Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
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Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologiesInduction of tau pathology by intracerebral infusion of amyloid-beta -containing brain extract and by amyloid-beta deposition in APP x Tau transgenic miceMicroglial Priming and Alzheimer's Disease: A Possible Role for (Early) Immune Challenges and Epigenetics?Intracellular Calcium Dysregulation: Implications for Alzheimer's DiseaseFundamental role of pan-inflammation and oxidative-nitrosative pathways in neuropathogenesis of Alzheimer's disease in focal cerebral ischemic ratsFundamental role of pan-inflammation and oxidative-nitrosative pathways in neuropathogenesis of Alzheimer's diseaseImaging Multimodalities for Dissecting Alzheimer's Disease: Advanced Technologies of Positron Emission Tomography and Fluorescence ImagingThe Role of Oxidative Stress in Neurodegenerative DiseasesTau Oligomers: The Toxic Player at Synapses in Alzheimer's DiseaseAlzheimer's Disease: Mechanism and Approach to Cell TherapyThe "quad-partite" synapse: microglia-synapse interactions in the developing and mature CNSMouse models of frontotemporal dementiaTau-tubulin kinaseWho fans the flames of Alzheimer's disease brains? Misfolded tau on the crossroad of neurodegenerative and inflammatory pathwaysPathogenic protein seeding in Alzheimer disease and other neurodegenerative disordersPhysiological and pathological phosphorylation of tau by Cdk5Brain-penetrant microtubule-stabilizing compounds as potential therapeutic agents for tauopathiesNeuropathological alterations in Alzheimer diseaseTangles, Toxicity, and Tau Secretion in AD - New Approaches to a Vexing ProblemThe role of tau in neurodegenerative diseases and its potential as a therapeutic targetAltered brain energetics induces mitochondrial fission arrest in Alzheimer's Disease.Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain.Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy modelsDepletion of microglia and inhibition of exosome synthesis halt tau propagation.Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficitsAge-dependent neuroinflammation and cognitive decline in a novel Ala152Thr-Tau transgenic mouse model of PSP and AD.Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes3D Visualization of the Temporal and Spatial Spread of Tau Pathology Reveals Extensive Sites of Tau Accumulation Associated with Neuronal Loss and Recognition Memory Deficit in Aged Tau Transgenic MiceToxic tau oligomer formation blocked by capping of cysteine residues with 1,2-dihydroxybenzene groups.Tau physiology and pathomechanisms in frontotemporal lobar degenerationThe emerging role of peptidyl-prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's diseaseAnalyzing dendritic spine pathology in Alzheimer's disease: problems and opportunitiesThe Role of MAPT in Neurodegenerative Diseases: Genetics, Mechanisms and TherapyBezafibrate administration improves behavioral deficits and tau pathology in P301S miceDistinct α-synuclein strains differentially promote tau inclusions in neuronsExamining the relationship between head trauma and neurodegenerative disease: A review of epidemiology, pathology and neuroimaging techniquesRapamycin attenuates the progression of tau pathology in P301S tau transgenic miceA humanin derivative reduces amyloid beta accumulation and ameliorates memory deficit in triple transgenic miceTau-mediated synaptic damage in Alzheimer's diseaseZebrafish models of Tauopathy
P2860
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P2860
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
description
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im Februar 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/02/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/02/01)
@nl
наукова стаття, опублікована в лютому 2007
@uk
مقالة علمية (نشرت في فبراير 2007)
@ar
name
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
@ast
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
@en
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
@nl
type
label
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
@ast
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
@en
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
@nl
prefLabel
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
@ast
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
@en
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
@nl
P2093
P921
P3181
P1433
P1476
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
@en
P2093
John Q Trojanowski
Makoto Higuchi
Nobuhisa Iwata
Shu-Ming Huang
Takaomi C Saido
Tetsuya Suhara
Virginia M-Y Lee
P304
P3181
P356
10.1016/J.NEURON.2007.01.010
P407
P577
2007-02-01T00:00:00Z