A fluorescent probe study of Ca2+ binding to the Ca2+-specific sites of cardiac troponin and troponin C
about
A novel mutant cardiac troponin C disrupts molecular motions critical for calcium binding affinity and cardiomyocyte contractilityMolecular and functional characterization of novel hypertrophic cardiomyopathy susceptibility mutations in TNNC1-encoded troponin CEffects of thin and thick filament proteins on calcium binding and exchange with cardiac troponin CAblation of myosin-binding protein-C accelerates force development in mouse myocardiumCa2+ - and cross-bridge-dependent changes in N- and C-terminal structure of troponin C in rat cardiac muscle.Structure and function of cardiac troponin C (TNNC1): Implications for heart failure, cardiomyopathies, and troponin modulating drugsEffect of calcium-sensitizing mutations on calcium binding and exchange with troponin C in increasingly complex biochemical systems.Mini-thin filaments regulated by troponin-tropomyosinDisparate fluorescence properties of 2-[4'-(iodoacetamido)anilino]-naphthalene-6-sulfonic acid attached to Cys-84 and Cys-35 of troponin C in cardiac muscle troponinCalmidazolium alters Ca2+ regulation of tension redevelopment rate in skinned skeletal musclePyrene-labeled cardiac troponin C. Effect of Ca2+ on monomer and excimer fluorescence in solution and in myofibrilsPredicting cardiomyopathic phenotypes by altering Ca2+ affinity of cardiac troponin C.Regulation of skeletal muscle tension redevelopment by troponin C constructs with different Ca2+ affinities.Cross-bridge versus thin filament contributions to the level and rate of force development in cardiac muscle.The time-course of Ca2+ exchange with calmodulin, troponin, parvalbumin, and myosin in response to transient increases in Ca2+Strong cross-bridges potentiate the Ca(2+) affinity changes produced by hypertrophic cardiomyopathy cardiac troponin C mutants in myofilaments: a fast kinetic approach.Mechanistic heterogeneity in contractile properties of α-tropomyosin (TPM1) mutants associated with inherited cardiomyopathies.Fluorescent Protein-Based Ca2+ Sensor Reveals Global, Divalent Cation-Dependent Conformational Changes in Cardiac Troponin CKinetic mechanism of the Ca2+-dependent switch-on and switch-off of cardiac troponin in myofibrils.The kinetic cycle of cardiac troponin C: calcium binding and dissociation at site II trigger slow conformational rearrangements.Using lanthanide ions to align troponin complexes in solution: order of lanthanide occupancy in cardiac troponin C.Functional consequences of the human cardiac troponin I hypertrophic cardiomyopathy mutation R145G in transgenic miceA functional and structural study of troponin C mutations related to hypertrophic cardiomyopathy.Troponin C in different insect muscle types: identification of two isoforms in Lethocerus, Drosophila and Anopheles that are specific to asynchronous flight muscle in the adult insect.Changes in the dynamics of the cardiac troponin C molecule explain the effects of Ca2+-sensitizing mutations.Molecular and functional consequences of mutations in the central helix of cardiac troponin C.A troponin switch that regulates muscle contraction by stretch instead of calcium.Challenging current paradigms related to cardiomyopathies. Are changes in the Ca2+ sensitivity of myofilaments containing cardiac troponin C mutations (G159D and L29Q) good predictors of the phenotypic outcomes?Papain labelled with fluorescent thiol-specific reagents as a probe for characterization of interactions between cysteine proteinases and their protein inhibitors by competitive titrations.Investigation of cation-binding properties of cardiac troponin C peptides by circular-dichroism spectroscopy.Free-energy linkage between folding and calcium binding in EF-hand proteins.Time-resolved tryptophan emission study of cardiac troponin I.Functional effects of a restrictive-cardiomyopathy-linked cardiac troponin I mutation (R145W) in transgenic mice.A quantitative analysis of cardiac myocyte relaxation: a simulation study.
P2860
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P2860
A fluorescent probe study of Ca2+ binding to the Ca2+-specific sites of cardiac troponin and troponin C
description
1980 nî lūn-bûn
@nan
1980 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1980 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1980年の論文
@ja
1980年論文
@yue
1980年論文
@zh-hant
1980年論文
@zh-hk
1980年論文
@zh-mo
1980年論文
@zh-tw
1980年论文
@wuu
name
A fluorescent probe study of C ...... ardiac troponin and troponin C
@ast
A fluorescent probe study of C ...... ardiac troponin and troponin C
@en
A fluorescent probe study of C ...... ardiac troponin and troponin C
@nl
type
label
A fluorescent probe study of C ...... ardiac troponin and troponin C
@ast
A fluorescent probe study of C ...... ardiac troponin and troponin C
@en
A fluorescent probe study of C ...... ardiac troponin and troponin C
@nl
prefLabel
A fluorescent probe study of C ...... ardiac troponin and troponin C
@ast
A fluorescent probe study of C ...... ardiac troponin and troponin C
@en
A fluorescent probe study of C ...... ardiac troponin and troponin C
@nl
P2093
P3181
P1476
A fluorescent probe study of C ...... ardiac troponin and troponin C
@en
P2093
J D Johnson
J D Potter
J H Collins
S P Robertson
P304
P3181
P407
P577
1980-10-25T00:00:00Z