Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor. Structure-activity relationship of 2-arachidonoylglycerol, ether-linked analogues, and related compounds
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2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces rapid actin polymerization in HL-60 cells differentiated into macrophage-like cellsHuman platelets respond differentially to lysophosphatidic acids having a highly unsaturated fatty acyl group and alkyl ether-linked lysophosphatidic acids2-arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptorThe endocannabinoid system as an emerging target of pharmacotherapyNoladin ether, a putative endocannabinoid, attenuates sensory neurotransmission in the rat isolated mesenteric arterial bed via a non-CB1/CB2 G(i/o) linked receptorDespite substantial degradation, 2-arachidonoylglycerol is a potent full efficacy agonist mediating CB(1) receptor-dependent G-protein activation in rat cerebellar membranesOmega-3 PUFAs Lower the Propensity for Arachidonic Acid Cascade OverreactionsWhy do cannabinoid receptors have more than one endogenous ligand?Marijuana, Spice 'herbal high', and early neural development: implications for rescheduling and legalization2-arachidonoylglycerol induces the migration of HL-60 cells differentiated into macrophage-like cells and human peripheral blood monocytes through the cannabinoid CB2 receptor-dependent mechanismNoladin ether, a putative novel endocannabinoid: inactivation mechanisms and a sensitive method for its quantification in rat tissuesThe endocannabinoid/endovanilloid N-arachidonoyl dopamine (NADA) and synthetic cannabinoid WIN55,212-2 abate the inflammatory activation of human endothelial cellsCannabinoid receptor 1 signaling in cardiovascular regulating nuclei in the brainstem: A reviewThe role of sex steroid hormones, cytokines and the endocannabinoid system in female fertilityEvidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cellsMonoacylglycerols activate TRPV1--a link between phospholipase C and TRPV1Pharmacological Inhibition of Monoacylglycerol O-Acyltransferase 2 Improves Hyperlipidemia, Obesity, and Diabetes by Change in Intestinal Fat UtilizationAddicting drugs utilize a synergistic molecular mechanism in common requiring adenosine and Gi-beta gamma dimersEndothelium-dependent metabolism by endocannabinoid hydrolases and cyclooxygenases limits vasorelaxation to anandamide and 2-arachidonoylglycerolThe inhibition of monoacylglycerol lipase by URB602 showed an anti-inflammatory and anti-nociceptive effect in a murine model of acute inflammationNeuropharmacology of the endocannabinoid signaling system-molecular mechanisms, biological actions and synaptic plasticity.Plasma 2-arachidonoylglycerol is a biomarker of age and menopause related insulin resistance and dyslipidemia in lean but not in obese men and womenHigh dietary arachidonic acid levels induce changes in complex lipids and immune-related eicosanoids and increase levels of oxidised metabolites in zebrafish (Danio rerio).Prolonged monoacylglycerol lipase blockade causes equivalent cannabinoid receptor type 1 receptor-mediated adaptations in fatty acid amide hydrolase wild-type and knockout miceAnandamide and diet: inclusion of dietary arachidonate and docosahexaenoate leads to increased brain levels of the corresponding N-acylethanolamines in piglets.Endocannabinoid binding to the cannabinoid receptors: what is known and what remains unknown.The endocannabinoid system: potential for reducing cardiometabolic riskType 1 cannabinoid receptor ligands display functional selectivity in a cell culture model of striatal medium spiny projection neurons.A novel activity of microsomal epoxide hydrolase: metabolism of the endocannabinoid 2-arachidonoylglycerol.The major central endocannabinoid directly acts at GABA(A) receptors.Heteromerization of GPR55 and cannabinoid CB2 receptors modulates signallingInhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2-arachidonoylglycerolIdentification of WIN55212-3 as a competitive neutral antagonist of the human cannabinoid CB2 receptorEnterocyte fatty acid-binding proteins (FABPs): different functions of liver and intestinal FABPs in the intestine.Task-specific enhancement of hippocampus-dependent learning in mice deficient in monoacylglycerol lipase, the major hydrolyzing enzyme of the endocannabinoid 2-arachidonoylglycerolLipopolysaccharide-induced murine embryonic resorption involves changes in endocannabinoid profiling and alters progesterone secretion and inflammatory response by a CB1-mediated fashion.Prevention of paclitaxel-induced neuropathy through activation of the central cannabinoid type 2 receptor system.Diet-induced changes in n-3- and n-6-derived endocannabinoids and reductions in headache pain and psychological distress.Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice.Endocannabinoid mechanisms of pain modulation
P2860
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P2860
Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor. Structure-activity relationship of 2-arachidonoylglycerol, ether-linked analogues, and related compounds
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Evidence that the cannabinoid ...... alogues, and related compounds
@ast
Evidence that the cannabinoid ...... alogues, and related compounds
@en
Evidence that the cannabinoid ...... alogues, and related compounds
@nl
type
label
Evidence that the cannabinoid ...... alogues, and related compounds
@ast
Evidence that the cannabinoid ...... alogues, and related compounds
@en
Evidence that the cannabinoid ...... alogues, and related compounds
@nl
prefLabel
Evidence that the cannabinoid ...... alogues, and related compounds
@ast
Evidence that the cannabinoid ...... alogues, and related compounds
@en
Evidence that the cannabinoid ...... alogues, and related compounds
@nl
P2093
P921
P356
P1476
Evidence that the cannabinoid ...... alogues, and related compounds
@en
P2093
H Takayama
T Miyashita
P304
P356
10.1074/JBC.274.5.2794
P407
P577
1999-01-01T00:00:00Z