Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma - Wikidata - wikimedia - TriplyDB

Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma

Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma

http://www.wikidata.org/entity/Q28236409

about

The PRKCI and SOX2 oncogenes are coamplified and cooperate to activate Hedgehog signaling in lung squamous cell carcinoma Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2 Anti-Cancer Stem-like Cell Compounds in Clinical Development - An Overview and Critical Appraisal Radioresistance of Brain Tumors Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI Inhibitors Glioma Stem Cells and Their Microenvironments: Providers of Challenging Therapeutic Targets Glioma Stem Cells: Signaling, Microenvironment, and Therapy Targeting self-renewal pathways in cancer stem cells: clinical implications for cancer therapy Common stemness regulators of embryonic and cancer stem cells The Role of Hedgehog Signaling in Tumor Induced Bone Disease Hedgehog Signaling in the Maintenance of Cancer Stem Cells Cancer stem cells--important players in tumor therapy resistance G protein-coupled receptors as oncogenic signals in glioma: emerging therapeutic avenues Twisted tango: brain tumor neurovascular interactions Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapy Shh signal and its functional roles in normal and diseased brain Cancer stem cells in brain tumors and their lineage hierarchy Brain tumor stem cells: Molecular characteristics and their impact on therapy The potential origin of glioblastoma initiating cells Novel delivery strategies for glioblastoma Targeting glioma stem cells: a novel framework for brain tumors Glioma initiating cells form a differentiation niche via the induction of extracellular matrices and integrin αV Glioblastoma Stem-Like Cells: Characteristics, Microenvironment, and Therapy Molecular pathways: novel approaches for improved therapeutic targeting of Hedgehog signaling in cancer stem cells Hedgehog signaling and the Gli code in stem cells, cancer, and metastases Sustained proliferation in cancer: Mechanisms and novel therapeutic targets T cells enhance stem-like properties and conditional malignancy in gliomas Chemoresistance in prostate cancer cells is regulated by miRNAs and Hedgehog pathway Structural and logical analysis of a comprehensive hedgehog signaling pathway to identify alternative drug targets for glioma, colon and pancreatic cancer Hedgehog signaling pathway is active in GBM with GLI1 mRNA expression showing a single continuous distribution rather than discrete high/low clusters Self-renewal of acute lymphocytic leukemia cells is limited by the Hedgehog pathway inhibitors cyclopamine and IPI-926 Overcoming therapeutic resistance in glioblastoma: the way forward Notch inhibitors as a new tool in the war on cancer: a pathway to watch.The role of microRNAs in glioma initiation and progression.EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase CSNK1A1 and Gli2 as Novel Targets Identified Through an Integrative Analysis of Gene Expression Data, Protein-Protein Interaction and Pathways Networks in Glioblastoma Tumors: Can These Two Be Antagonistic Proteins?Recent patents for Hedgehog pathway inhibitors for the treatment of malignancy.Curcumin inhibits the side population (SP) phenotype of the rat C6 glioma cell line: towards targeting of cancer stem cells with phytochemicals.The sonic hedgehog signaling pathway is reactivated in human renal cell carcinoma and plays orchestral role in tumor growth.Activation of Sonic hedgehog signaling in neural progenitor cells promotes glioma development in the zebrafish optic pathway

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P2860

Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma

http://www.wikidata.org/entity/Q28236409

description

2007 nî lūn-bûn

@nan

2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Cyclopamine-mediated hedgehog ...... e cancer cells in glioblastoma

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Cyclopamine-mediated hedgehog ...... e cancer cells in glioblastoma

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Cyclopamine-mediated hedgehog ...... e cancer cells in glioblastoma

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type

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Cyclopamine-mediated hedgehog ...... e cancer cells in glioblastoma

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Cyclopamine-mediated hedgehog ...... e cancer cells in glioblastoma

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Cyclopamine-mediated hedgehog ...... e cancer cells in glioblastoma

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prefLabel

Cyclopamine-mediated hedgehog ...... e cancer cells in glioblastoma

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Cyclopamine-mediated hedgehog ...... e cancer cells in glioblastoma

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Cyclopamine-mediated hedgehog ...... e cancer cells in glioblastoma

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STEMCELLS.2007-0166

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Cyclopamine-mediated hedgehog ...... e cancer cells in glioblastoma

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Alex Lin

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Aneeka Chaudhry

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Angelo L Vescovi

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Eli E Bar

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Xing Fan

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P2860

Small molecule modulation of Smoothened activity

Cancerous stem cells can arise from pediatric brain tumors

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Stem cells, cancer, and cancer stem cells

Identification of human brain tumour initiating cells

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum

Patched and smoothened mRNA expression in human astrocytic tumors inversely correlates with histological malignancy

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

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785291

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10.1634/STEMCELLS.2007-0166

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10

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25

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Alessandro Olivi

Francesco DiMeco

Karisa C. Schreck

S G M Piccirillo

Charles G Eberhart

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2007-07-12T00:00:00Z

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