Molecular cloning and functional expression of human acyl-coenzyme A:cholesterol acyltransferase cDNA in mutant Chinese hamster ovary cells
about
Localization of human acyl-coenzyme A: cholesterol acyltransferase-1 (ACAT-1) in macrophages and in various tissuesHuman acyl-coenzyme A:cholesterol acyltransferase expressed in chinese hamster ovary cells: membrane topology and active site locationRNA secondary structures located in the interchromosomal region of human ACAT1 chimeric mRNA are required to produce the 56-kDa isoformThe formation and function of ER-endosome membrane contact sitesMacrophage-mediated cholesterol handling in atherosclerosisEmerging risk biomarkers in cardiovascular diseases and disordersACAT1/SOAT1 as a therapeutic target for Alzheimer's diseaseHuman acyl-CoA:diacylglycerol acyltransferase is a tetrameric proteinIncreased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophagesMonogenic dyslipidemias: window on determinants of plasma lipoprotein metabolismEffects of prolonged ethanol intake and malnutrition on rat pancreas.Cholesterol esterification by ACAT2 is essential for efficient intestinal cholesterol absorption: evidence from thoracic lymph duct cannulationThe epigenetic drug 5-azacytidine interferes with cholesterol and lipid metabolismACAT inhibition and amyloid beta reduction.Deficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient mice.Polymorphism of rs1044925 in the acyl-CoA:cholesterol acyltransferase-1 gene and serum lipid levels in the Guangxi Bai Ku Yao and Han populations.Microsomal triglyceride transfer protein enhances cellular cholesteryl esterification by relieving product inhibition.Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis.Rat carboxylesterase ES-4 enzyme functions as a major hepatic neutral cholesteryl ester hydrolase.Acyl-coenzyme A:cholesterol acyltransferase 1 blockage enhances autophagy in the neurons of triple transgenic Alzheimer's disease mouse and reduces human P301L-tau content at the presymptomatic stage.Sex-specific association of ACAT-1 rs1044925 SNP and serum lipid levels in the hypercholesterolemic subjectsNormalization of cholesterol homeostasis by 2-hydroxypropyl-β-cyclodextrin in neurons and glia from Niemann-Pick C1 (NPC1)-deficient miceModulation of endosomal cholesteryl ester metabolism by membrane cholesterol.Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: evidence suggesting multiple cholesterol esterification enzymes in mammals.ACAT1 regulates the dynamics of free cholesterols in plasma membrane which leads to the APP-α-processing alteration.Myeloid Acyl-CoA:Cholesterol Acyltransferase 1 Deficiency Reduces Lesion Macrophage Content and Suppresses Atherosclerosis ProgressionTransport of LDL-derived cholesterol from the NPC1 compartment to the ER involves the trans-Golgi network and the SNARE protein complexProduction of ACAT1 56-kDa isoform in human cells via trans-splicing involving the ampicillin resistance gene.Beyond triglyceride synthesis: the dynamic functional roles of MGAT and DGAT enzymes in energy metabolismMassive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1.The lipid-laden foam cell: an elusive target for therapeutic intervention.Intestinal lipid absorption.The genetics of neutral lipid biosynthesis: an evolutionary perspectiveAcyl-coenzyme A:cholesterol acyltransferases.Association between single nucleotide polymorphism rs1044925 and the risk of coronary artery disease and ischemic stroke.Sterols and sphingolipids: dynamic duo or partners in crime?Acyl-CoA:cholesterol acyltransferases (ACATs/SOATs): Enzymes with multiple sterols as substrates and as activators.Low-level expression of human ACAT2 gene in monocytic cells is regulated by the C/EBP transcription factors.The ACAT2 expression of human leukocytes is responsible for the excretion of lipoproteins containing cholesteryl/steryl esters.Cellular Cholesterol Homeostasis in Alzheimer's Disease.
P2860
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P2860
Molecular cloning and functional expression of human acyl-coenzyme A:cholesterol acyltransferase cDNA in mutant Chinese hamster ovary cells
description
1993 nî lūn-bûn
@nan
1993 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Molecular cloning and function ...... nt Chinese hamster ovary cells
@ast
Molecular cloning and function ...... nt Chinese hamster ovary cells
@en
Molecular cloning and function ...... nt Chinese hamster ovary cells
@en-gb
Molecular cloning and function ...... nt Chinese hamster ovary cells
@nl
type
label
Molecular cloning and function ...... nt Chinese hamster ovary cells
@ast
Molecular cloning and function ...... nt Chinese hamster ovary cells
@en
Molecular cloning and function ...... nt Chinese hamster ovary cells
@en-gb
Molecular cloning and function ...... nt Chinese hamster ovary cells
@nl
prefLabel
Molecular cloning and function ...... nt Chinese hamster ovary cells
@ast
Molecular cloning and function ...... nt Chinese hamster ovary cells
@en
Molecular cloning and function ...... nt Chinese hamster ovary cells
@en-gb
Molecular cloning and function ...... nt Chinese hamster ovary cells
@nl
P2093
P1476
Molecular cloning and function ...... nt Chinese hamster ovary cells
@en
P2093
P304
20747-20755
P407
P577
1993-10-01T00:00:00Z