about
P688
ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathwayCell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeresChk2 activation dependence on Nbs1 after DNA damageRescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunitMre11 complex and DNA replication: linkage to E2F and sites of DNA synthesisCritical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpointATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complexATM-dependent phosphorylation of ATF2 is required for the DNA damage responseNibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndromeThe hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage responseRAD50 and NBS1 form a stable complex functional in DNA binding and tetheringThe mismatch repair system is required for S-phase checkpoint activationRecruitment of NBS1 into PML oncogenic domains via interaction with SP100 proteinMRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length controlNijmegen breakage syndrome disease protein and MRE11 at PML nuclear bodies and meiotic telomeresThe involvement of the Mre11/Rad50/Nbs1 complex in the generation of G-overhangs at human telomeres
P921
Q22253899-883F7E55-226C-493F-9D0E-44E443A198B1Q22254585-890861A7-B22C-4743-8DEB-49278C070F1FQ24291406-F8DD44C1-A6A1-4656-8A81-32E3748C1D69Q24291434-A43106C2-B002-4030-8B78-89918EC0C44CQ24291532-9B6DDEA2-8FB3-4962-A3B5-2EED6C018B32Q24292703-A6A85FA5-5FFE-43EF-A294-C0247ABE3030Q24298863-B494D6CA-F591-456F-8A8E-765B3619D3DEQ24303597-B6ED36AA-2484-4F8A-9A39-AC93DA9E5163Q24316811-CC54DB49-91C8-405A-8B50-54FFA1C4F90BQ24316950-0582B110-F73B-4CE8-B146-2C7EEC4B3C2EQ24317537-094B7976-8FBB-4920-B07A-72B6A20276C8Q24321503-EDEB8305-69A2-450F-8965-8FF59FA07703Q24324163-959A2C40-6F5E-4575-ADE0-60AEF7495402Q28115619-62C48B3C-09C3-4B95-BBEE-0DE5F5DB11C2Q28116555-3633C04A-1E18-43CE-AA4C-190CA339AD40Q28118408-12495B6B-55DB-4766-AD4A-3EC05055E483
P921
description
humanes Protein
@de
mammalian protein found in Homo sapiens
@en
menselijk eiwit
@nl
protein
@id
protein
@sv
proteinë
@sq
proteína de mamífero encontrada en Homo sapiens
@es
protèin
@ace
protéine humaine
@fr
بروتين بشري
@ar
name
Nibrin
@en
Nibrin
@nl
Nibrina
@es
Нибрин
@ru
type
label
Nibrin
@en
Nibrin
@nl
Nibrina
@es
Нибрин
@ru
altLabel
NBN
@en
NNBN
@es
Nijmegen breakage syndrome 1 (nibrin)
@en
Nijmegen breakage syndrome protein 1
@en
Proteína 1 del síndrome de Nimega
@es
cell cycle regulatory protein p95
@en
nibrin
@en
p95 protein of the MRE11/RAD50 complex
@en
proteína reguladora del ciclo celular p95
@es
prefLabel
Nibrin
@en
Nibrin
@nl
Nibrina
@es
Нибрин
@ru
P361
P527
P637
P680
P681
P682
P705
P352
P637
P31
P352
P527
P637
NP_001019859
XP_011515347
XP_011515348
XP_016868949
XP_016868951
XP_024302931
XP_024302932
XP_024302933
P680
P681
P682
P702
P703
P705
ENSP00000265433
ENSP00000379551
ENSP00000386924
ENSP00000428252
ENSP00000428717
ENSP00000429971
ENSP00000430983
ENSP00000484487