Structure of the TRPA1 ion channel suggests regulatory mechanisms
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TRPV1: A Target for Rational Drug DesignTRP channels in schistosomesCryo-EM studies of the structure and dynamics of vacuolar-type ATPasesTRP channels: a missing bond in the entrainment mechanism of peripheral clocks throughout evolutionDevelopment of the field of structural physiologyMembrane protein structures without crystals, by single particle electron cryomicroscopyHow the TRPA1 receptor transmits painful stimuli: Inner workings revealed by electron cryomicroscopyTwo-Dimensional Crystallization Procedure, from Protein Expression to Sample PreparationEvidence for Novel Pharmacological Sensitivities of Transient Receptor Potential (TRP) Channels in Schistosoma mansoniA saposin-lipoprotein nanoparticle system for membrane proteins.Structure of the full-length TRPV2 channel by cryo-EM.Ankyrin Repeats Convey Force to Gate the NOMPC Mechanotransduction ChannelArchitecture of the mammalian mechanosensitive Piezo1 channelStructure of the voltage-gated calcium channel Cav1.1 complexTransient receptor potential canonical 4 and 5 proteins as targets in cancer therapeuticsStructure, inhibition and regulation of two-pore channel TPC1 from Arabidopsis thalianaMaltose-Binding Protein (MBP), a Secretion-Enhancing Tag for Mammalian Protein Expression SystemsCrystal structure of the epithelial calcium channel TRPV6Structural basis of TRPA1 inhibition by HC-030031 utilizing species-specific differences.N-terminal tetrapeptide T/SPLH motifs contribute to multimodal activation of human TRPA1 channelIsoform-specific modulation of the chemical sensitivity of conserved TRPA1 channel in the major honeybee ectoparasitic mite, Tropilaelaps mercedesaeImplications of Human Transient Receptor Potential Melastatin 8 (TRPM8) Channel Gating from Menthol Binding Studies of the Sensing DomainMolecular insights into lipid-assisted Ca(2+) regulation of the TRP channel Polycystin-2Single-particle electron microscopy in the study of membrane protein structureThe changing landscape of membrane protein structural biology through developments in electron microscopy.Asynchronous data acquisition and on-the-fly analysis of dose fractionated cryoEM images by UCSFImage.The First Extracellular Linker Is Important for Several Aspects of the Gating Mechanism of Human TRPA1 Channel.Primidone inhibits TRPM3 and attenuates thermal nociception in vivoCharacterization of TRPA channels in the starfish Patiria pectinifera: involvement of thermally activated TRPA1 in thermotaxis in marine planktonic larvaeMethods to account for movement and flexibility in cryo-EM data processing.TRPA1 Channels Modify TRPV1-Mediated Current Responses in Dorsal Root Ganglion Neurons.TRPA1 expression and its functional activation in rodent cortex.The S1 helix critically regulates the finely tuned gating of Kv11.1 channelsTRPV1 temperature activation is specifically sensitive to strong decreases in amino acid hydrophobicity.A-Kinase Anchoring Protein 79/150 Scaffolds Transient Receptor Potential A 1 Phosphorylation and Sensitization by Metabotropic Glutamate Receptor Activation.Thermogenetic neurostimulation with single-cell resolution.Accessible Mannitol-Based Amphiphiles (MNAs) for Membrane Protein Solubilisation and StabilisationInflammatory pain control by blocking oxidized phospholipid-mediated TRP channel activation.Comparative sequence analysis suggests a conserved gating mechanism for TRP channels.Modeling Suggests TRPC3 Hydrogen Bonding and Not Phosphorylation Contributes to the Ataxia Phenotype of the Moonwalker Mouse.
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P2860
Structure of the TRPA1 ion channel suggests regulatory mechanisms
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2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2015 թվականի ապրիլին հրատարակված գիտական հոդված
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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Structure of the TRPA1 ion channel suggests regulatory mechanisms
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Structure of the TRPA1 ion channel suggests regulatory mechanisms
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Structure of the TRPA1 ion channel suggests regulatory mechanisms
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Structure of the TRPA1 ion channel suggests regulatory mechanisms
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Structure of the TRPA1 ion channel suggests regulatory mechanisms
@ast
Structure of the TRPA1 ion channel suggests regulatory mechanisms
@en
Structure of the TRPA1 ion channel suggests regulatory mechanisms
@en-gb
Structure of the TRPA1 ion channel suggests regulatory mechanisms
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Structure of the TRPA1 ion channel suggests regulatory mechanisms
@ast
Structure of the TRPA1 ion channel suggests regulatory mechanisms
@en
Structure of the TRPA1 ion channel suggests regulatory mechanisms
@en-gb
Structure of the TRPA1 ion channel suggests regulatory mechanisms
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Structure of the TRPA1 ion channel suggests regulatory mechanisms
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Candice E Paulsen
David Julius
Yifan Cheng
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P356
10.1038/NATURE14367
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P577
2015-04-08T00:00:00Z
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1001554254