Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2
about
BRCA1 is a negative modulator of the PRC2 complexPhosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNAPRC2 during vertebrate organogenesis: a complex in transitionTargeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitorsPhosphorylation of epigenetic "readers, writers and erasers": Implications for developmental reprogramming and the epigenetic basis for health and diseaseEpigenetics and chromatin dynamics: a review and a paradigm for functional disordersLong non-coding RNA HOTAIR in carcinogenesis and metastasisA critical function of Mad2l2 in primordial germ cell development of miceRegulating repression: roles for the sir4 N-terminus in linker DNA protection and stabilization of epigenetic statesDiverse involvement of EZH2 in cancer epigeneticsThe role of EZH2 in tumour progressionJNK and STAT3 signaling pathways converge on Akt-mediated phosphorylation of EZH2 in bronchial epithelial cells induced by arsenicA polycomb group protein is retained at specific sites on chromatin in mitosisOccupying Chromatin: Polycomb Mechanisms for Getting to Genomic Targets, Stopping Transcriptional Traffic, and Staying PutThe Polycomb complex PRC2 and its mark in lifeNIPP1 maintains EZH2 phosphorylation and promoter occupancy at proliferation-related target genes.EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent.EZH2-mediated H3K27 trimethylation mediates neurodegeneration in ataxia-telangiectasia.cdc-25.4, a Caenorhabditis elegans Ortholog of cdc25, Is Required for Male Mating BehaviorEZH2: not EZHY (easy) to deal.The cyclin dependent kinase inhibitor (R)-roscovitine mediates selective suppression of alloreactive human T cells but preserves pathogen-specific and leukemia-specific effectors.Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cellsPcG complexes set the stage for epigenetic inheritance of gene silencing in early S phase before replicationRegulation and Role of EZH2 in CancerThe role of EZH2 in the regulation of the activity of matrix metalloproteinases in prostate cancer cells.Inner workings and regulatory inputs that control Polycomb repressive complex 2Pharmacologic down-regulation of EZH2 suppresses bladder cancer in vitro and in vivo.CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cellsThe roles of EZH2 in cell lineage commitment.FOXO1 inhibits Runx2 transcriptional activity and prostate cancer cell migration and invasionPolycomb protein SCML2 regulates the cell cycle by binding and modulating CDK/CYCLIN/p21 complexes.Cyclin-dependent kinase 1 (CDK1)-mediated phosphorylation of enhancer of zeste 2 (Ezh2) regulates its stability.Phosphoryl-EZH-ion.Histone modifiers in cancer: friends or foes?Targeting cell cycle regulators in hematologic malignancies.PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression.Androgens repress expression of the F-box protein Skp2 via p107 dependent and independent mechanisms in LNCaP prostate cancer cells.Tetraspanin Family Member, CD82, Regulates Expression of EZH2 via Inactivation of p38 MAPK Signaling in Leukemia Cells.Integrative genomic analyses of sporadic clear cell renal cell carcinoma define disease subtypes and potential new therapeutic targetsPLK1 and HOTAIR Accelerate Proteasomal Degradation of SUZ12 and ZNF198 during Hepatitis B Virus-Induced Liver Carcinogenesis
P2860
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P2860
Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Cyclin-dependent kinases regul ...... hrough phosphorylation of EZH2
@ast
Cyclin-dependent kinases regul ...... hrough phosphorylation of EZH2
@en
Cyclin-dependent kinases regul ...... hrough phosphorylation of EZH2
@nl
type
label
Cyclin-dependent kinases regul ...... hrough phosphorylation of EZH2
@ast
Cyclin-dependent kinases regul ...... hrough phosphorylation of EZH2
@en
Cyclin-dependent kinases regul ...... hrough phosphorylation of EZH2
@nl
prefLabel
Cyclin-dependent kinases regul ...... hrough phosphorylation of EZH2
@ast
Cyclin-dependent kinases regul ...... hrough phosphorylation of EZH2
@en
Cyclin-dependent kinases regul ...... hrough phosphorylation of EZH2
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Cyclin-dependent kinases regul ...... hrough phosphorylation of EZH2
@en
P2093
Anindya Bagchi
Aswathy N Rai
Haojie Huang
Jeffrey A Simon
Laura R Bohrer
Shuai Chen
Xianzheng Zhou
Yunqian Pan
P2860
P2888
P304
P3181
P356
10.1038/NCB2116
P407
P577
2010-11-01T00:00:00Z
P5875
P6179
1032284905