about
Heat shock protein-90-alpha, a prolactin-STAT5 target gene identified in breast cancer cells, is involved in apoptosis regulationInteraction of Hsp90 with ribosomal proteins protects from ubiquitination and proteasome-dependent degradationSystematic Analysis Reveals Elongation Factor 2 and α-Enolase as Novel Interaction Partners of AKT2Regulation of AKT phosphorylation at Ser473 and Thr308 by endoplasmic reticulum stress modulates substrate specificity in a severity dependent mannerSuppression of the mTOR-raptor signaling pathway by the inhibitor of heat shock protein 90 geldanamycinHsp60 regulation of tumor cell apoptosisAkt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 functionS-nitrosylation of Hsp90 promotes the inhibition of its ATPase and endothelial nitric oxide synthase regulatory activitiesIntegrin alphavbeta3, requirement for VEGFR2-mediated activation of SAPK2/p38 and for Hsp90-dependent phosphorylation of focal adhesion kinase in endothelial cells activated by VEGFHeat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha.3-Phosphoinositide-dependent protein kinase-1-mediated IkappaB kinase beta (IkkB) phosphorylation activates NF-kappaB signalingEmerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer developmentHuman host factors required for influenza virus replicationTherapeutic Implications of Targeting AKT Signaling in MelanomaA comprehensive pathway map of epidermal growth factor receptor signalingTranslational Research to Improve the Efficacy of Carbon Ion Radiotherapy: Experience of Gunma UniversityParalog Specific Hsp90 Inhibitors - A Brief History and a Bright FutureEvolving concepts in cancer therapy through targeting sphingolipid metabolismRegulation of mTORC1 by PI3K signalingTargeting Hsp90 in urothelial carcinomaFunctions of the Hsp90 chaperone system: lifting client proteins to new heightsThe hexameric structures of human heat shock protein 90Cochaperone Activity of Human Butyrate-Induced Transcript 1 Facilitates Hepatitis C Virus Replication through an Hsp90-Dependent PathwayUDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib.The critical role of Akt in cardiovascular functionCAIR-1/BAG-3 abrogates heat shock protein-70 chaperone complex-mediated protein degradation: accumulation of poly-ubiquitinated Hsp90 client proteinsMolecular identification of Aggrus/T1alpha as a platelet aggregation-inducing factor expressed in colorectal tumorsRegulation of telomerase activity and anti-apoptotic function by protein-protein interaction and phosphorylationRegulation of kinase activity of 3-phosphoinositide-dependent protein kinase-1 by binding to 14-3-3ArgBP2gamma interacts with Akt and p21-activated kinase-1 and promotes cell survivalPIKE (phosphatidylinositol 3-kinase enhancer)-A GTPase stimulates Akt activity and mediates cellular invasionInTERTesting association between telomerase, mTOR and phytochemicalsPhase I trial of 17-dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG), a heat shock protein inhibitor, administered twice weekly in patients with advanced malignanciesNF-kappaB and the immune responseA proteomic snapshot of the human heat shock protein 