Isolation, characterization and mutation analysis of PEX13-defective Chinese hamster ovary cell mutants
about
Molecular anatomy of the peroxin Pex12p: ring finger domain is essential for Pex12p function and interacts with the peroxisome-targeting signal type 1-receptor Pex5p and a ring peroxin, Pex10pTopogenesis of peroxisomal membrane protein requires a short, positively charged intervening-loop sequence and flanking hydrophobic segments. study using human membrane protein PMP34In vitro transport of membrane proteins to peroxisomes by shuttling receptor Pex19pThe membrane biogenesis peroxin Pex16p. Topogenesis and functional roles in peroxisomal membrane assemblyThe peroxisomal membrane protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p- and Pex16p-dependent pathwayHsp70 regulates the interaction between the peroxisome targeting signal type 1 (PTS1)-receptor Pex5p and PTS1PEX3 is the causal gene responsible for peroxisome membrane assembly-defective Zellweger syndrome of complementation group G.Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p WXXXF/Y motifs are critical for matrix protein import.The peroxin pex3p initiates membrane assembly in peroxisome biogenesisPex13 inactivation in the mouse disrupts peroxisome biogenesis and leads to a Zellweger syndrome phenotypePeroxisome biogenesis and peroxisome biogenesis disorders.A viable Arabidopsis pex13 missense allele confers severe peroxisomal defects and decreases PEX5 association with peroxisomes.Shuttling mechanism of peroxisome targeting signal type 1 receptor Pex5: ATP-independent import and ATP-dependent export.Peroxisome biogenesis and human peroxisome-deficiency disorders.Protein transport into peroxisomes: Knowns and unknowns.Distinct modes of ubiquitination of peroxisome-targeting signal type 1 (PTS1) receptor Pex5p regulate PTS1 protein import.Molecular mechanisms of import of peroxisome-targeting signal type 2 (PTS2) proteins by PTS2 receptor Pex7p and PTS1 receptor Pex5pL.Intracellular localization, function, and dysfunction of the peroxisome-targeting signal type 2 receptor, Pex7p, in mammalian cells.Disruption of the interaction of the longer isoform of Pex5p, Pex5pL, with Pex7p abolishes peroxisome targeting signal type 2 protein import in mammals. Study with a novel Pex5-impaired Chinese hamster ovary cell mutant.Pex5p stabilizes Pex14p: a study using a newly isolated pex5 CHO cell mutant, ZPEG101.CUL4A-DDB1-Rbx1 E3 ligase controls the quality of the PTS2 receptor Pex7p.
P2860
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P2860
Isolation, characterization and mutation analysis of PEX13-defective Chinese hamster ovary cell mutants
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Isolation, characterization an ...... ese hamster ovary cell mutants
@ast
Isolation, characterization an ...... ese hamster ovary cell mutants
@en
Isolation, characterization an ...... ese hamster ovary cell mutants
@nl
type
label
Isolation, characterization an ...... ese hamster ovary cell mutants
@ast
Isolation, characterization an ...... ese hamster ovary cell mutants
@en
Isolation, characterization an ...... ese hamster ovary cell mutants
@nl
prefLabel
Isolation, characterization an ...... ese hamster ovary cell mutants
@ast
Isolation, characterization an ...... ese hamster ovary cell mutants
@en
Isolation, characterization an ...... ese hamster ovary cell mutants
@nl
P2093
P356
P1476
Isolation, characterization an ...... ese hamster ovary cell mutants
@en
P2093
N Shimozawa
R J Wanders
P304
P356
10.1093/HMG/8.9.1673
P407
P577
1999-09-01T00:00:00Z