Golgi-localizing, gamma-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their Vps27p/Hrs/STAM (VHS) domains
about
The trihelical bundle subdomain of the GGA proteins interacts with multiple partners through overlapping but distinct sitesVHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargoEndofin recruits TOM1 to endosomesRecognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 gamma-sigma1 and AP-3 delta-sigma3 hemicomplexesSNX1 defines an early endosomal recycling exit for sortilin and mannose 6-phosphate receptorsIdentification of a novel ubiquitin binding site of STAM1 VHS domain by NMR spectroscopyConsortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexinsInteractions of GGA3 with the ubiquitin sorting machineryRole of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptorCharacterization of sorCS1, an alternatively spliced receptor with completely different cytoplasmic domains that mediate different trafficking in cellsDivalent interaction of the GGAs with the Rabaptin-5-Rabex-5 complex.ADP-ribosylation factor (ARF) interaction is not sufficient for yeast GGA protein function or localization.GGA proteins associate with Golgi membranes through interaction between their GGAH domains and ADP-ribosylation factorsAutoinhibition of the ligand-binding site of GGA1/3 VHS domains by an internal acidic cluster-dileucine motif.Adaptins: the final recountWNK4 enhances the degradation of NCC through a sortilin-mediated lysosomal pathwaySTAM proteins bind ubiquitinated proteins on the early endosome via the VHS domain and ubiquitin-interacting motifThe human Vps29 retromer component is a metallo-phosphoesterase for a cation-independent mannose 6-phosphate receptor substrate peptideMammalian GGAs act together to sort mannose 6-phosphate receptorsAnalysis of Gga null mice demonstrates a non-redundant role for mammalian GGA2 during developmentStructural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domainsStructural basis for recognition of acidic-cluster dileucine sequence by GGA1Crystal structure of GGA2 VHS domain and its implication in plasticity in the ligand binding pocketStructure of the GAT domain of human GGA1: A syntaxin amino-terminal domain fold in an endosomal trafficking adaptorEpsins: adaptors in endocytosis?Interaction of the cation-dependent mannose 6-phosphate receptor with GGA proteinsMannose 6-phosphate receptors: new twists in the taleThe sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA bindingTollip and Tom1 form a complex and recruit ubiquitin-conjugated proteins onto early endosomesThe trans-Golgi network accessory protein p56 promotes long-range movement of GGA/clathrin-containing transport carriers and lysosomal enzyme sorting.Visualization of TGN to endosome trafficking through fluorescently labeled MPR and AP-1 in living cellsMorphology and dynamics of clathrin/GGA1-coated carriers budding from the trans-Golgi networkFunctional characterization of protein-sorting machineries at the trans-Golgi network in Drosophila melanogasterGGA1 interacts with the adaptor protein AP-1 through a WNSF sequence in its hinge region.GAT (GGA and Tom1) domain responsible for ubiquitin binding and ubiquitination.Impact of genetic background on neonatal lethality of Gga2 gene-trap mice.Activation of membrane NADPH oxidase associated with lysosome-targeted acid sphingomyelinase in coronary endothelial cells.HMMerThread: detecting remote, functional conserved domains in entire genomes by combining relaxed sequence-database searches with fold recognition.Identification of acidic dileucine signals in LRP9 that interact with both GGAs and AP-1/AP-2VHS domain -- a longshoreman of vesicle lines.
P2860
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P2860
Golgi-localizing, gamma-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their Vps27p/Hrs/STAM (VHS) domains
description
2001 nî lūn-bûn
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2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
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2001年の論文
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2001年学术文章
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2001年学术文章
@zh-cn
2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年學術文章
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name
Golgi-localizing, gamma-adapti ...... Vps27p/Hrs/STAM (VHS) domains
@ast
Golgi-localizing, gamma-adapti ...... Vps27p/Hrs/STAM (VHS) domains
@en
Golgi-localizing, gamma-adapti ...... Vps27p/Hrs/STAM (VHS) domains
@en-gb
Golgi-localizing, gamma-adapti ...... Vps27p/Hrs/STAM (VHS) domains
@nl
type
label
Golgi-localizing, gamma-adapti ...... Vps27p/Hrs/STAM (VHS) domains
@ast
Golgi-localizing, gamma-adapti ...... Vps27p/Hrs/STAM (VHS) domains
@en
Golgi-localizing, gamma-adapti ...... Vps27p/Hrs/STAM (VHS) domains
@en-gb
Golgi-localizing, gamma-adapti ...... Vps27p/Hrs/STAM (VHS) domains
@nl
prefLabel
Golgi-localizing, gamma-adapti ...... Vps27p/Hrs/STAM (VHS) domains
@ast
Golgi-localizing, gamma-adapti ...... Vps27p/Hrs/STAM (VHS) domains
@en
Golgi-localizing, gamma-adapti ...... Vps27p/Hrs/STAM (VHS) domains
@en-gb
Golgi-localizing, gamma-adapti ...... Vps27p/Hrs/STAM (VHS) domains
@nl
P2093
P2860
P356
P1476
Golgi-localizing, gamma-adapti ...... Vps27p/Hrs/STAM (VHS) domains
@en
P2093
P2860
P304
P356
10.1074/JBC.C100218200
P407
P577
2001-07-27T00:00:00Z