90 interactomeDownregulation of caveolin-1 enhances fusion of human BeWo choriocarcinoma cellsHeat shock protein 90 positively regulates Chikungunya virus replication by stabilizing viral non-structural protein nsP2 during infectionOxidative Stress Mediates the Antiproliferative Effects of Nelfinavir in Breast Cancer CellsProtein kinase C-delta mediates neuronal apoptosis in the retinas of diabetic rats via the Akt signaling pathwayDifferential hypoxic tolerance is mediated by activation of heat shock response and nitric oxide pathway
P2860
Q21195216-486FA28C-4A57-42F1-95C0-DB08C5CC9222Q24297095-001B4C13-BBCD-4CE5-A81B-DE3B4E171C99Q24297375-C9B230C5-3E0A-4C33-AA5D-11EFAC83DC5DQ24298269-AA56B3FE-9DF4-4D03-BAC8-3FFC4E22692EQ24301667-7C60C6F9-0CD8-44F7-97D7-9A4FBE3B8658Q24303954-AB20C13E-D1F0-4C06-A343-5E23D3118B7AQ24304442-DEF355F1-D166-4A7E-BD69-2F6EC0964725Q24304473-4E5F47EB-3261-427B-858A-DFFFEE2DCC0BQ24306175-03EADAC8-40C2-4ABF-B714-4D2CB3BCB93BQ24320638-50D3746A-BDF7-4E86-B916-051FC35C9EFDQ24337691-82846FE6-4D56-4DB4-AFAE-E26C83D9FDA4Q24622802-7AA0AB0F-8A83-4947-906D-B596F815B8ECQ24629972-E2A1AD08-D5A3-43CD-9418-AEA744406F8CQ24631438-66B04542-4502-403D-9FB2-03A232117BC4Q24672490-5E2A6E6B-3D0C-41A5-91B5-341D01BD25D3Q26744799-00FDD179-8C43-4122-95E6-1C3EECD35761Q26748800-69370E50-55C6-4EC8-A0E7-DABE978BFE45Q26863646-FAF77A63-1774-4309-96B5-94D3EAC2DFBAQ26995791-60457A8F-0B88-4390-ABFC-D4C2D1A8DCC3Q27023406-C852754A-F1F5-43C9-ACFA-8EC40C95B485Q27024085-A5A48986-8A5C-4878-9D8D-5499E4327DE2Q27340111-475C23B9-CC02-435C-91C8-E6DFCE598D6AQ27489790-AB6CA169-60C5-41CF-9938-D6023CC20BE2Q27853065-6A7C05F3-0C8D-4D18-A824-4640EF0C65E7Q28083829-2483C113-C7DB-4734-9B15-58DA06996C7AQ28204432-92F644F3-5A3C-4BC5-A53F-B9D3A42D730AQ28206434-17FD4B5D-01D5-4A34-B424-55B1C8322904Q28209368-092E2BAD-8077-435E-8460-FE950F39A0FCQ28217875-A8DF77BE-1CEB-4A70-8587-D2FCBB272578Q28241283-E97C9387-7CA6-4B4C-9A8B-783630D5045AQ28242382-AF6F96DB-F7D9-4612-8D56-8F4AF839CFF8Q28262993-ADFB6DF1-8819-4A12-91FB-DF0DB36F6620Q28266067-33514A38-67CC-4C54-B123-CEE54A0100EEQ28271031-D0D94138-5EB2-494D-98F3-915489DDECAEQ28279879-180CC063-C784-403F-9312-933871FFEE69Q28473861-77DF1866-3D5C-4B5E-9644-1555F9CC55F2Q28539964-FE21B858-D4CF-4A48-A42E-DADB44F528F4Q28550200-AE0B1ACA-7C0C-4972-B644-A778F394B171Q28572961-7339D3AC-32D2-4D31-AE61-B3FBFA6ED57BQ28579578-C5155A6B-B291-4471-B9EB-A3B88DC6B1E7
P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Modulation of Akt kinase activity by binding to Hsp90
@ast
Modulation of Akt kinase activity by binding to Hsp90
@en
Modulation of Akt kinase activity by binding to Hsp90
@nl
type
label
Modulation of Akt kinase activity by binding to Hsp90
@ast
Modulation of Akt kinase activity by binding to Hsp90
@en
Modulation of Akt kinase activity by binding to Hsp90
@nl
prefLabel
Modulation of Akt kinase activity by binding to Hsp90
@ast
Modulation of Akt kinase activity by binding to Hsp90
@en
Modulation of Akt kinase activity by binding to Hsp90
@nl
P2093
P2860
P3181
P356
P1476
Modulation of Akt kinase activity by binding to Hsp90
@en
P2093
P2860
P304
P3181
P356
10.1073/PNAS.170276797
P407
P577
2000-09-26T00:00:00Z