Induced Hearing Loss - A Common Hereditary Deafness.Fibro-vascular coupling in the control of cochlear blood flowThe role of pannexin hemichannels in inflammation and regenerationConnexin30 null and conditional connexin26 null mice display distinct pattern and time course of cellular degeneration in the cochleaAltered inhibition of Cx26 hemichannels by pH and Zn2+ in the A40V mutation associated with keratitis-ichthyosis-deafness syndromeThe human deafness-associated connexin 30 T5M mutation causes mild hearing loss and reduces biochemical coupling among cochlear non-sensory cells in knock-in mice.Connexin43 hemichannels contributes to the disassembly of cell junctions through modulation of intracellular oxidative statusUnmyelinated type II afferent neurons report cochlear damage.Reduced Connexin26 in the Mature Cochlea Increases Susceptibility to Noise-Induced Hearing Lossin MiceDifferentiating connexin hemichannels and pannexin channels in cellular ATP release.Pannexin1 channels dominate ATP release in the cochlea ensuring endocochlear potential and auditory receptor potential generation and hearing.Hearing loss caused by a P2RX2 mutation identified in a MELAS family with a coexisting mitochondrial 3243AG mutation.Recognition and control of the progression of age-related hearing loss.Extracellular gentamicin reduces the activity of connexin hemichannels and interferes with purinergic Ca(2+) signaling in HeLa cells.Rho-family GTPases modulate Ca(2+) -dependent ATP release from astrocytes.Inner ear supporting cells: rethinking the silent majority.ATP activates P2X receptors to mediate gap junctional coupling in the cochlea.The cochlear CRF signaling systems and their mechanisms of action in modulating cochlear sensitivity and protection against trauma.Calcium signaling in the cochlea - Molecular mechanisms and physiopathological implications.BAAV mediated GJB2 gene transfer restores gap junction coupling in cochlear organotypic cultures from deaf Cx26Sox10Cre mice.A corticotropin-releasing factor system expressed in the cochlea modulates hearing sensitivity and protects against noise-induced hearing lossConnexin30 deficiency causes instrastrial fluid-blood barrier disruption within the cochlear stria vascularis.Differential expression of P2Y receptors in the rat cochlea during development.Purinergic signaling in cochleovestibular hair cells and afferent neurons.Adenosine and the auditory system.ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca2+ signals across the inner earModulation of outer hair cell electromotility by cochlear supporting cells and gap junctionsRecent findings and emerging questions in cochlear noise injury.Gap-junction channels dysfunction in deafness and hearing loss.Purinergic signaling in the inner ear.Developmental regulation of spontaneous activity in the Mammalian cochlea.ATP-mediated cell-cell signaling in the organ of Corti: the role of connexin channels.ATP-mediated potassium recycling in the cochlear supporting cells.Basal release of ATP: an autocrine-paracrine mechanism for cell regulation.A novel DFNB1 deletion allele supports the existence of a distant cis-regulatory region that controls GJB2 and GJB6 expression.Pathogenic connexin-31 forms constitutively active hemichannels to promote necrotic cell death
P2860
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P2860
Gap junctional hemichannel-mediated ATP release and hearing controls in the inner ear
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Gap junctional hemichannel-mediated ATP release and hearing controls in the inner ear
@ast
Gap junctional hemichannel-mediated ATP release and hearing controls in the inner ear
@en
type
label
Gap junctional hemichannel-mediated ATP release and hearing controls in the inner ear
@ast
Gap junctional hemichannel-mediated ATP release and hearing controls in the inner ear
@en
prefLabel
Gap junctional hemichannel-mediated ATP release and hearing controls in the inner ear
@ast
Gap junctional hemichannel-mediated ATP release and hearing controls in the inner ear
@en
P2093
P2860
P356
P1476
Gap junctional hemichannel-mediated ATP release and hearing controls in the inner ear
@en
P2093
Carrie R Fleming
Hong-Bo Zhao
P2860
P304
18724-18729
P356
10.1073/PNAS.0506481102
P407
P577
2005-12-12T00:00:00Z