The molecular mechanisms of OPA1-mediated optic atrophy in Drosophila model and prospects for antioxidant treatment
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Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's diseaseMitochondrial dynamism and heart disease: changing shape and shaping changeInner membrane fusion mediates spatial distribution of axonal mitochondriaMitochondria in the Aging Muscles of Flies and Mice: New Perspectives for Old CharactersMitochondrial fragmentation in neurodegenerationLoss of functional OPA1 unbalances redox state: implications in dominant optic atrophy pathogenesisHeterozygous mutation of Drosophila Opa1 causes the development of multiple organ abnormalities in an age-dependent and organ-specific mannerBacteria, yeast, worms, and flies: exploiting simple model organisms to investigate human mitochondrial diseasesThe Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in DrosophilaROS-mediated activation of Drosophila larval nociceptor neurons by UVC irradiation.Heterozygous mutation of Opa1 in Drosophila shortens lifespan mediated through increased reactive oxygen species production.Neurologic dysfunction and male infertility in Drosophila porin mutants: a new model for mitochondrial dysfunction and disease.Mitochondrial oxidative phosphorylation compensation may preserve vision in patients with OPA1-linked autosomal dominant optic atrophy.Mitochondrial optic neuropathies - disease mechanisms and therapeutic strategies.The optic nerve: a "mito-window" on mitochondrial neurodegenerationThe C8ORF38 homologue Sicily is a cytosolic chaperone for a mitochondrial complex I subunit.Two rare human mitofusin 2 mutations alter mitochondrial dynamics and induce retinal and cardiac pathology in Drosophila.Genome-wide screen for modifiers of Parkinson's disease genes in Drosophila.Dissociation of mitochondrial from sarcoplasmic reticular stress in Drosophila cardiomyopathy induced by molecularly distinct mitochondrial fusion defects.Impaired Mitochondrial Energy Production Causes Light-Induced Photoreceptor Degeneration Independent of Oxidative Stress.Modeling autosomal dominant optic atrophy using induced pluripotent stem cells and identifying potential therapeutic targetsThe role of PTEN-induced kinase 1 in mitochondrial dysfunction and dynamics.In search of proteins that are important for synaptic functions in Drosophila visual system.Mechanisms of mitochondrial fission and fusion.Dominant optic atrophy, OPA1, and mitochondrial quality control: understanding mitochondrial network dynamics.Disturbed mitochondrial dynamics and neurodegenerative disorders.The OPA1 Gene Mutations Are Frequent in Han Chinese Patients with Suspected Optic Neuropathy.Cross-Talk Between Mitochondrial Fusion and the Hippo Pathway in Controlling Cell Proliferation During Drosophila DevelopmentOpa1 deficiency in a mouse model of dominant optic atrophy leads to retinal ganglion cell dendropathy.Superoxide generation explains common features of optic neuropathies associated with cecocentral scotomas.Mitochondrial Changes in Cancer.Genotype–phenotype correlations in mitochondrial optic neuropathies
P2860
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P2860
The molecular mechanisms of OPA1-mediated optic atrophy in Drosophila model and prospects for antioxidant treatment
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The molecular mechanisms of OP ...... ects for antioxidant treatment
@ast
The molecular mechanisms of OP ...... ects for antioxidant treatment
@en
The molecular mechanisms of OP ...... ects for antioxidant treatment
@nl
type
label
The molecular mechanisms of OP ...... ects for antioxidant treatment
@ast
The molecular mechanisms of OP ...... ects for antioxidant treatment
@en
The molecular mechanisms of OP ...... ects for antioxidant treatment
@nl
prefLabel
The molecular mechanisms of OP ...... ects for antioxidant treatment
@ast
The molecular mechanisms of OP ...... ects for antioxidant treatment
@en
The molecular mechanisms of OP ...... ects for antioxidant treatment
@nl
P2093
P2860
P3181
P1433
P1476
The molecular mechanisms of OP ...... ects for antioxidant treatment
@en
P2093
Carrie B Brachmann
Douglas C Wallace
James Jiayuan Tong
Jessica Monserrate
Kimberly Nguyen
Phung Khanh Le
Stephanie Tse
Will Yarosh
P2860
P3181
P356
10.1371/JOURNAL.PGEN.0040006
P407
P50
P577
2008-01-01T00:00:00Z