Hot spots in beta-catenin for interactions with LEF-1, conductin and APC - Wikidata - wikimedia - TriplyDB

Hot spots in beta-catenin for interactions with LEF-1, conductin and APC

Hot spots in beta-catenin for interactions with LEF-1, conductin and APC

http://www.wikidata.org/entity/Q28145062

about

Epithelial-mesenchymal transition and its implications for fibrosis beta-Catenin is a Nek2 substrate involved in centrosome separation.Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex.Wnt/beta-catenin signaling and small molecule inhibitors Crystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complex PX-RICS mediates ER-to-Golgi transport of the N-cadherin/beta-catenin complex The links between axin and carcinogenesis The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling The C. elegans SYS-1 Protein Is a Bona Fide β-Catenin Biochemical and Structural Characterization of β-Catenin Interactions with Nonphosphorylated and CK2-Phosphorylated Lef-1 Identification of a promoter-specific transcriptional activation domain at the C terminus of the Wnt effector protein T-cell factor 4 Identification of the LIM protein FHL2 as a coactivator of beta-catenin Testing models of the APC tumor suppressor/β-catenin interaction reshapes our view of the destruction complex in Wnt signaling Human APC sequesters β-catenin even in the absence of GSK-3β in a Drosophila model Actin-dependent membrane association of the APC tumour suppressor in polarized mammalian epithelial cells Wnt/beta-catenin signaling pathway is active in pancreatic development of rat embryo Long-term feeding of various fat diets modulates azoxymethane-induced colon carcinogenesis through Wnt/beta-catenin signaling in rats Acetylation of beta-catenin by p300 regulates beta-catenin-Tcf4 interaction Role for ICAT in beta-catenin-dependent nuclear signaling and cadherin functions.Beta-catenin binds to the activation function 2 region of the androgen receptor and modulates the effects of the N-terminal domain and TIF2 on ligand-dependent transcription An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway.Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing.Rigorous assessment and integration of the sequence and structure based features to predict hot spots.Small molecule-based disruption of the Axin/β-catenin protein complex regulates mesenchymal stem cell differentiation.Bcr is a negative regulator of the Wnt signalling pathway The divergent Caenorhabditis elegans beta-catenin proteins BAR-1, WRM-1 and HMP-2 make distinct protein interactions but retain functional redundancy in vivo Expression characteristics of β-catenin in scallop Chlamys farreri gonads and its role as a potential upstream gene of Dax1 through canonical Wnt signalling pathway regulating the spermatogenesis.Modeling the effect of APC truncation on destruction complex function in colorectal cancer cells Distinct functionality of dishevelled isoforms on Ca2+/calmodulin-dependent protein kinase 2 (CamKII) in Xenopus gastrulation Regulation of Wnt/beta-catenin signaling by protein kinases Cadherin sequences that inhibit beta-catenin signaling: a study in yeast and mammalian cells.Adenomatous polyposis coli (APC) regulates multiple signaling pathways by enhancing glycogen synthase kinase-3 (GSK-3) activity.Parallel duplication and partial subfunctionalization of β-catenin/armadillo during insect evolution.Destruction complex function in the Wnt signaling pathway of Drosophila requires multiple interactions between Adenomatous polyposis coli 2 and Armadillo Co-Occurring Atomic Contacts for the Characterization of Protein Binding Hot Spots Reversible modification of adenomatous polyposis coli (APC) with K63-linked polyubiquitin regulates the assembly and activity of the β-catenin destruction complex.Rescue of a Wnt mutation by an activated form of LEF-1: regulation of maintenance but not initiation of Brachyury expression In vitro and in vivo anti-tumor activity of CoQ0 against melanoma cells: inhibition of metastasis and induction of cell-cycle arrest and apoptosis through modulation of Wnt/β-catenin signaling pathways The Cdc42/Rac nucleotide exchange factor protein β1Pix (Pak-interacting exchange factor) modulates β-catenin transcriptional activity in colon cancer cells: evidence for direct interaction of β1PIX with β-catenin.Axin2 controls bone remodeling through the beta-catenin-BMP signaling pathway in adult mice.

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P2860

Hot spots in beta-catenin for interactions with LEF-1, conductin and APC

http://www.wikidata.org/entity/Q28145062

description

2000 nî lūn-bûn

@nan

2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2000年の論文

@ja

2000年論文

@yue

2000年論文

@zh-hant

2000年論文

@zh-hk

2000年論文

@zh-mo

2000年論文

@zh-tw

2000年论文

@wuu

name

Hot spots in beta-catenin for interactions with LEF-1, conductin and APC

@ast

Hot spots in beta-catenin for interactions with LEF-1, conductin and APC

@en

Hot spots in beta-catenin for interactions with LEF-1, conductin and APC

@nl

type

label

Hot spots in beta-catenin for interactions with LEF-1, conductin and APC

@ast

Hot spots in beta-catenin for interactions with LEF-1, conductin and APC

@en

Hot spots in beta-catenin for interactions with LEF-1, conductin and APC

@nl

prefLabel

Hot spots in beta-catenin for interactions with LEF-1, conductin and APC

@ast

Hot spots in beta-catenin for interactions with LEF-1, conductin and APC

@en

Hot spots in beta-catenin for interactions with LEF-1, conductin and APC

@nl

P1433

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P1433

Nature structural biology

P1476

Hot spots in beta-catenin for interactions with LEF-1, conductin and APC

@en

P2093

A Dell'Oro

http://www.w3.org/2001/XMLSchema#string

C Asbrand

http://www.w3.org/2001/XMLSchema#string

G Winbeck

http://www.w3.org/2001/XMLSchema#string

J Behrens

http://www.w3.org/2001/XMLSchema#string

J P von Kries

http://www.w3.org/2001/XMLSchema#string

N Sochnikova

http://www.w3.org/2001/XMLSchema#string

T Schwarz-Romond

http://www.w3.org/2001/XMLSchema#string

W Birchmeier

http://www.w3.org/2001/XMLSchema#string

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800-7

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scholarly article

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10.1038/79039

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P433

9

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7

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2000-09-01T00:00:00Z

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10966653

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