Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model
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Alpha-synuclein and tau: teammates in neurodegeneration?Generation of SNCA Cell Models Using Zinc Finger Nuclease (ZFN) Technology for Efficient High-Throughput Drug Screeningβ-amyloid triggers ALS-associated TDP-43 pathology in AD modelsMetformin lowers Ser-129 phosphorylated α-synuclein levels via mTOR-dependent protein phosphatase 2A activation.GSK-3 in Neurodegenerative Diseases.Tyrosine Kinase Inhibition Regulates Early Systemic Immune Changes and Modulates the Neuroimmune Response in α-SynucleinopathyUbiquitination increases parkin activity to promote autophagic α-synuclein clearance.Extracellular α-synuclein leads to microtubule destabilization via GSK-3β-dependent Tau phosphorylation in PC12 cellsNigral overexpression of alpha-synuclein in the absence of parkin enhances alpha-synuclein phosphorylation but does not modulate dopaminergic neurodegeneration.Parkin ubiquitinates Tar-DNA binding protein-43 (TDP-43) and promotes its cytosolic accumulation via interaction with histone deacetylase 6 (HDAC6).Decreased parkin solubility is associated with impairment of autophagy in the nigrostriatum of sporadic Parkinson's disease.Enhanced phosphatase activity attenuates α-synucleinopathy in a mouse modelDysregulation of protein phosphatase 2A in parkinson disease and dementia with lewy bodies.Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease.Heat-shock proteins in clinical neurology.Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences.Defective autophagy in Parkinson's disease: lessons from genetics.Nilotinib-induced autophagic changes increase endogenous parkin level and ubiquitination, leading to amyloid clearanceInteractions Between α-Synuclein and Tau Protein: Implications to Neurodegenerative Disorders.Wild type and P301L mutant Tau promote neuro-inflammation and α-Synuclein accumulation in lentiviral gene delivery models.Long-term overexpression of human wild-type and T240R mutant Parkin in rat substantia nigra induces progressive dopaminergic neurodegeneration.Synapses in neurodegenerative diseases.Nilotinib reverses loss of dopamine neurons and improves motor behavior via autophagic degradation of α-synuclein in Parkinson's disease models.Overexpression of parkin in the rat nigrostriatal dopamine system protects against methamphetamine neurotoxicity.
P2860
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P2860
Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model
description
2010 nî lūn-bûn
@nan
2010 թուականին հրատարակուած գիտական յօդուած
@hyw
2010 թվականին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model
@ast
Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model
@en
Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model
@en-gb
Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model
@nl
type
label
Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model
@ast
Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model
@en
Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model
@en-gb
Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model
@nl
prefLabel
Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model
@ast
Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model
@en
Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model
@en-gb
Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model
@nl
P2093
P2860
P921
P3181
P356
P1476
Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model
@en
P2093
Charbel Eh Moussa
Kathleen Maguire-Zeiss
Li Rebekah Feng
Preeti J Khandelwal
Sonya B Dumanis
P2860
P2888
P3181
P356
10.1186/1750-1326-5-47
P407
P577
2010-01-01T00:00:00Z
P5875
P6179
1027137905