Taxol biosynthesis: taxane 13 alpha-hydroxylase is a cytochrome P450-dependent monooxygenase - Wikidata - wikimedia - TriplyDB

Taxol biosynthesis: taxane 13 alpha-hydroxylase is a cytochrome P450-dependent monooxygenase

Taxol biosynthesis: taxane 13 alpha-hydroxylase is a cytochrome P450-dependent monooxygenase

http://www.wikidata.org/entity/Q24555092

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Kinetic and molecular analysis of 5-epiaristolochene 1,3-dihydroxylase, a cytochrome P450 enzyme catalyzing successive hydroxylations of sesquiterpenes CYP76M7 is an ent-cassadiene C11alpha-hydroxylase defining a second multifunctional diterpenoid biosynthetic gene cluster in rice Licorice beta-amyrin 11-oxidase, a cytochrome P450 with a key role in the biosynthesis of the triterpene sweetener glycyrrhizin Studies on Taxol biosynthesis: preparation of taxadiene-diol and triol derivatives by deoxygenation of taxusin Recent advances in biosynthesis of bioactive compounds in traditional Chinese medicinal plants Molecular Approaches to Screen Bioactive Compounds from Endophytic Fungi Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation Cytochrome P450 oxygenases of Taxol biosynthesis.Random sequencing of an induced Taxus cell cDNA library for identification of clones involved in Taxol biosynthesis Cytochrome P450 enzymes in the generation of commercial products.The final acylation step in taxol biosynthesis: cloning of the taxoid C13-side-chain N-benzoyltransferase from Taxus.Taxol biosynthesis and molecular genetics Studies on Taxol® Biosynthesis. Preparation and Tritium Labeling of Biosynthetic intermediates by Deoxygenation of a Taxadiene Tetra-acetate Obtained from Japanese Yew.A retrosynthetic biology approach to metabolic pathway design for therapeutic production Natural products version 2.0: connecting genes to molecules.Identification and expression analysis of methyl jasmonate responsive ESTs in paclitaxel producing Taxus cuspidata suspension culture cells Natural products synthesis: enabling tools to penetrate Nature's secrets of biogenesis and biomechanism.An approach to the site-selective deoxygenation of hydroxy groups based on catalytic phosphoramidite transfer Administering cultured Taxus cells with early precursors reveals bifurcations in the taxoid biosynthetic pathway.The early stages of taxol biosynthesis: an interim report on the synthesis and identification of early pathway metabolites.Genes, enzymes and chemicals of terpenoid diversity in the constitutive and induced defence of conifers against insects and pathogens.Anticancer drugs from nature--natural products as a unique source of new microtubule-stabilizing agents.Constructing de novo biosynthetic pathways for chemical synthesis inside living cells.Taxol biosynthesis: Identification and characterization of two acetyl CoA:taxoid-O-acetyl transferases that divert pathway flux away from Taxol production.The Arabidopsis cytochrome P450 CYP707A encodes ABA 8'-hydroxylases: key enzymes in ABA catabolism.Microbial paclitaxel: advances and perspectives.Current approaches toward production of secondary plant metabolites.Downstream reactions and engineering in the microbially reconstituted pathway for Taxol.Endophytic fungi: novel sources of anticancer lead molecules.Research progress relating to the role of cytochrome P450 in the biosynthesis of terpenoids in medicinal plants.Correlation analysis of the taxane core functional group modification, enzyme expression, and metabolite accumulation profiles under methyl jasmonate treatment.A Cytochrome P450 3A4 Biosensor Based on Generation 4.0 PAMAM Dendrimers for the Detection of Caffeine.Analysis of heterologous taxadiene production in K- and B-derived Escherichia coli.Transcriptome Assembly and Systematic Identification of Novel Cytochrome P450s in Taxus chinensis.Triterpene functional genomics in licorice for identification of CYP72A154 involved in the biosynthesis of glycyrrhizin.Association genetics of oleoresin flow in loblolly pine: discovering genes and predicting phenotype for improved resistance to bark beetles and bioenergy potential.Arabidopsis CYP707As encode (+)-abscisic acid 8'-hydroxylase, a key enzyme in the oxidative catabolism of abscisic acid.Production of isoprenoid pharmaceuticals by engineered microbes.Comparative proteomic analyses of two Taxus species (Taxus × media and Taxus mairei) reveals variations in the metabolisms associated with paclitaxel and other metabolites.Identification of potential genes that contributed to the variation in the taxoid contents between two Taxus species (Taxus media and Taxus mairei).

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Taxol biosynthesis: taxane 13 alpha-hydroxylase is a cytochrome P450-dependent monooxygenase

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2001 nî lūn-bûn

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2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2001 թվականի նոյեմբերին հրատարակված գիտական հոդված

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Taxol biosynthesis: taxane 13 ...... e P450-dependent monooxygenase

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Taxol biosynthesis: taxane 13 ...... e P450-dependent monooxygenase

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Taxol biosynthesis: taxane 13 ...... e P450-dependent monooxygenase

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Taxol biosynthesis: taxane 13 ...... e P450-dependent monooxygenase

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Taxol biosynthesis: taxane 13 ...... e P450-dependent monooxygenase

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Taxol biosynthesis: taxane 13 ...... e P450-dependent monooxygenase

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Taxol biosynthesis: taxane 13 ...... e P450-dependent monooxygenase

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Taxol biosynthesis: taxane 13 ...... e P450-dependent monooxygenase

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Taxol biosynthesis: taxane 13 ...... e P450-dependent monooxygenase

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Proceedings of the National Academy of Sciences of the United States of America

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Taxol biosynthesis: taxane 13 ...... e P450-dependent monooxygenase

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C D Rithner

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R B Croteau

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R M Williams

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S Jennewein

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P2860

Taxol biosynthesis: molecular cloning of a benzoyl-CoA:taxane 2alpha-O-benzoyltransferase cDNA from taxus and functional expression in Escherichia coli

Molecular cloning of a 10-deacetylbaccatin III-10-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Taxol biosynthesis: differential transformations of taxadien-5 alpha-ol and its acetate ester by cytochrome P450 hydroxylases from Taxus suspension cells

Total synthesis of taxol

Cytochrome P450-catalyzed hydroxylation of taxa-4(5),11(12)-diene to taxa-4(20),11(12)-dien-5alpha-ol: the first oxygenation step in taxol biosynthesis

Cyclization of geranylgeranyl diphosphate to taxa-4(5),11(12)-diene is the committed step of taxol biosynthesis in Pacific yew

Enantioselective Total Synthesis of Taxol

THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. II. SOLUBILIZATION, PURIFICATION, AND PROPERTIES

Molecular cloning of a taxa-4(20),11(12)-dien-5alpha-ol-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli.

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13595-600

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2571277

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10.1073/PNAS.251539398

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24

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98

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11707604

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61086

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