Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7
about
Structural basis for the Zn2+ inhibition of the zymogen-like kallikrein-related peptidase 10Involvement of corneodesmosome degradation and lamellar granule transportation in the desquamation processSpontaneous proton transfer to a conserved intein residue determines on-pathway protein splicing.Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity.Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics.The discovery of compounds that stimulate the activity of kallikrein-related peptidase 3 (KLK3).Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs).The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10.Kallikreins - The melting pot of activity and functionReflections on the tissue kallikrein and kallikrein-related peptidase family - from mice to men - what have we learnt in the last two decades?Order and disorder in corneocyte adhesion.Stratum corneum proteases and dry skin conditions.The biology and regulation of corneodesmosomes.Unleashing the therapeutic potential of human kallikrein-related serine proteases.Correlation of the expression of human kallikrein-related peptidases 4 and 7 with the prognosis in oral squamous cell carcinoma.Mass spectrometry-based determination of Kallikrein-related peptidase 7 (KLK7) cleavage preferences and subsite dependency.Kallikrein-related peptidases (KLKs) as emerging therapeutic targets: focus on prostate cancer and skin pathologies.Novel Biological Substrates of Human Kallikrein 7 Identified through Degradomics.Inhibitors of kallikrein-related peptidases: An overview.Network approach for capturing ligand-induced subtle global changes in protein structures.Loss of kallikrein-related peptidase 7 exacerbates amyloid pathology in Alzheimer's disease model mice.Mass spectrometry based proteomics analyses in kallikrein-related peptidase research: implications for cancer research and therapy.Kallikrein-related peptidase 7 is a potential target for the treatment of pancreatic cancer.Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1
P2860
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P2860
Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
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2007年論文
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2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
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name
Chymotryptic specificity deter ...... ited human tissue kallikrein 7
@ast
Chymotryptic specificity deter ...... ited human tissue kallikrein 7
@en
Chymotryptic specificity deter ...... ited human tissue kallikrein 7
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type
label
Chymotryptic specificity deter ...... ited human tissue kallikrein 7
@ast
Chymotryptic specificity deter ...... ited human tissue kallikrein 7
@en
Chymotryptic specificity deter ...... ited human tissue kallikrein 7
@nl
prefLabel
Chymotryptic specificity deter ...... ited human tissue kallikrein 7
@ast
Chymotryptic specificity deter ...... ited human tissue kallikrein 7
@en
Chymotryptic specificity deter ...... ited human tissue kallikrein 7
@nl
P2093
P2860
P3181
P356
P1476
Chymotryptic specificity deter ...... ited human tissue kallikrein 7
@en
P2093
Mekdes Debela
Norman M Schechter
Petra Hess
Robert Huber
Thomas Steiner
Viktor Magdolen
P2860
P304
P3181
P356
10.1073/PNAS.0707811104
P407
P577
2007-10-09T00:00:00Z