Inhibition of the TRPC5 ion channel protects the kidney filter
about
PodocytesCalcium, TRPC channels, and regulation of the actin cytoskeleton in podocytes: towards a future of targeted therapiesNovel in vivo techniques to visualize kidney anatomy and function.Transient receptor potential canonical 4 and 5 proteins as targets in cancer therapeuticsTRPC6 channel as an emerging determinant of the podocyte injury susceptibility in kidney diseasesRenal autoregulation in health and diseaseIntravital imaging of podocyte calcium in glomerular injury and disease.Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli.The Role of Angiotensin II in Glomerular Volume Dynamics and Podocyte Calcium Handling.Structural analysis of how podocytes detach from the glomerular basement membrane under hypertrophic stressReview series: The cell biology of renal filtration.Canonical transient receptor potential 4 and its small molecule modulators.Gq signaling causes glomerular injury by activating TRPC6.Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channelsEffects of stromal interaction molecule 1 or Orai1 overexpression on the associated proteins and permeability of podocytes.Sirtuin1 Maintains Actin Cytoskeleton by Deacetylation of Cortactin in Injured Podocytes.Single-channel Analysis and Calcium Imaging in the Podocytes of the Freshly Isolated GlomeruliIL-34 mediates acute kidney injury and worsens subsequent chronic kidney disease.Role of renal TRP channels in physiology and pathologyDrug discovery in focal and segmental glomerulosclerosisCalcium-permeable ion channels in the kidney.Transient receptor potential canonical 5 (TRPC5) protects against pain and vascular inflammation in arthritis and joint inflammation.How many Achilles' heels does a podocyte have? An update on podocyte biology.The importance of podocyte adhesion for a healthy glomerulus.Nox and renal disease.Human genetics of nephrotic syndrome and the quest for precision medicine.Podocytes and the quest for precision medicines for kidney diseases.Changes in podocyte TRPC channels evoked by plasma and sera from patients with recurrent FSGS and by putative glomerular permeability factors.Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels.Targeting the podocyte cytoskeleton: from pathogenesis to therapy in proteinuric kidney disease.Podocyte-actin dynamics in health and disease.Blocking peptides and molecular mimicry as treatment for kidney disease.Natural and synthetic flavonoid modulation of TRPC5 channels.Pharmacological inhibition of FSGS-related TRPC6 gain of function mutants by semisynthetic larixol-derived compounds.Cell-free measurements of brightness of fluorescently labeled antibodies.Nephrin Tyrosine Phosphorylation Is Required to Stabilize and Restore Podocyte Foot Process Architecture.TRPM2 mediates ischemic kidney injury and oxidant stress through RAC1.Melanocortin 1 receptor agonist protects podocytes through catalase and RhoA activation.A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models.The Hippo pathway regulator KIBRA promotes podocyte injury by inhibiting YAP signaling and disrupting actin cytoskeletal dynamics.
P2860
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P2860
Inhibition of the TRPC5 ion channel protects the kidney filter
description
2013 nî lūn-bûn
@nan
2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Inhibition of the TRPC5 ion channel protects the kidney filter
@ast
Inhibition of the TRPC5 ion channel protects the kidney filter
@en
type
label
Inhibition of the TRPC5 ion channel protects the kidney filter
@ast
Inhibition of the TRPC5 ion channel protects the kidney filter
@en
prefLabel
Inhibition of the TRPC5 ion channel protects the kidney filter
@ast
Inhibition of the TRPC5 ion channel protects the kidney filter
@en
P2093
P2860
P356
P1476
Inhibition of the TRPC5 ion channel protects the kidney filter
@en
P2093
Anna Greka
Antonio Riccio
Astrid Weins
Constantine Tarabanis
Corey R Hopkins
Dequan Tian
Hanna Wallentin
Lisa Buvall
Philip Castonguay
P2860
P304
P356
10.1172/JCI71165
P407
P577
2013-11-15T00:00:00Z