Solution structure of recombinant hirudin and the Lys-47----Glu mutant: a nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing study
about
Crystal structure of the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitorThe refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationshipsSimulated annealing with restrained molecular dynamics using a flexible restraint potential: theory and evaluation with simulated NMR constraints.Proton bridging in the interactions of thrombin with hirudin and its mimics.Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential.New methods of structure refinement for macromolecular structure determination by NMR.Structural basis of RGD-hirudin binding to thrombin: Tyr3 and five C-terminal residues are crucial for inhibiting thrombin activity.Chemical synthesis and structural characterization of the RGD-protein decorsin: a potent inhibitor of platelet aggregation.Incorporation of noncoded amino acids into the N-terminal domain 1-47 of hirudin yields a highly potent and selective thrombin inhibitor.Crystal structure of the thrombin-hirudin complex: a novel mode of serine protease inhibitionElectrostatic interactions in the association of proteins: an analysis of the thrombin-hirudin complex.Representing an ensemble of NMR-derived protein structures by a single structure.Changes in interactions in complexes of hirudin derivatives and human alpha-thrombin due to different crystal forms.Analysis of sequence requirements for protein tyrosine sulfation.
P2860
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P2860
Solution structure of recombinant hirudin and the Lys-47----Glu mutant: a nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing study
description
1989 nî lūn-bûn
@nan
1989 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի մարտին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Solution structure of recombin ...... ical simulated annealing study
@ast
Solution structure of recombin ...... ical simulated annealing study
@en
Solution structure of recombin ...... ical simulated annealing study
@nl
type
label
Solution structure of recombin ...... ical simulated annealing study
@ast
Solution structure of recombin ...... ical simulated annealing study
@en
Solution structure of recombin ...... ical simulated annealing study
@nl
prefLabel
Solution structure of recombin ...... ical simulated annealing study
@ast
Solution structure of recombin ...... ical simulated annealing study
@en
Solution structure of recombin ...... ical simulated annealing study
@nl
P2093
P1433
P1476
Solution structure of recombin ...... ical simulated annealing study
@en
P2093
A M Gronenborn
P C Driscoll
P J Folkers
P304
P407
P577
1989-03-21T00:00:00Z