Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity
about
Bcl-x(L) sequesters its C-terminal membrane anchor in soluble, cytosolic homodimersEvidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic functionProapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.Ankyrin repeat and suppressors of cytokine signaling box protein asb-9 targets creatine kinase B for degradationAn internal EELD domain facilitates mitochondrial targeting of Mcl-1 via a Tom70-dependent pathwayStructural Basis for Apoptosis Inhibition by Epstein-Barr Virus BHRF1The restricted binding repertoire of Bcl-B leaves Bim as the universal BH3-only prosurvival Bcl-2 protein antagonistA1/Bfl-1 in leukocyte development and cell deathIntegral membrane proteins in the mitochondrial outer membrane of Saccharomyces cerevisiae.Building blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosisFNDC3A is required for adhesion between spermatids and Sertoli cellsBcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell lineIntrinsically disordered proteins in bcl-2 regulated apoptosis.An imbalance between apoptosis and proliferation contributes to follicular persistence in polycystic ovaries in ratsAuto-activation of the apoptosis protein Bax increases mitochondrial membrane permeability and is inhibited by Bcl-2A novel Bcl-2-like inhibitor of apoptosis is encoded by the parapoxvirus ORF virusBcl-XL inhibits membrane permeabilization by competing with Bax.Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundanceROS production is essential for the apoptotic function of E2F1 in pheochromocytoma and neuroblastoma cell lines.The Bcl-2 family: roles in cell survival and oncogenesis.Ligand binding and membrane insertion compete with oligomerization of the BclXL apoptotic repressorBcl-w protects hippocampus during experimental status epilepticus.Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak.BCL2 family of apoptosis-related genes: functions and clinical implications in cancer.Exploring the contribution of estrogen to amyloid-Beta regulation: a novel multifactorial computational modeling approach.Direct activation of full-length proapoptotic BAKChelerythrine induces apoptosis through a Bax/Bak-independent mitochondrial mechanism.Embedded together: the life and death consequences of interaction of the Bcl-2 family with membranes.Yeast techniques for modeling drugs targeting Bcl-2 and caspase family members.Mechanisms of action of Bcl-2 family proteinsBlood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8alpha+ dendritic cells.Bim regulation may determine hippocampal vulnerability after injurious seizures and in temporal lobe epilepsy.C-terminal residues regulate localization and function of the antiapoptotic protein Bfl-1.Molecular basis for Bcl-2 homology 3 domain recognition in the Bcl-2 protein family: identification of conserved hot spot interactions.Structural biology of the intrinsic cell death pathway: what do we know and what is missing?In vivo contributions of BH3-only proteins to neuronal death following seizures, ischemia, and traumatic brain injury.How vaccinia virus has evolved to subvert the host immune response.The Bcl-2 family: structures, interactions and targets for drug discovery.The use of a neutral peptide aptamer scaffold to anchor BH3 peptides constitutes a viable approach to studying their functionBAX to basics: How the BCL2 gene family controls the death of retinal ganglion cells.
P2860
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P2860
Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Proapoptotic BH3-only proteins ...... -w and neutralize its activity
@ast
Proapoptotic BH3-only proteins ...... -w and neutralize its activity
@en
Proapoptotic BH3-only proteins ...... -w and neutralize its activity
@nl
type
label
Proapoptotic BH3-only proteins ...... -w and neutralize its activity
@ast
Proapoptotic BH3-only proteins ...... -w and neutralize its activity
@en
Proapoptotic BH3-only proteins ...... -w and neutralize its activity
@nl
prefLabel
Proapoptotic BH3-only proteins ...... -w and neutralize its activity
@ast
Proapoptotic BH3-only proteins ...... -w and neutralize its activity
@en
Proapoptotic BH3-only proteins ...... -w and neutralize its activity
@nl
P2093
P2860
P356
P1476
Proapoptotic BH3-only proteins ...... -w and neutralize its activity
@en
P2093
David C S Huang
George Hausmann
Jennifer G Beaumont
Jerry M Adams
Julie Wilson-Annan
Loes P Parma
Lorraine A O'Reilly
Mark G Hinds
Martin Lackmann
P2860
P304
P356
10.1083/JCB.200302144
P407
P577
2003-09-01T00:00:00Z