The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking
about
The spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesisCellular Mechanisms of Ciliary Length ControlCilia/Ift protein and motor -related bone diseases and mouse modelsHow do cilia organize signalling cascades?Primary cilium and sonic hedgehog signaling during neural tube patterning: role of GPCRs and second messengersThe BBSome controls IFT assembly and turnaround in cilia.Intraflagellar transport complex structure and cargo interactions.CP110 and its network of partners coordinately regulate cilia assembly.IFT-Cargo Interactions and Protein Transport in CiliaMutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilizationCiliopathy-associated gene Cc2d2a promotes assembly of subdistal appendages on the mother centriole during cilia biogenesisGenome-wide ENU mutagenesis in combination with high density SNP analysis and exome sequencing provides rapid identification of novel mouse models of developmental diseaseAcentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryoFunctional interaction between autophagy and ciliogenesisCauli: a mouse strain with an Ift140 mutation that results in a skeletal ciliopathy modelling Jeune syndromeA mutation in the mouse ttc26 gene leads to impaired hedgehog signalingSubunit composition of the human cytoplasmic dynein-2 complexMutations in the gene encoding IFT dynein complex component WDR34 cause Jeune asphyxiating thoracic dystrophyMutations in DYNC2LI1 disrupt cilia function and cause short rib polydactyly syndromeShort-rib polydactyly and Jeune syndromes are caused by mutations in WDR60Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5.PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium functionA homozygous missense mutation in the ciliary gene TTC21B causes familial FSGSReview of literature: genes related to postaxial polydactyly.Specific variants in WDR35 cause a distinctive form of Ellis-van Creveld syndrome by disrupting the recruitment of the EvC complex and SMO into the cilium.Superresolution Pattern Recognition Reveals the Architectural Map of the Ciliary Transition ZoneCell cycle-dependent ubiquitylation and destruction of NDE1 by CDK5-FBW7 regulates ciliary lengthComponents of Intraflagellar Transport Complex A Function Independently of the Cilium to Regulate Canonical Wnt Signaling in Drosophila.Functional exploration of the IFT-A complex in intraflagellar transport and ciliogenesis.Intraflagellar transport is essential for mammalian spermiogenesis but is absent in mature sperm.Molecular mechanisms of midfacial developmental defects.T-box3 is a ciliary protein and regulates stability of the Gli3 transcription factor to control digit number.Mutations in human C2CD3 cause skeletal dysplasia and provide new insights into phenotypic and cellular consequences of altered C2CD3 functionIntraflagellar transport drives flagellar surface motility.Ciliary signaling cascades in photoreceptorsCilia-Associated Genes Play Differing Roles in Aminoglycoside-Induced Hair Cell Death in Zebrafish.Dysfunction of intraflagellar transport-A causes hyperphagia-induced obesity and metabolic syndrome.The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery.Destabilization of the IFT-B cilia core complex due to mutations in IFT81 causes a Spectrum of Short-Rib Polydactyly Syndrome.Role for the IFT-A Complex in Selective Transport to the Primary Cilium.
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P2860
The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking
description
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2012
@ast
im Juni 2012 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
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vedecký článok (publikovaný 2012/06/11)
@sk
vědecký článek publikovaný v roce 2012
@cs
wetenschappelijk artikel (gepubliceerd op 2012/06/11)
@nl
наукова стаття, опублікована в червні 2012
@uk
مقالة علمية (نشرت في 11-6-2012)
@ar
name
The IFT-A complex regulates Sh ...... d membrane protein trafficking
@ast
The IFT-A complex regulates Sh ...... d membrane protein trafficking
@en
The IFT-A complex regulates Sh ...... d membrane protein trafficking
@nl
type
label
The IFT-A complex regulates Sh ...... d membrane protein trafficking
@ast
The IFT-A complex regulates Sh ...... d membrane protein trafficking
@en
The IFT-A complex regulates Sh ...... d membrane protein trafficking
@nl
prefLabel
The IFT-A complex regulates Sh ...... d membrane protein trafficking
@ast
The IFT-A complex regulates Sh ...... d membrane protein trafficking
@en
The IFT-A complex regulates Sh ...... d membrane protein trafficking
@nl
P2093
P2860
P921
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P1476
The IFT-A complex regulates Sh ...... d membrane protein trafficking
@en
P2093
Alyson Ashe
David Beier
Karel F. Liem
Kathryn V. Anderson
Peter Satir
P2860
P304
P3181
P356
10.1083/JCB.201110049
P407
P577
2012-06-11T00:00:00Z