Inhibition of microglia activation as a phenotypic assay in early drug discovery
about
Label-free imaging to study phenotypic behavioural traits of cells in complex co-cultures.High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma CellsFunctional characterization of a competitive peptide antagonist of p65 in human macrophage-like cells suggests therapeutic potential for chronic inflammation.Small molecule glutaminase inhibitors block glutamate release from stimulated microglia.Methamphetamine alters microglial immune function through P2X7R signaling.The Use of Antibodies in Small-Molecule Drug Discovery.Maternal immune activation and abnormal brain development across CNS disorders.Main path and byways: non-vesicular glutamate release by system xc(-) as an important modifier of glutamatergic neurotransmission.HuR promotes the molecular signature and phenotype of activated microglia: Implications for amyotrophic lateral sclerosis and other neurodegenerative diseases.Glial cells as drug targets: What does it take?Inflammation, Glutamate, and Glia: A Trio of Trouble in Mood Disorders.Development of a primary microglia screening assay and its use to characterize inhibition of system xc- by erastin and its analogs.Plant polyphenols as inhibitors of NF-κB induced cytokine production-a potential anti-inflammatory treatment for Alzheimer's disease?Anti-Neuroinflammatory Effect of MC13, a Novel Coumarin Compound From Condiment Murraya, Through Inhibiting Lipopolysaccharide-Induced TRAF6-TAK1-NF-κB, P38/ERK MAPKS and Jak2-Stat1/Stat3 Pathways.The human microglial HMC3 cell line: where do we stand? A systematic literature reviewEffect of Chlorogenic Acid Supplementation in MPTP-Intoxicated Mouse
P2860
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P2860
Inhibition of microglia activation as a phenotypic assay in early drug discovery
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Inhibition of microglia activation as a phenotypic assay in early drug discovery
@ast
Inhibition of microglia activation as a phenotypic assay in early drug discovery
@en
Inhibition of microglia activation as a phenotypic assay in early drug discovery
@nl
type
label
Inhibition of microglia activation as a phenotypic assay in early drug discovery
@ast
Inhibition of microglia activation as a phenotypic assay in early drug discovery
@en
Inhibition of microglia activation as a phenotypic assay in early drug discovery
@nl
prefLabel
Inhibition of microglia activation as a phenotypic assay in early drug discovery
@ast
Inhibition of microglia activation as a phenotypic assay in early drug discovery
@en
Inhibition of microglia activation as a phenotypic assay in early drug discovery
@nl
P2093
P2860
P921
P3181
P356
P1476
Inhibition of microglia activation as a phenotypic assay in early drug discovery
@en
P2093
B. S. Slusher
M. Figuera-Losada
P2860
P3181
P356
10.1177/1087057113499406
P407
P577
2014-01-01T00:00:00Z