PKCdelta regulates collagen-induced platelet aggregation through inhibition of VASP-mediated filopodia formation
about
The small GTPase Rif is dispensable for platelet filopodia generation in micePKCalpha regulates platelet granule secretion and thrombus formation in miceThe role of filopodia in the recognition of nanotopographies.Genetic analysis of the role of protein kinase Ctheta in platelet function and thrombus formationDifferential roles of the PKC novel isoforms, PKCdelta and PKCepsilon, in mouse and human platelets.Platelet protein kinase C-theta deficiency with human RUNX1 mutation: PRKCQ is a transcriptional target of RUNX1.Functional roles of VASP phosphorylation in the regulation of chemotaxis and osmotic stress responseThrombin and collagen induce a feedback inhibitory signaling pathway in platelets involving dissociation of the catalytic subunit of protein kinase A from an NFkappaB-IkappaB complex.Protein kinase C alpha and beta are positive regulators of thrombus formation in vivo in a zebrafish (Danio rerio) model of thrombosis.Signaling during platelet adhesion and activationGinsenoside-Rp1 inhibits platelet activation and thrombus formation via impaired glycoprotein VI signalling pathway, tyrosine phosphorylation and MAPK activation.Therapeutic potential for protein kinase C inhibitor in vascular restenosis.Insights into dietary flavonoids as molecular templates for the design of anti-platelet drugsProtein kinase C mediates platelet secretion and thrombus formation through protein kinase D2Calpain-mediated regulation of platelet signaling pathways.Protein kinase C[delta] differentially regulates platelet functional responses.Differential VASP phosphorylation controls remodeling of the actin cytoskeleton.Diverse functions of protein kinase C isoforms in platelet activation and thrombus formation.Platelet physiology and antiplatelet agents.Protein kinase C-theta in platelet activation.Platelet signaling-a primer.Protein kinase C pharmacology: refining the toolbox.Secrets of platelet exocytosis - what do we really know about platelet secretion mechanisms?Platelet Rho GTPases-a focus on novel players, roles and relationships.Nobiletin, a citrus flavonoid, activates vasodilator-stimulated phosphoprotein in human platelets through non-cyclic nucleotide-related mechanisms.Coincident regulation of PKCdelta in human platelets by phosphorylation of Tyr311 and Tyr565 and phospholipase C signallingZnO Nanostructure Templates as a Cost-Efficient Mass-Producible Route for the Development of Cellular Networks.Functional divergence of platelet protein kinase C (PKC) isoforms in thrombus formation on collagen.The novel NOX inhibitor 2-acetylphenothiazine impairs collagen-dependent thrombus formation in a GPVI-dependent manner.PPARγ agonists negatively regulate αIIbβ3 integrin outside-in signaling and platelet function through up-regulation of protein kinase A activity.VASP is a CXCR2-interacting protein that regulates CXCR2-mediated polarization and chemotaxisSubmaximal inhibition of protein kinase C restores ADP-induced dense granule secretion in platelets in the presence of Ca2+.Peroxynitrite causes phosphorylation of vasodilator-stimulated phosphoprotein through a PKC dependent mechanism.Critical roles for the actin cytoskeleton and cdc42 in regulating platelet integrin alpha2beta1.Protein Kinase C as Regulator of Vascular Smooth Muscle Function and Potential Target in Vascular Disorders.Evolving Mechanisms of Vascular Smooth Muscle Contraction Highlight Key Targets in Vascular Disease.Interaction of platelets with endothelial progenitor cells in the experimental atherosclerosis: Role of transplanted endothelial progenitor cells and platelet microparticles.The Ca(2+) /calmodulin-dependent kinase kinase β-AMP-activated protein kinase-α1 pathway regulates phosphorylation of cytoskeletal targets in thrombin-stimulated human platelets.Unravelling the different functions of protein kinase C isoforms in platelets.Effect of supplementation with an 80:20cis9,trans11 conjugated linoleic acid blend on the human platelet proteome
P2860
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P2860
PKCdelta regulates collagen-induced platelet aggregation through inhibition of VASP-mediated filopodia formation
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
PKCdelta regulates collagen-in ...... P-mediated filopodia formation
@ast
PKCdelta regulates collagen-in ...... P-mediated filopodia formation
@en
PKCdelta regulates collagen-in ...... P-mediated filopodia formation
@en-gb
PKCdelta regulates collagen-in ...... P-mediated filopodia formation
@nl
type
label
PKCdelta regulates collagen-in ...... P-mediated filopodia formation
@ast
PKCdelta regulates collagen-in ...... P-mediated filopodia formation
@en
PKCdelta regulates collagen-in ...... P-mediated filopodia formation
@en-gb
PKCdelta regulates collagen-in ...... P-mediated filopodia formation
@nl
prefLabel
PKCdelta regulates collagen-in ...... P-mediated filopodia formation
@ast
PKCdelta regulates collagen-in ...... P-mediated filopodia formation
@en
PKCdelta regulates collagen-in ...... P-mediated filopodia formation
@en-gb
PKCdelta regulates collagen-in ...... P-mediated filopodia formation
@nl
P2093
P1433
P1476
PKCdelta regulates collagen-in ...... P-mediated filopodia formation
@en
P2093
Giordano Pula
Keiichi I Nakayama
Keiko Nakayama
Ulrich Walter
P304
P356
10.1182/BLOOD-2006-05-023739
P407
P577
2006-08-29T00:00:00Z