p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2
about
Microrna-221 and microrna-222 modulate differentiation and maturation of skeletal muscle cellsSrc kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasmPhosphorylation of p27Kip1 by JAK2 directly links cytokine receptor signaling to cell cycle controlKnockdown of protein tyrosine phosphatase SHP-1 inhibits G1/S progression in prostate cancer cells through the regulation of components of the cell-cycle machineryRSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility.Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferationUnderstanding pRb: toward the necessary development of targeted treatments for retinoblastomaMechanism of p27 Unfolding for CDK2 Reactivation.A novel mutation in β integrin reveals an integrin-mediated interaction between the extracellular matrix and cki-1/p27KIP1Role of T198 modification in the regulation of p27(Kip1) protein stability and functionBrk/Protein tyrosine kinase 6 phosphorylates p27KIP1, regulating the activity of cyclin D-cyclin-dependent kinase 4A novel RING finger protein, Znf179, modulates cell cycle exit and neuronal differentiation of P19 embryonal carcinoma cellsCDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction pointThe selective RNA-binding protein quaking I (QKI) is necessary and sufficient for promoting oligodendroglia differentiationCommon and specific roles of the related CDK inhibitors p27 and p57 revealed by a knock-in mouse modelA dynamic view of domain-motif interactions.Reciprocal regulation of metabolic and signaling pathways.Long non-coding RNA UCA1 promotes breast tumor growth by suppression of p27 (Kip1)Mitogenic regulation of p27(Kip1) gene is mediated by AP-1 transcription factors.Upstream molecular signaling pathways of p27(Kip1) expression: effects of 4-hydroxytamoxifen, dexamethasone, and retinoic acids.Inhibition of PI-3K restores nuclear p27Kip1 expression in a mouse model of Kras-driven lung cancer.Multisite phosphorylation provides an effective and flexible mechanism for switch-like protein degradation.Chemical genetics approach to restoring p27Kip1 reveals novel compounds with antiproliferative activity in prostate cancer cellsRapamycin regulates endothelial cell migration through regulation of the cyclin-dependent kinase inhibitor p27Kip1.Role of BCR-ABL-Y177-mediated p27kip1 phosphorylation and cytoplasmic localization in enhanced proliferation of chronic myeloid leukemia progenitors.Deregulated estrogen receptor alpha and p53 heterozygosity collaborate in the development of mammary hyperplasia.Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus.Simultaneous siRNA targeting of Src and downstream signaling molecules inhibit tumor formation and metastasis of a human model breast cancer cell line.The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cellsSrc, a potential target for overcoming trastuzumab resistance in HER2-positive breast carcinoma.Trihydrophobin 1 phosphorylation by c-Src regulates MAPK/ERK signaling and cell migrationDasatinib induces autophagic cell death in human ovarian cancer.Dasatinib inhibits the growth of molecularly heterogeneous myeloid leukemias.Phosphorylation and subcellular localization of p27Kip1 regulated by hydrogen peroxide modulation in cancer cellsHuman cytomegalovirus infection dysregulates the canonical Wnt/β-catenin signaling pathway.p27: a barometer of signaling deregulation and potential predictor of response to targeted therapies.The regulatory loop of COMP1 and HNF-4-miR-150-p27 in various signaling pathways.Antiproliferative effect of sulindac in colonic neoplasia prevention: role of COOH-terminal Src kinase.p27(Kip1), a double-edged sword in Shh-mediated medulloblastoma: Tumor accelerator and suppressor.Silencing kinase-interacting stathmin gene enhances erlotinib sensitivity by inhibiting Ser¹⁰ p27 phosphorylation in epidermal growth factor receptor-expressing breast cancer.
P2860
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P2860
p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2
@ast
p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2
@en
p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2
@en-gb
p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2
@nl
type
label
p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2
@ast
p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2
@en
p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2
@en-gb
p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2
@nl
prefLabel
p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2
@ast
p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2
@en
p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2
@en-gb
p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2
@nl
P2093
P2860
P3181
P1433
P1476
p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2
@en
P2093
Angel Arnaout
Cheng-Keat Tan
Harriette Kahn
Isabel Chu
Joyce Slingerland
Ludger Hengst
Wedad Hanna
P2860
P304
P3181
P356
10.1016/J.CELL.2006.11.049
P407
P577
2007-01-26T00:00:00Z