A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates
about
Recent developments in using mechanistic cardiac modelling for drug safety evaluationComputational Approaches to Understanding the Role of Fibroblast-Myocyte Interactions in Cardiac ArrhythmogenesisMechanisms of ventricular arrhythmias: from molecular fluctuations to electrical turbulenceStochastic spontaneous calcium release events trigger premature ventricular complexes by overcoming electrotonic loadSpiral-wave dynamics in a mathematical model of human ventricular tissue with myocytes and fibroblasts.Spatially Discordant Alternans and Arrhythmias in Tachypacing-Induced Cardiac Myopathy in Transgenic LQT1 Rabbits: The Importance of IKs and Ca2+ CyclingFilament Dynamics during Simulated Ventricular Fibrillation in a High-Resolution Rabbit HeartElectrophysiology of Heart Failure Using a Rabbit Model: From the Failing Myocyte to Ventricular Fibrillation.Nonequilibrium arrhythmic states and transitions in a mathematical model for diffuse fibrosis in human cardiac tissueSimulation Methods and Validation Criteria for Modeling Cardiac Ventricular ElectrophysiologySodium current reduction unmasks a structure-dependent substrate for arrhythmogenesis in the normal ventriclesFormation of spatially discordant alternans due to fluctuations and diffusion of calciumA study of early afterdepolarizations in a model for human ventricular tissue.Simulation of the undiseased human cardiac ventricular action potential: model formulation and experimental validationPopulation of computational rabbit-specific ventricular action potential models for investigating sources of variability in cellular repolarisationSynergy between CaMKII substrates and β-adrenergic signaling in regulation of cardiac myocyte Ca(2+) handling.Sudden cardiac death prediction and prevention: report from a National Heart, Lung, and Blood Institute and Heart Rhythm Society Workshop.Synchronization of chaotic early afterdepolarizations in the genesis of cardiac arrhythmias.Modeling effects of L-type ca(2+) current and na(+)-ca(2+) exchanger on ca(2+) trigger flux in rabbit myocytes with realistic T-tubule geometriesTransmural IK(ATP) heterogeneity as a determinant of activation rate gradient during early ventricular fibrillation: mechanistic insights from rabbit ventricular models.Pro- and antiarrhythmic effects of ATP-sensitive potassium current activation on reentry during early afterdepolarization-mediated arrhythmiasA multiscale computational model of spatially resolved calcium cycling in cardiac myocytes: from detailed cleft dynamics to the whole cell concentration profiles.Mechanisms of vortices termination in the cardiac muscle.Local Gradients in Electrotonic Loading Modulate the Local Effective Refractory Period: Implications for Arrhythmogenesis in the Infarct Border Zone.Ionic mechanisms for electrical heterogeneity between rabbit Purkinje fiber and ventricular cells.Automatically generated, anatomically accurate meshes for cardiac electrophysiology problems.Development of an anatomically detailed MRI-derived rabbit ventricular model and assessment of its impact on simulations of electrophysiological function.Generation of histo-anatomically representative models of the individual heart: tools and applicationEffects of maximal sodium and potassium conductance on the stability of Hodgkin-Huxley model.Interplay of voltage and Ca-dependent inactivation of L-type Ca current.Irregularly appearing early afterdepolarizations in cardiac myocytes: random fluctuations or dynamical chaos?So little source, so much sink: requirements for afterdepolarizations to propagate in tissue.Simulating photon scattering effects in structurally detailed ventricular models using a Monte Carlo approach.Nonlinear and Stochastic Dynamics in the HeartData-based theoretical identification of subcellular calcium compartments and estimation of calcium dynamics in cardiac myocytes.Mechanisms and determinants of ultralong action potential duration and slow rate-dependence in cardiac myocytes.Genesis of phase 3 early afterdepolarizations and triggered activity in acquired long-QT syndrome.Chaos in the genesis and maintenance of cardiac arrhythmias.Coupled Iterated Map Models of Action Potential Dynamics in a One-dimensional Cable of Cardiac Cells.The role of mitochondria for the regulation of cardiac alternans.
P2860
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P2860
A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
A rabbit ventricular action po ...... dynamics at rapid heart rates
@ast
A rabbit ventricular action po ...... dynamics at rapid heart rates
@en
type
label
A rabbit ventricular action po ...... dynamics at rapid heart rates
@ast
A rabbit ventricular action po ...... dynamics at rapid heart rates
@en
prefLabel
A rabbit ventricular action po ...... dynamics at rapid heart rates
@ast
A rabbit ventricular action po ...... dynamics at rapid heart rates
@en
P2093
P2860
P1433
P1476
A rabbit ventricular action po ...... dynamics at rapid heart rates
@en
P2093
Alain Karma
Alan Garfinkel
Aman Mahajan
Daisuke Sato
James N Weiss
Lai-Hua Xie
Ming-Jim Yang
Peng-Sheng Chen
Riccardo Olcese
P2860
P304
P356
10.1529/BIOPHYSJ.106.98160
P407
P577
2008-01-01T00:00:00Z