Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein
about
WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodiesTim50a, a nuclear isoform of the mitochondrial Tim50, interacts with proteins involved in snRNP biogenesis.A novel EB-1/AIDA-1 isoform, AIDA-1c, interacts with the Cajal body protein coilin.Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel componentIdentification and characterization of Gemin7, a novel component of the survival of motor neuron complexCoilin interacts with Ku proteins and inhibits in vitro non-homologous DNA end joiningCharacterization of hCINAP, a novel coilin-interacting protein encoded by a transcript from the transcription factor TAFIID32 locusOngoing U snRNP biogenesis is required for the integrity of Cajal bodiesGemin proteins are required for efficient assembly of Sm-class ribonucleoproteins.The Cajal body and histone locus bodyThe cyclin E/Cdk2 substrate p220(NPAT) is required for S-phase entry, histone gene expression, and Cajal body maintenance in human somatic cellsCajal-body formation correlates with differential coilin phosphorylation in primary and transformed cell linesCajal bodies and coilin--moving towards functionSMN, the spinal muscular atrophy protein, forms a pre-import snRNP complex with snurportin1 and importin betaDephosphorylation of survival motor neurons (SMN) by PPM1G/PP2Cgamma governs Cajal body localization and stability of the SMN complexELL and EAF1 are Cajal body components that are disrupted in MLL-ELL leukemiaCoilin: The first 25 yearsDeterminants of the interaction of the spinal muscular atrophy disease protein SMN with the dimethylarginine-modified box H/ACA small nucleolar ribonucleoprotein GAR1UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic developmentSMN in spinal muscular atrophy and snRNP biogenesisMolecular determinants of survival motor neuron (SMN) protein cleavage by the calcium-activated protease, calpainCoilin phosphomutants disrupt Cajal body formation, reduce cell proliferation and produce a distinct coilin degradation product.Symmetrical dimethylarginine methylation is required for the localization of SMN in Cajal bodies and pre-mRNA splicing.Reduced viability, fertility and fecundity in mice lacking the cajal body marker protein, coilin.Genetic analysis of nuclear bodies: from nondeterministic chaos to deterministic order.Coilin participates in the suppression of RNA polymerase I in response to cisplatin-induced DNA damage.The role of nuclear bodies in gene expression and disease.The product of the survival of motor neuron (SMN) gene is a human telomerase-associated protein.Sequence-specific interaction of U1 snRNA with the SMN complexIn vitro RNase and nucleic acid binding activities implicate coilin in U snRNA processingThe SMN complex is associated with snRNPs throughout their cytoplasmic assembly pathwayDynamic nature of cleavage bodies and their spatial relationship to DDX1 bodies, Cajal bodies, and gems.The C-terminal domain of coilin interacts with Sm proteins and U snRNPs.Tudor domains bind symmetrical dimethylated arginines.Plant coilin: structural characteristics and RNA-binding properties.Repair of pre-mRNA splicing: prospects for a therapy for spinal muscular atrophy.Modification of Sm small nuclear RNAs occurs in the nucleoplasmic Cajal body following import from the cytoplasmRegulation of neuronal differentiation by proteins associated with nuclear bodies.ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP.In vivo kinetics of Cajal body components
P2860
Q21145787-328A0ADE-EAB2-4F34-8F1E-1784EFF354E4Q21284169-F953674D-4FE0-4233-A2BF-35589ADAD29AQ21284170-F4254F7F-0C94-42DF-A24F-1C98EAE62210Q24292040-6B4D2AD4-A89E-492A-9E4B-DCD6FC988690Q24299793-3FBE139F-BBB3-430B-BA24-7CEEF29D50AAQ24306712-43C2E46D-46FC-45D5-AD45-F006CA16AA7BQ24312861-164EDCEE-35F5-4183-9E48-71C56441B253Q24336921-1851D1DB-428F-4892-A0C7-C04B1A62F9F0Q24536283-50CFCD1E-8BCD-4C58-B1AD-DA04EED591AAQ24630829-24F08E03-D7F7-4C13-9D5B-032FFFF37DEFQ24648864-A91BAA56-4768-453B-A968-D332C8190BCBQ24658020-933B268D-4DB9-49A2-986D-7699115809F1Q24672790-7565EF41-E480-4C48-822A-B9F54EB1EC2CQ24676334-4C05DA3A-91C3-400D-B50A-23AD03F4615FQ24682443-E15C1D59-C3E1-43BD-BD2F-2C69C4733494Q24683043-9F6D235B-3D31-4654-AF51-69A4054A6A47Q28084574-CDA2A99C-2046-4900-B8ED-8C19C33B83DCQ28203025-6092B156-2945-4515-B225-30E10242CAA1Q28484095-55EDDCF1-EE29-4F1D-8723-4121DAD81A80Q29013847-5F961CA8-1EC7-4652-8E98-93AC3D790C1CQ30994078-011F637B-B74B-42B8-A601-3AC749BA64FCQ31032498-A998DDC3-93C7-49DC-B21C-5488DB4D1210Q31121644-C7FD9804-E5DB-4E86-9846-D1D9D37AA555Q33480004-7300823F-71B6-49E7-A74C-39EC785CBB2CQ33775603-C022FBF7-3461-4438-AB85-6E89FDF8F506Q33810822-EAFD0B1B-31CC-4FCA-8F97-0F63E2A48556Q34038183-A3763820-F7B8-40BD-A93A-0B91E8056F9AQ34060945-C11524A8-6F70-4DAC-9E08-80F840E87017Q34086103-02C59855-B5BE-41A0-AFAD-841C6862461CQ34257423-3DB2C33D-FC95-4FF7-AA88-6067EF0A012CQ34324754-FD759BA2-B25E-4F33-8691-5632A14388A1Q34407246-BDF04674-8514-4F5B-86D3-8678B76A22CEQ34425050-F5F653C1-F7A9-4F78-ADBE-575066E0C6C7Q34426427-C3EFA528-5049-4599-86C8-42AB412FE5E8Q34548288-678B4670-4159-4955-B2B4-1F1FD89DEC2BQ34762623-36EB5571-1B66-4A50-8A70-C756DD4F32C9Q34985924-418E1D69-9776-48D4-8770-0703D096A8CAQ35072924-39017EFD-B7A1-4594-9BDB-01A311EF777BQ35114564-AAF7FE77-B941-4047-A37B-BF6C4E1E92A5Q35121375-FD12BDF4-EDC2-40CE-80B3-9562E0E681F0
P2860
Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein
@ast
Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein
@en
Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein
@nl
type
label
Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein
@ast
Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein
@en
Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein
@nl
prefLabel
Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein
@ast
Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein
@en
Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein
@nl
P2093
P2860
P3181
P356
P1433
P1476
Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein
@en
P2093
K B Shpargel
M D Hebert
P W Szymczyk
P2860
P304
P3181
P356
10.1101/GAD.908401
P407
P577
2001-10-01T00:00:00Z