Group V phospholipase A2 induces leukotriene biosynthesis in human neutrophils through the activation of group IVA phospholipase A2 - Wikidata - wikimedia - TriplyDB

Group V phospholipase A2 induces leukotriene biosynthesis in human neutrophils through the activation of group IVA phospholipase A2

Group V phospholipase A2 induces leukotriene biosynthesis in human neutrophils through the activation of group IVA phospholipase A2

http://www.wikidata.org/entity/Q28215075

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Group V phospholipase A(2) increases pulmonary endothelial permeability through direct hydrolysis of the cell membrane Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic intervention Immobilized IL-8 Triggers Phagocytosis and Dynamic Changes in Membrane Microtopology in Human Neutrophils.Human group V phospholipase A2 induces group IVA phospholipase A2-independent cysteinyl leukotriene synthesis in human eosinophils Intracellular actions of group IIA secreted phospholipase A2 and group IVA cytosolic phospholipase A2 contribute to arachidonic acid release and prostaglandin production in rat gastric mucosal cells and transfected human embryonic kidney cells Localization of group V phospholipase A2 in caveolin-enriched granules in activated P388D1 macrophage-like cells.Arachidonic acid release from mammalian cells transfected with human groups IIA and X secreted phospholipase A(2) occurs predominantly during the secretory process and with the involvement of cytosolic phospholipase A(2)-alpha.A-002 (Varespladib), a phospholipase A2 inhibitor, reduces atherosclerosis in guinea pigs.Varespladib methyl in cardiovascular disease.Cellular arachidonate-releasing function of novel classes of secretory phospholipase A2s (groups III and XII).Eosinophil cysteinyl leukotriene synthesis mediated by exogenous secreted phospholipase A2 group X.Key role of group v secreted phospholipase A2 in Th2 cytokine and dendritic cell-driven airway hyperresponsiveness and remodeling.A novel anti-inflammatory role for secretory phospholipase A2 in immune complex-mediated arthritis.On the role of protein disulfide isomerase in the retrograde cell transport of secreted phospholipases A2 Group V secretory PLA2 regulates TLR2-dependent eicosanoid generation in mouse mast cells through amplification of ERK and cPLA2alpha activation.Importance of group X-secreted phospholipase A2 in allergen-induced airway inflammation and remodeling in a mouse asthma model.Multiple roles of phospholipase A2 during lung infection and inflammation.The involvement of phospholipases A2 in asthma and chronic obstructive pulmonary disease Secretory group V phospholipase A2 regulates acute lung injury and neutrophilic inflammation caused by LPS in mice.Protective Effects of Intratracheally-Administered Bee Venom Phospholipase A2 on Ovalbumin-Induced Allergic Asthma in Mice.Probing phospholipase a(2) with fluorescent phospholipid substrates.After FRANCIS: next steps in the clinical evaluation of varespladib methyl.Mechanism of regulation of group IVA phospholipase A2 activity by Ser727 phosphorylation.A novel role of group VIB calcium-independent phospholipase A2 (iPLA2gamma) in the inducible expression of group IIA secretory PLA2 in rat fibroblastic cells.Systematic evaluation of transcellular activities of secretory phospholipases A2. High activity of group V phospholipases A2 to induce eicosanoid biosynthesis in neighboring inflammatory cells.Lipid profiling of polarized human monocyte-derived macrophages.Secreted phospholipase A2 enzymes as therapeutic targets.Cytosolic phospholipase A2 is an effector of Jak/STAT signaling and is involved in platelet-derived growth factor BB-induced growth in vascular smooth muscle cells.Potentiation of tumor necrosis factor alpha-induced secreted phospholipase A2 (sPLA2)-IIA expression in mesangial cells by an autocrine loop involving sPLA2 and peroxisome proliferator-activated receptor alpha activation.Impact of a soluble phospholipase A2 inhibitor on inhaled allergen challenge in subjects with asthma.Diversity in secreted PLA2-IIA activity among inbred mouse strains that are resistant or susceptible to Apc Min/+ tumorigenesis.Group V secretory phospholipase A2 plays a pathogenic role in myocardial ischaemia-reperfusion injury.

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P2860

Group V phospholipase A2 induces leukotriene biosynthesis in human neutrophils through the activation of group IVA phospholipase A2

http://www.wikidata.org/entity/Q28215075

description

2002 nî lūn-bûn

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2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2002年の論文

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Group V phospholipase A2 induc ...... of group IVA phospholipase A2

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Group V phospholipase A2 induc ...... of group IVA phospholipase A2

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Group V phospholipase A2 induc ...... of group IVA phospholipase A2

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Group V phospholipase A2 induc ...... of group IVA phospholipase A2

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Group V phospholipase A2 induc ...... of group IVA phospholipase A2

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Group V phospholipase A2 induc ...... of group IVA phospholipase A2

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Alan R Leff

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Hiroyuki Sano

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Kwang Pyo Kim

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Nilda M Munoz

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Sang Kyou Han

http://www.w3.org/2001/XMLSchema#string

Wonhwa Cho

http://www.w3.org/2001/XMLSchema#string

Young Jun Kim

http://www.w3.org/2001/XMLSchema#string

P2860

A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis

cPLA2 is phosphorylated and activated by MAP kinase

Serine 727 phosphorylation and activation of cytosolic phospholipase A2 by MNK1-related protein kinases

Structure, function, and regulation of group V phospholipase A(2)

Groups IV, V, and X phospholipases A2s in human neutrophils: role in eicosanoid production and gram-negative bacterial phospholipid hydrolysis

Identification of phosphorylation sites of human 85-kDa cytosolic phospholipase A2 expressed in insect cells and present in human monocytes

5-Lipoxygenase products modulate the activity of the 85-kDa phospholipase A2 in human neutrophils

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP

Rapid import of cytosolic 5-lipoxygenase into the nucleus of neutrophils after in vivo recruitment and in vitro adherence

The functions of five distinct mammalian phospholipase A2S in regulating arachidonic acid release. Type IIa and type V secretory phospholipase A2S are functionally redundant and act in concert with cytosolic phospholipase A2

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scholarly article

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3387621

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10.1074/JBC.M205399200

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39

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277

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2002-07-17T00:00:00Z

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12124392

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